Urinary Lab Flashcards
What are the functions of the urinary system?
Excretion of liquid waste and exogenous substances
Filter blood
What does the urinary system regulate?
Blood pH
Blood pressure
Blood volume
What does the urinary system produce?
Renin and erythropoietin
What are the principal organs in the urinary system?
Kidneys (2), ureters (2), urinary bladder, urethra
Why is the left kidney higher than the right kidney?
Because the liver is on the right side (RUQ)
What is the normal parameters for appearance of urine?
shade of yellow to deep amber
What is the normal parameters for turbidity of urine?
cloudy/clear
What is the normal parameter for odor of urine?
“aromatic”
What is the normal parameter of pH of urine?
6 (range of 4.5-8.2)
What is the normal parameter for specific gravity of urine?
1.001-1.028
What is the normal parameter of production rate of urine?
1-1.3mL/min (about 1L/24 hours)
What is specific gravity?
the density of urine divided by the density of distilled water (measure of how concentrated the urine is)
What is production rate?
the amount of urine being produced per minute
What is the equation for production rate?
volume (mL) / time since last voided
Water, ions, urea, uric acid, ammonia, creatinine are all what type of components of urine?
normal components
Glucose, large proteins, RBCs, WBCs, bacteria, ketone bodies, and casts are what type of components of urine?
abnormal components
What is glucosuria?
the presence of glucose in urine
Albuminuria
the presence of albumin (protein) in the urine
Hematuria
the presence of RBCs in the urine
Pyuria
the presence of WBCs in the urine
Ketonuria
the presence of ketone bodies in the urine
What are the protective layers of the kidney?
Renal Fascia,
Adipose Capsule,
Renal Capsule
What are the regions of the kidney?
Renal Cortex,
Renal Medulla,
Renal Sinus
What parts of the kidney make up the renal medulla?
Renal pyramids
Renal papilla
What parts of the kidney make up the renal sinus?
Minor and major calyces
Renal pelvis
Vessels
Adipose tissue
The papilla of a renal pyramid is at the edge of ________
a minor calyx
2-3 minor calyces make up ________
1 major calyx
2-3 major calyces make up _____
the renal pelvis
What is a nephron?
the functional unit of the kidney
What are the functions of a nephron?
filtration, reabsorption, secretion
Filtration
blood filtered into glomerulus into renal corpuscle
Reabsorption
substances move from nephron tubule back into blood stream
What are the two regions of the nephron?
Renal corpuscle and renal tubule
What makes up the renal corpsucle?
Glomerulus and Bowman’s capsule
What makes up the renal tubule?
Proximal convoluted tubule
Descending limb of nephron loop
Ascending limb of nephron loop
Distal convoluted tubule
Collecting duct
Papillary duct
where the nephron connects to the renal papilla and renal pyramid
What are the two types of nephrons?
Cortical nephrons and Juxtamedullary nephrons
What type of nephron contains peritubular capillaries?
Cortical nephrons
What type of nephron contains peritubular capillaries and vasa recta along the loop of henle?
Juxtamedullary nephrons
Renal blood flow
- Renal artery
- Segmental artery
- Interlobar artery
- Arcuate artery
- Cortical radiate artery
- Afferent arteriole
- Glomerulus/Glomerular capillaries
- Efferent arterioles
- Peritubular capillaries/vasa recta
- Cortical radiate vein
- Arcuate vein
- Interlobar vein
- Renal vein
Filtrate/Urine flow
- Glomerulus
- Proximal convoluted tubule
- Descending limb of loop of Henle
- Thin ascending limb of loop of Henle
- Thick ascending limb of Loop of Henle
- Distal convoluted tubule
- Collecting duct
- Renal pyramid
- Renal papilla
- Minor calyx
- Major calyx
- Renal pelvis
- Ureter
- Urinary bladder
Function of ureters
Propel urine by peristalsis, hydrostatic pressure, and gravity
Micturition
detrusor muscle contracts and forces urine out of bladder
Urination
internal/external urethral sphincters relax to allow passage of urine (internal-involuntary, external-voluntary)
How many urethral sphincters do males and females have?
Male: 2 external and internal
Female: 1 external
Ureteral
has to do with ureters
Urethral
has to do with urethra
What makes up the male urethra?
Prostatic urethra
Membranous urethra
Spongy urethra
What is the function of the internal urethral sphincter?
prevent reflux of semen into bladder during ejaculation
What is the function of the external urethral sphincter?
voluntary control over voiding urine
How long is the female urethra?
3-4 cm
How long is the male urethra?
18 cm
Osmosis
water movement from area of low solute concentration to area of high solute concentration
Glomerular filtration
creates plasmalike filtrate of blood
Reabsorption
removes useful solutes from filtrate and returns to blood
tubule to blood
Secretion
removes additional wastes from the blood, adds them to filtrate
blood to tubule
What type of epithelium is in the glomerulus?
simple squamous (for filtration, easy passage of big molecules through)
What type of epithelium is in the proximal convoluted tubule?
Simple cuboidal with microvilli
What type of epithelium is in the thick segments of the nephron loop?
Simple cuboidal
What type of epithelium is in the distal convoluted tubule, collecting duct, and papillary duct?
simple cuboidal
What does the filtration membrane consist of?
Endothelium, basement membrane, and slit membrane (between pedicels)
Podocyte
simple squamous epithelial cells of glomerular capsule
Pedicels
fingerlike projections on podocytes that wrap around capillary endothelial cells
How does the filtration barrier filter blood?
filters molecules by their size and their charge
Glomerular filtration rate (GFR)
volume of filtrate formed in all renal corpuscles of both kidneys per minute
What affects GFR
blood pressure in glomerulus
afferent/efferent arteriole diameter
What does the proximal convoluted tubule do?
Reabsorption and Secretion
What does the Descending Limb of the Loop of Henle do?
permeable to H2o but not solutes
filtrate osmolarity increases as H2O leaves tubule
What does the ascending limb of the loop of Henle do?
permeable to solutes, less permeable to H2O
filtrate osmolarity decreases as solutes leave tubule (bring back to normal osmolarity)
What does the distal convoluted tubule do?
reabsorbs Na+ and Cl-, some H2O follows
filtrate is more dilute than when first filtered (because less substances in it)
Facultative water reabsorption
water reabsorption that can be directly controlled
ex water reabsorption increases in response to ADH
obligatory water reabsorption
uncontrolled water movement by osmosis
ex in PCT where water passively follows solute reabsorption
What function does Bowman’s capsule do?
filtration
What functions do the proximal and distal convoluted tubules do?
reabsorption and secretion
What function does the loop of henle do?
reabsorption
What functions does the collecting duct do?
some reabsorption