urinary system (wk 7) Flashcards
what does the suffix Ren- mean?
kidneys, eg Renal = related to the kidneys
what does the suffix Nephr- mean?
kidneys, eg Nephritis = inflammation of the kidneys
what does the suffix -itis mean?
-itis = inflammation
what does the prefix Pyelo- mean?
renal pelvis of the kidney, eg Pyelonephritis = inflammation of the renal pelvis and kidneys
what does the prefix Glomerulo- mean?
Glomeruli, eg Glomerulonephritis = inflammation of the glomeruli in the kidneys
what does the prefix Cyst- mean?
bladder, eg Cystitis = inflammation of the bladder
what does the suffix -uria mean?
a condition of the urine, eg Anuria = absence of urine production or very low urine production (a = without)
what is a compound of a cation and an anion, so electrically neutral?
salt
the steep gradient of which electrolyte between the fluid inside and outside the cell makes it critical for all electrophysiological processes, that is, action potentials
primary functions of sodium (Na+)
similar to sodium, the steep concentration gradient between the fluid inside and outside the cell makes which electrolyte critical to the functioning of neurons and muscle cells?
primary functions of potassium (K+)
which electrolyte is one of the main components of bone, it is also required for muscle contraction, plateau phase of the cardiac action potential, intracellular signalling, blood clotting, and the excitation of neurons?
primary functions of calcium (Ca2+)
the high concentration of which electrolyte in the fluid outside the cells makes it an important osmotic particle, also a critical component of some physiological processes such as the production of hydrochloric acid in the stomach?
primary functions of chloride (Cl-)
which electrolyte is critical to multiple cellular processes, as it activates many enzymes, also an important component of bone tissue?
primary functions of magnesium (Mg2+)
The ion composition of plasma and IF is roughly the same - true or false?
true - ions can move between the intravascular and interstitial fluid compartments, so the ion composition of each compartment is roughly the same
The protein concentration of plasma and IF is roughly the same - true or false?
false - proteins cannot usually escape from capillaries, so proteins are largely absent from interstitial fluid
what is IF?
interstitial fluid - fluid found in the spaces around cells (leaked out of capillaries). helps bring oxygen and nutrients to cells and to remove waste products from them.
Which fluid compartment contains the highest concentration of sodium - ECF or ICF?
ECF - higher concentrations of sodium inside the cell and higher concentrations of potassium outside the cell is the basis of cell-cell communication
what is ICF?
intracellular fluid
what is ECF?
extracellular fluid
Water will move from a solution with lower osmolarity to a solution with higher osmolarity - true or false?
true - water moves to areas of higher osmolarity in order to reach equilibrium between the two solutions
what are nephrons?
the microscopic functional unit of the kidney, found in both the cortex and medulla - urine formed by the nephrons flows into the renal pelvis, then to the ureter
what is haematopoiesis, and is it a function of the kidneys?
production of blood cells - no
do the kidneys regulate red blood cell production in the bone marrow?
yes - by releasing a hormone called erythropoietin
which of: peristaltic contractions of ureteral smooth muscle, pressure in the renal pelvis and osmotic gradients do Not contribute to the flow of urine from the renal pelvis to the bladder?
osmotic gradients
What will happen to the GFR (glomerular filtration rate) if the diameter of the efferent arteriole decreases?
it will increase - constriction of the efferent arteriole “clogs the drain”. blood backs up within the glomerulus, which increases hydrostatic pressure and the GFR
what does ADH (antidiuretic hormone) do?
decreases water loss through the kidney
what does aldosterone do?
increases renal sodium reabsorption, which causes water retention and increased blood volume
does vasoconstriction increase peripheral resistance or blood volume?
peripheral resistance
what does ANP (atrial natriuretic peptide) do?
increases sodium and water loss through kidneys
what does the renin-angiotensin-aldosterone system (RAAS) do?
increases sympathetic nervous system activity, increases sodium and water retention by the kidneys, causes vasoconstriction of arterioles
what is a mineralocorticoid produced in the adrenal gland, that causes an increase in the number of Na+/K+ pumps and Na+ transporters in the kidney tubules to increase permeability and reabsorption of Na+ from the filtrate? also results in secretion of K+ into the filtrate (Na+/K+ pump transports K+ in the opposite direction of Na+)
aldosterone
what is produced in the hypothalamus and stored in the posterior pituitary gland, promotes reabsorption of water into the blood and subsequently reduces urine output (by inserting aquaporins into the cells of the distal tubules and collecting ducts so water can be rapidly reabsorbed)?
ADH (antidiuretic hormone)
what is the most important mechanism used by the urinary system to correct a high acid load?
generation of new bicarbonate (buffer) molecules
If a urine sample contains a high concentration of bicarbonate, which acid–base disorder would be suspected - acidosis or alkalosis?
alkalosis - if bicarbonate is being excreted in the urine, it means there is no excess H+ to be buffered
how do buffers correct metabolic alkalosis?
H+ ions are released
how does the respiratory system correct metabolic acidosis?
respiration slows to contain more CO2, which reacts to form H+ and HCO3-
how does the renal system correct metabolic acidosis?
bicarbonate is excreted in the urine so that H+ in the blood remains unbuffered
what is polyuria?
peeing more than usual
what is polydipsia?
drinking more than normal
what is urinary incontinence?
leaking urine
what is spraying in cats?
usually involves small volumes of urine sprayed onto vertical surfaces, with normal litter tray use
what is inappropriate urination in cats?
usually involves normal volumes of urine voided onto horizontal surfaces, without normal use of a litter tray at the same time
what clinical signs might an owner notice if the animal has problems with the urinary system?
- drinking more than normal
- leaking urine
- straining
- peeing more than usual
*note - these signs are not exclusive to the urinary system
what animal is this? use communal dung piles for urination and defecation (with defecation usually occurring first), turn around and squat, have a caudally facing prepuce and urinate backwards?
camelids
What information can you gather by palpating the urinary bladder?
- indication of size
- content (eg is it gritty?)
- if it is painful
how would you palpate a kidney on a dog - abdominal palpation or rectal palpation?
abdominal palpation - small animals can have bladder and kidneys palpated this way, whereas in large animals the body wall is too thick
how would you palpate the left kidney on a horse - abdominal palpation, or rectal palpation?
rectal palpation, and the right kidney is too far cranial to palpate at all
different species have different shaped kidneys. A vet performs abdominal palpation on a dog and reports that the kidneys feel lumpy. Is this likely to be normal?
no - dog kidneys are normally smooth
where is the penis located on cats?
(roughly under tail) caudally, ventral to the testicles and anus
what is unique about the penis of camelids?
The penis of camelids has a fibrocartilaginous process craniodorsal to the urethral opening, which means sedation/anaesthesia or an erection is necessary for examination
What anatomical difference between the urethra of the male and female cat predisposes male cats to obstruction of their urethra?
the male urethra is narrower and longer than the female
is marking behaviour or inappropriate urination an act of communication?
marking behaviour
true or false - both inappropriate urination and marking may be influenced by medical issues and stress?
true
How would you palpate the left kidney on a cow, and what would it feel like?
the left kidney on a cow can be palpated rectally. cattle have a lobulated kidney, so the surface feels lumpy (not smooth)
Which species is a os penis normally found in?
dog
which organs regulate fluid balance in the body?
gastrointestinal tract, kidneys
what is interstitial fluid?
the fluid between cells
what is intravascular fluid?
the fluid within blood vessels (that is, plasma)
what is intracellular fluid out of: fluid outside cells, fluid surrounding the brain, interstitial fluid, fluid inside blood vessels, fluid in between cells, fluid in joint cavities, fluid inside cells, and intravascular fluid?
intracellular fluid is just that - the fluid inside cells. everything else is extracellular.
the body loses water via two routes - what is sensible vs insensible water loss?
sensible water loss - measurable and noticeable, eg urination
insensible water loss - less noticeable and unmeasurable, eg water in faeces or evaporation from lungs or skin