Asthma Flashcards

1
Q

What is the clinical syndrome of asthma defined by?

A
  • Increased responsiveness of the trachea and bronchi to various stimuli
  • Resulting in reversible narrowing of airways that is relieved either spontaneously or with treatment
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2
Q

What is always present with asthma?

A
  • Wheeze
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3
Q

What type of sensitivity results in asthma?

A
  • Type 1 hypersensitivity
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4
Q

What can wheeze commonly be confused with?

A
  • Rattle
  • Stertor
  • Stridor
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5
Q

What can asthma commonly be misdiagnosed for?

A
  • Bronchitis
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6
Q

What ways can asthma be reversed?

A
  • Bronchodilators

- Corticosteroids

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7
Q

How can asthma vary daily?

A
  • Worse at night and in the morning
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8
Q

How can asthma vary weekly?

A
  • At work in week

- Better at weekends

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9
Q

How can asthma vary annually?

A
  • Environmental allergens
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10
Q

What are the goals of treatment following a finalised asthma diagnosis?

A
  • Minimalise symptoms
  • Minimalise medicaton
  • No exacerbations
  • No limitations on physical activity
  • Normal lung function
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11
Q

What are the clinical symptoms of asthma?

A
  • Wheeze
  • Dyspnoea
  • Chest tightness
  • Cough (dry - usually only in paediatric asthma)
  • Sputum (occasionally)
  • VARIABILITY
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12
Q

What are the clinical signs of asthma?

A
  • Breathlessnes on exertion
  • Hyperexpanded chest
  • Wheezes
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13
Q

What other clinical symptoms and signs would mean it wasn’t asthma?

A
  • Clubbing
  • Cervical lymphadenopathy
  • Stridor
  • Asymmetrical expansion
  • Dull percussion notes
  • Crepitations (crackles)
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14
Q

What conditions would be more likely on a dull percussion note?

A
  • Lobar collapse

- Pleural effusion

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15
Q

What conditions would be more likely with crepitations?

A
  • Bronchitis
  • CF
  • Alveolitis
  • LVF
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16
Q

What are the risk factors for asthma?

A
  • Genetic
  • Occupation
  • Smoking
  • Obesity
  • Diet
  • Microbe exposure
  • Chemical products
  • Environmental exposure
  • Inherently abnormal lungs
17
Q

What genetic factors can increase asthma risk?

A
  • Atopy (inherited tendency for IgE response to allergens
18
Q

What occupational risk factors are there

A
  • Simply means what people work with

- People working with animals, grains, enzymes etc may be more susceptible

19
Q

How can smoking increase risk of asthma?

A
  • Grandmother effect

- Mother smoking during pregnancy

20
Q

How can obesity increase risk of asthma?

A
  • BMI linked to asthma

- Obesity increases inflammatory response

21
Q

How can diet increase asthma risk?

A
  • Lack of certain vitamins
  • Anti-O’s
  • Fruit
22
Q

How can exposure to microbes affect asthma risk?

A
  • Young exposure to certain microbes reduces risk

- Farm children far less likely to develop asthma

23
Q

What environmental antigens are there that can influence risk?

A
  • Dust mites (actually reduce risk)
  • Cats
  • Grass pollen
24
Q

What things can exacerbate asthma?

A
  • Exercise
  • Cold air
  • Smoke
  • Perfume
  • URTI’s
  • Pets
  • Grass pollen