Usual Interstitial Pneumonitis Flashcards
1
Q
What is usual interstitial pneumonitis?
A
- Patchy interstitial chronic inflammation
2
Q
What are the causes of interstitial pneumonitis?
A
- Type 2 pneumocyte hypoplasia
- Smooth muscle
- Vascular proliferation
- Injury
3
Q
Symptoms?
A
- Dyspnoea
- Cough
4
Q
Signs?
A
- Basal crackles
- Cyanosis
- Clubbing
5
Q
Initial investigations?
A
- CxR
- Peak flow
- Gas transfer
6
Q
What can be seen on a CxR of interstitial pneumonitis?
A
- Basal/posterior fibrosis
- Honeycombing fibrosis (look up)
- Diffuse infiltrates
- Cysts
7
Q
What would be the results of the peak flow?
A
- Reduced significantly
8
Q
What would be the result of a CO gas transfer?
A
- High levels of CO would be detected on expiration
9
Q
What are the treatments?
A
- Very few
- Some response to steroids
- Antifibrotics
10
Q
What are two common antifibrotics?
A
- Pirfenidone
- Nintedanib
