Bones review 2 Flashcards

1
Q

List 3 forms of chondrodysplasia/skeletal dysplasias:

A
  1. Dwarfism
  2. Angular deformities
  3. Amelia (complete limb loss)
  4. Hemimelia (missing part of a limb)
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2
Q
  1. What condition is chondrodysplasia most similar to and why?
  2. How do these two conditions differ?
A
  1. Rickets - Chondrodysplasia is a condition associated with the thickening of the growth plate as well.
  2. Chondrodysplasia is not associated with any nutritional deficiencies, such as Ca, P or vitamin D.
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3
Q

What is the term for a mandible that expands past where it should?

A

Prognathism

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4
Q

What is the term for too short of a mandible?

A

Brachygnathism

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5
Q

What teratogen causes cyclopeia in sheep on the 14th day of gestation?

A

Veratrum californicum

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6
Q

Define osteochondrosis.

A

Focal defect in endochondral ossification.

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7
Q

Which areas of the bone are affected by osteochondrosis?

A
  1. Articular-epiphyseal complexes
  2. Physes (growth plates)
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8
Q

What is the condition called when a flap of articular cartilage breaks lose?

A

Osteochondrosis dissecans

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9
Q

Osteochondrosis develops because of an insufficient blood supply and necrosis of what?

A

Chondrocytes

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10
Q

Chondrodysplasias are all abnormalities of what?

A

Chondrodysplasias are abnormalities of cartilage, which leads to abnormal endochondral ossification and secondary bone deformities.

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11
Q

Osteochondrosis is typically a disease that mostly affects which types of animals?

A

Those grown for rapid, long bone growth

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12
Q

What is the mechanism of osteochondrosis dessicans?

A
  1. Premature vessel closure
  2. Ischemia at the AE complex
  3. Cartilage necrosis
  4. Focal EO failure
  5. Adjacent EO progression
  6. Deformation of articular surface
  7. Cartilage breaks free
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13
Q

What mechanism causes a net decrease in bone mass?

A

Osteoclastic activity exceeds bone production

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14
Q

What might cause osteoporosis?

A
  1. Disuse
  2. Nutritional deficiencies
  3. Hyperparathyroidism
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15
Q

What is a focal loss of bone?

A

Bone lysis

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16
Q

What is diffuse loss of bone?

A

Osteoporosis / osteopenia

17
Q

Define hyperostosis.

A

Increased production of bone.

18
Q

What conditions could cause hyperostosis to develop?

A
  1. Trauma (periosteal injury)
  2. Compression
  3. Neoplasm
  4. Chronic inflammation
19
Q

What is osteosclerosis?

A

A failure of osteoclasis (decrease in the number and activity of osteoclasts)

20
Q

What is osteopetrosis?

A

Diffuse osteosclerosis of trabecular (spongy) bone

21
Q
  1. What is this bone conditioned called?
  2. The failure of what caused this?
A
  1. Osteopetrosis
  2. Osteoclasitic activity failed
22
Q

What is the #1 cause of osteonecrosis?

A

Ischemia

23
Q

Fracture through a growth plate will result in what?

A

Premature closure

24
Q
A