Urinary Casts

Question 0

RBC Casts

Seen In (4)?

Answer 0

SEEN IN:

• Glomerulonephritis
• Ischemia
• Malignant Htn
• Wegener Granulomatosis

Question 1

Urinary Casts

Significance?

Answer 1

Presence of urinary casts indicates that hematuria / pyuria is of RENAL (vs bladder) origin.

Question 2

WBC Casts

Seen In (3)?

Answer 2

SEEN IN:

• Acute Pyelonephritis
• Tubulointerstitial Inflammation
• Transplant Rejection

Question 3

Eosinophilic Casts (resembling thyroid tissue)

Seen In?

Answer 3

SEEN IN:

- Chronic Pyelonephritis (“Thyroidization” of kidney)

Question 4

Fatty Casts (“oval fat bodies”)

Def’n, Seen In?

Answer 4

Dead PCT cells loaded with lipids (from lipid catabolism in PCT).

SEEN IN:
- Nephrotic Sx

Question 5

Granular Casts (“muddy brown”)

Answer 5

SEEN IN:

- Acute Tubular Necrosis / INTRINSIC Acute Renal Failure

Question 6

Hyaline Casts

Answer 6

Nonspecific. Can be a normal finding, often seen in concentrated urine samples.

Question 7

Renal Epithelial Casts

Significance, Seen In?

Answer 7

Signify tubular damage.

SEEN IN:
- Acute viral or toxic renal injury

Question 8

Waxy Casts (accompanied by very low urine flow)

Seen In (2)?

Answer 8

SEEN IN:

• Advanced renal disease
• Chronic Renal Failure