Urinary System 1

Question 1

Which part of the kidney receives a greater blood volume, medulla or cortex?

Answer 1

Cortex

Question 2

What are the layers of the filtering membrane of the glomerulus?

Answer 2

Fenestrated endothelial cells Glomerular basement membrane (double membrane) Podocytes (visceral epithelial cells)

Question 3

Where does the nephrin reside?

Answer 3

Slit pore diaphragm

Question 4

The glomerular filtration apparatus is a selective filter that prohibits the passage of which types of molecules?

Answer 4

Large Negatively charged

Question 5

Where do juxtaglomerular cells reside?

Answer 5

Afferent arteriole

Question 6

What structure resides within the distal tubule?

Answer 6

Macula densa

Question 7

Which cells produce renin?

Answer 7

Juxtaglomerular cells

Question 8

An increase in SNGFR (single nephron glomerular filtration rate) can lead to what type of injury to those remaining glomeruli?

Answer 8

Hyperfiltration injury, which can lead to sclerosis and end-stage renal disease

Question 9

Is the blood pressure through the glomerulus high or low?

Answer 9

High

Question 10

List 5 functions of the kidney

Answer 10

1. Maintain acid/base balance 2. Regulate water volume 3. Maintain ion balance 4. Rid metabolic wastes (urea, creatinine) 5. Endocrine functions

Question 11

How might a decrease in renal mass can lead to anemia?

Answer 11

Decreased erythropoietin production