Skin Flashcards
Angioma
Def’n, Seen In?
Benign tumor derived from cells of vascular or lymphatic vessel walls (epithelium) or from cells / tissue surrounding vessels.
SEEN IN:
- Sturge-Weber Sx (leptomeningeal angiomas)
Angiokeratoma
Def’n, Seen In?
Cutaneous lesion of dilated capillaries ->
Small red-purple raised spots.
SEEN IN:
- Fabry dz (Lysosomal Storage dz)
Auspitz Sign
Def’n, Cause, Seen In?
Pinpoint bleeding spots.
CAUSE: Exposure of dermal papillae when scales are scraped off
SEEN IN:
- Psoriasis
Acantholysis
Location Affected, Def’n / Pres, Seen In?
Skin + Oral mucosa.
Intraepidermal bullae causing flaccid blisters.
SEEN IN:
- Pemphigus Vulgaris
Hyperpigmentation
Mech, Seen In?
MECH = ↑MSH
SEEN IN:
- Addison’s (↑MSH due to ↑ACTH)
Nikolsky’s Sign
Def’n, (Positive) Seen In?
Separation of epidermis upon manual stroking of skin.
+ SEEN IN:
- Pemphigus Vulgaris
Xanthomas
Location Affected (MC), Def’n, Seen In (3)?
MC in Eyelids (= Xanthelasma)
Yellowish plaques / nodules in skin composed of lipid-laden histiocytes in skin.
SEEN IN:
- I-hyperchylomicronemia (“eruptive / pruritic” xanthomas)
- Hyperlipidemia
- Biliary Tract Obstruction / Obstructive Jaundice
NEURO
Adenoma Sebaceum
Def’n, Seen In?
Raised erythematous papules on face, esp around nose.
SEEN IN: Tuberous Sclerosis
NEURO
Ash-Leaf Spots
Def’n, Seen In?
Hypomelanic / hypopigmented patches of skin. Anywhere on body.
SEEN IN:
- Sturge-Weber Sx
NEURO
Cafe-au-Lait Spots
Def’n, Seen In (2)?
Brown lesions with either smooth or irregular borders.
SEEN IN:
- Neurofibromatosis Type 1
- McCune-Albright Sx
NEURO, CV
Port-Wine Stains (nevus flammeus)
Def’n, Distribution, Seen In?
Hemangioma / birthmark in which swollen blood vessels create a REDDISH-PURPLISH discoloration of skin.
DISTR: V1 + V2 distr of trigeminal nerve
SEEN IN:
- Sturge-Weber Sx
MSK
Butterfly / Malar Rash
Def’n, Seen In (2)?
Rash involving nose + cheeks.
SEEN IN:
- SLE
- Dermatomyositis
MSK, GI
Erythema Nodosum
Location Affected, Def’n, Seen In?
Shins.
Infl of fat cells under skin -> tender red lumps on Shins.
SEEN IN:
- IBD
GI
Pyoderma Gangrenosum
Seen In?
SEEN IN:
- IBD
ENDO
Generalized Hyperpigmentation
SEEN IN: Addison Disease