Urinary Embryology Flashcards

1
Q

What are the three parts of the urogenital sinus?

A

Vesicle part
Pelvic (middle) part
Phallic part

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does the vesicle part of the urogenital sinus form?

A

Urinary bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does the pelvic (middle) part of the urogenital sinus form?

A

Bladder neck and prostatic urethra in male

Entire urethra in female

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What does the phallic part of the urogenital sinus form?

A

Penile urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is formed by the mesonephric ducts incorporating into the posterior bladder wall?

A

Trigone of the bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the distal male urethra derived from?

A

Ectodermal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What embryonic tissue makes up the connective tissue and smooth muscle of the urinary bladder and urethra?

A

Splanchnic mesenchyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What developmental abnormality can result from partial failure of epithelial cell degeneration in the urachus?

A

Urachal cyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What developmental abnormality can result from failure of the umbilical urachus to close?

A

Urachal sinus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What developmental abnormality can result from a complete failure of the urachal duct to close?

A

Urachal fistula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What developmental abnormality can result from failure of mesenchymal cells migrating between ectoderm and cloaca?

A

Exstrophy of the bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What developmental abnormality can result from presence of posterior urethral valves in the bladder?

A

Megacystis or megalocystis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Who is megacystis most common in?

A

ONLY present in males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where is the urethral valve present in a case of megacystis?

A

Where ejaculatory ducts enter prostatic urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What gives rise to the adrenocortical primordia?

A

Cranial part of urogenital ridge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What gives rise to the adrenal medulla?

A

Neural crest cells

17
Q

What gives rise to the adrenal cortex?

A

Adrenocortical primordia (from cranial part of urogenital ridge)

18
Q

What tissue makes up the fetal adrenal cortex?

A

Mesoderm

19
Q

What part of adrenal tissue is very large in a neonate?

A

Cortex

20
Q

What eventually replaces the fetal cortex?

A

Mesenchymal cells

21
Q

What is defective in adrenogenital syndrome?

A

21-hydroxylase (Cytochrome P450-C21)

22
Q

What is overproduced in adrenogenital syndrome?

A

Androgens

ACTH

23
Q

What happens in female sexual organ development due to adrenogenital syndrome?

A

Masculinization of external genitalia

24
Q

What happens to both males and females in childhood with adrenogenital syndrome?

A

EARLY rapid growth and skeletal muscle maturation