Lichen Planus Flashcards
Lichen planus
Violaceous flat topped papules
Oral erosions
Is lichen planus pruritic?
Yes
Pathogenesis
Th cells
Cytotoxic cells
INF gamma
TNF
HLA
Adhesion on keratinocytes
Basal cell layer damage
Reactive hyperkeratosis
Clinical features
Glistening violaceous flat topped papules
Wickham striae (fine Lacy white markings on top of papules)
Kobner phenomenon
Pruritic
Kobner phenomenon in lichen planus
Positive
Predilection sites
Wrist
Ankles
Anterior shin
Buttocks
Lichen planus variants
Hypertrophic lichen planus
Lichen planopilaris
Linear lichen planus
Erosive lichen planus
Bullous lichen planus
Lichen planus pemphigoid
Atrophic lichen planus
Spider web appearance on mucosa in lichen planus
Buccal mucosa
Tongue
Hard palette
Lips
Genial mucosa
Erosive lichen planus diff diagnosis
SLE
Treatment
Corticosteroids topical
Systemic corticosteroids
Acitretin
Anti malarial
Cream PUVA