Pre-malignant And Malignant Of Cervix Flashcards
Where do the squamous and columnar epithelial meet
Squamocolumnar Junction (SJC)
Where is the most common site for abnormal cells to develop
Squamocolmnar junction
What type of cyst develop from a blockage of glandular cleft by squamous metaplasia
Nabothian cyst
What is the treatment for a nabothian cyst
No treatment needed
What is a pedunculated cyst that can be composed of any type of cervical cells and is benign
Cervical polyps
What is the treatment for a cervical polyp
Excised and sent for pathology
What are the two benign lesions of the cervix
Nabothian cyst
Cervical polyp
Name the term
Abnormal increase in size of each cell
Hypertorphy
Name the term
Abnormal increase in number of cells (but normal type and locations)
Hyperplasia
Name the term
Replacement of one mature cell type with another
Metaplastia
Name the term
Replacement of mature cells with immature cells
Dysplasia
Name the term
New growth, abnomral uncoordinated, excessive cell growth
Neoplasia
Name the term
Undifferentiated neoplasia, primitive, lack of specialization of any particular cell line
Anaplasia
What is a disordered growth and development of epithelial lining of cervix
Cervical intraepitheilial neoplasia
What is abnormal growth of lower 1/3 of epithelial lining
CIN 1
What is abnormal growth of lower 2/3
CIN2
What is abnormal growth of > 2/3
CIN 3
Abnormal growth full thickness
Carcinoma in situ
How do you evaluate cytology of squamous intraepitheial lesions
Pap smear
What classification is more associated with transient HPV infection
Low grade squamous intraepithelial lesion
What classificiation is more likely associated with persistent HPV infection
High grade squamous intraepithelial lesion
What is the primary causative factor for developing CIN and cervical cancer
HPV
Do condoms prevent all transmission of HPV
No due to scrotal labia transmission
What are the most common types of HPV to cause cancer
16 and 18
What are the two low risk HPV types to cause cancer, but more likely to cause genital warts
6 and 11
How do you treat HPV
Most spontaneously resolve on their own
How do you diagnose HPV
PAP smear
At what age would you think about screening for HPV
30-65
What two solutions can you use on colposcopy that can help find lesions
Acetic acid (vinager) Lugol's solution (iodine)
How do you treat an CIN 1
Monitor
How do you treat a CIN 2 or 3
Ablation or excision
What type of ablation is good for small lesions that are visable on the cervix
Cryotherapy and electrocautery
What type of ablation is used for large lesions
Laser
What type of treatment can be both diagnostic and therapeutic
Excision
What is the most common type of cervical cancer
Squamous cell cancer
What symptoms can one have who has cervical cancer
Abnormal bleeding is most common, pelvic pain and pressure, leukorrhea
How do you diagnose cervical cancer
Based on Pap smear
Where are you worried about mets going to with cervical cancer
Lungs get a CXR
What is the treatment for cervical cancer
CIS or IA1 total hysterectomy
When does one need to follow up with cervical cancer
Every 4 months for 2 years then
Every 6 months for 3 years then
Annually
What can be given for prevention of cervical cancer
HPV vaccine
What are the FDA approved vaccines for prevention of cervical cancer
Cerarix
Gardasil
Gardasil 9
What HPV types does Cervarix cover
16 and 18
What HPV types does Gardisil cover
6, 11, 16 and 18
What HPV types does Gardisil 9 cover
6, 11, 16, and 18 along with many more types
