Uterine Cancer Flashcards
what is most common cause of AUB-O ovulatroy dysfxn?
anovulatory cycles that lead to high estrogen from non ovulated follicle and eventual breakthrough bleeding
acute endometritis is from what?
usually bacteria
what cell is there in acute endometritis?
neutros
what are some causes of chronic endometritis?
PID, IUDs with actinomyces
what cell is there in chronic endometritis?
plasma cells
what is cause of endometrial hyperplasia?
unopposed estrogen
what is endometrial hyperplasia a precursor of?
endometrial carcinoma
what is clinical sign of endometrial hyperplasia?
abnormal uterine bleeding
what are the two types of endometrial hyperplasia? which is malignant?
hyperplasia without cytologic atypia/benign
cytologic atypical hyperplasia/premalignant
what is cytologic atypia in endometrial hyperplasia?
atypia of nucleus with enlargement and rounding, chromatin clumping, loss of nuclear polarity
how is endometrial hyperplasia without atypia treated>
with progesterone
what happens to gland:stroma ration in endometrial hyperplasia without atypia?
greater than1:1 but glands look normal
describe the process of moving from regular endometrium to endometrium carcinoma
start with anovulatory bleeding and see benign hyperplasia that changes to atypical hyperplasia and then endomterial carcinoma
name the four types of endometrial carcinoma?
serous
mucinous
endometroiod
clear cell
what is excluded in endometrial carcinoma?
stroma isnt present anymore