Lichen Planus Flashcards

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1
Q

Lichen planus

A

Violaceous flat topped papules
Oral erosions

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2
Q

Is lichen planus pruritic?

A

Yes

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3
Q

Pathogenesis

A

Th cells
Cytotoxic cells
INF gamma
TNF
HLA
Adhesion on keratinocytes
Basal cell layer damage
Reactive hyperkeratosis

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4
Q

Clinical features

A

Glistening violaceous flat topped papules
Wickham striae (fine Lacy white markings on top of papules)
Kobner phenomenon
Pruritic

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5
Q

Kobner phenomenon in lichen planus

A

Positive

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6
Q

Predilection sites

A

Wrist
Ankles
Anterior shin
Buttocks

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7
Q

Lichen planus variants

A

Hypertrophic lichen planus
Lichen planopilaris
Linear lichen planus
Erosive lichen planus
Bullous lichen planus
Lichen planus pemphigoid
Atrophic lichen planus

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8
Q

Spider web appearance on mucosa in lichen planus

A

Buccal mucosa
Tongue
Hard palette
Lips
Genial mucosa

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9
Q

Erosive lichen planus diff diagnosis

A

SLE

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10
Q

Treatment

A

Corticosteroids topical
Systemic corticosteroids
Acitretin
Anti malarial
Cream PUVA

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