Hypersensitivity Pneumonitis Flashcards

1
Q

What is hypersensitivity pneumonitis?

A
  • Inflammation of the alveoli caused by hypersensitivity to inhaled dusts
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2
Q

What presents with hypersensitivity pneumonitis?

A
  • Granulomas
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3
Q

What type of hypersensitivity reactions result in the formation of granulomas?

A

Immune complex mediated combined type 3 and 4

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4
Q

What happens to gas transfer in hypersensitivity pneumonitis?

A
  • Reduced
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5
Q

What can result from the reduced gas transfer?

A
  • Respiratory failure
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6
Q

What will type 4 reaction result in?

A
  • Soft centriacinar epithelioid granuloma
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7
Q

What zone is affected by hypersensitivity pneumonitis?

A
  • Upper zone
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8
Q

What are the symptoms?

A
  • Fever
  • Dry cough
  • Chills following exposure to antigen
  • Wheeze
  • Malaise
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9
Q

What are the signs?

A
  • Dyspnoea
  • Tachypnoea
  • Crackles
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