Atopic Dermatitis Flashcards

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1
Q

Atopic dermatitis

A

Dermatitis in people with atopy

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2
Q

Atopy

A

Familial predisposition to development of
Allergic asthma
Conjunctivitis
Rhinitis
Atopic dermatitis

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3
Q

Pathogenesis
Extrinsic atopic dermatitis

A

IgE elevated
Type 1 hypersensitivity
CD4 cells

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4
Q

Intrinsic atopic dermatitis

A

No immunological changes as in EADS
CD8 cells in infiltrate

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5
Q

Clinical features
Major

A

Pruritis
Typical dermatitis
Positive family history for atopy
Chronic

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6
Q

Minor features

A

Cradle cap
Yellow crust on scalp
Dry skin

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7
Q

Predilection sites

A

Face
Flexures
Hands and feet
Nape of neck

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8
Q

Diagnosis

A

Clinical features
IgE elevated
Eye examination
Prick test
Patch test

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9
Q

Therapy

A

Tacrolimus
Corticosteroids
Antihistamines

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