Urticaria Flashcards
Urticaria
Hives
Wheal and flare type reaction
Is urticaria pruritic?
Yes pruritic
Itching in urticaria is caused by
Histamine and other mediators released from mast cells
Pathogenesis
Mast cell degranulation
IgE
Allergen or drugs
Pressure friction temperature
The main clinical feature of urticaria
Wheal or hives
Clinical features of hives or wheals
Central swelling
Surrounded by erythema
Pruritus
Transitory nature 1-24 hrs
Acute vs chronic urticaria
Acute - less than 6 weeks
Chronic - more than 6 weeks
Acute urticaria
Unknown cause
Maybe drugs nsaid
Infection
Food components
Acute urticaria diagnosis
No testing
Acute urticaria therapy
Antihistamines
Corticosteroids
Chronic urticaria
Auto reactivity of mast cells
Autoimmune urticaria
Chronic infections
Chronic urticaria diagnosis
History of patient
Laboratory diagnosis
Autoantibodies
Increased esr
Therapy
Antihistamines
Ketotifen
Doxepin
Corticosteroids but not for long time
