Uterine Disorders Flashcards
What is another name for leiomyoma
Uterine fibroids
What is a benign tumor of localized proliferation of smooth muscle cells surrounded by a pseudo capsule of compressed muscle fibers
Leiomyoma
Are Leiomyoma hormoally resonsive
Yes they come with a rapid growth if high estrogen and will often go away with menapause
Name the dx.
32 y/o Patient comes to you with bleeding from the vagina. Recently she has noticed her menses are getting heavier and longer and she has been trying to get pregnant over the past 2 years with no success.
On exam there is an irregular mobile hard mass. That has a cobblestone feel to it.
Leiomyoma
What is used to confirm the dx of Leiomyoma
Ultrasound
What is the treatment of Leiomyoma
NSAIDS and iron supplements if anemic
What can be used to minimize the bleeding of a Leiomyoma
Progesterone, GnRH agonist, and Danazol
What are the surgical options for Leiomyoma
Myomectomy: preserves pregnancy
Hysterectomy: No longer desire pregnancy
What is the definitive treatment of a Leiomyoma
Hysterectomy
What is the most common indication for a hysterectomy
Leiomyoma
What is known as an abnormal proliferation of endometrial tissue
Endometrial hyperplasia
Can endometrial hyperplasia go to cancer? And if so what kind?
Yes, Endometrial cancer
What hormone can cause endometrial hyperplasia
It is due to unopposed estrogen, there is no progesterone to balance out the estrogen
What is simple endometrial hyperplasia
Abnormal proliferation of both stromal and glandular tissue, basic structure not changed
What is complex endometrial hyperplasia
Abnormal proliferation of glandular tissue, abnormal structure with crowding of glands
What is atypical simple endometrial hyperplasia
Abnormal proliferation of both stromal and glandular tissue, basic structure not changed + atypia-large nuclei hyperchromatic
What is atypical complex endometrial hyperplasia
Abnormal proliferation of glandular tissue, abnormal structure with crowding of glands + atypia-large nuclei hyperchromatic
60 y/o women presents to you with abnormal bleeding. On exam the uterus feels enlarged and on US you find 6mm of thickness of endometrium. What is the next best step
Possibly cancer or endometrial hyperplasia need an endometrial biopsy to diagnose
What is the treatment of endometrial hyperplasia
Progestin for simple
Hysterectomy if atypia present due to high rate of possible cancer
When do you want to repeat an EMB after starting Progestin for endometrial hyperplasia
3 months