Urology Malignant Pathology Flashcards
what are the three classes of malignant urothelial carcinoma?
papillary urothelial non invasive
urothelial carciinoma in situ
invasive carcinoma of urthelial
what is the rare bladder tumor that is more common outside of US?
squamous cell carcinoma of the bladder
what is a frequent complication of renal pelvis and ureteral carcinoma?
kidney obstruction
what is the most common renal tumor?
renal cell carcinoma
what type of cancer is RCC?
adenocarcinoma
what are the four subtypes of RCC?
clear cell
papillary
clear cell papillary
chromophobe
what is most common subtype of RCC?
clear cell
how does the mass appear in RCC?
it is a solid mass in the kidney
what color are clear cell RCCs and why?
orangish yellow because of lipid in the tumor cells
how does a papillary RCC appear grossly?
multifocal lesions that are solid with papilary appearance
what does histo look like in clear cell RCC?
clear cells lol
what does histo look like in papillary RCC?
numerous papillary structures with central lighter staining
what syndrome is associated with clear cell papillary RCC?
von Hippel Lindau
what are oncocytomas made of?
closely packed epithelial cells
what is the color characteristic of an oncocytoma?
eosinophilic because of abundance of mitochondria
where do oncocytomas arise from?
the intercalated cells of the CD
where do angiomyolipoma often arise from?
renal capsule
what is angiomyolipoma associated with often?
tuberous sclerosis
what is the pediatric renal tumor?
Wilms tumor
what type of tumor is WIlms tumor?
nephroblastoma
what is Wilms tumor made up of/
primitive glomerular structures and tubules
what are the three tumor markers for testicular cancer?
AFP
bHCG
LDH
what are the four non seminoma germ cell tumors?
yolk sac
choriocarcinoma
teratoma
embryonal carcinoma
what tumor marker is usually positive in seminoma?
LDH
