Skin Flashcards

1
Q

Angioma

Def’n, Seen In?

A

Benign tumor derived from cells of vascular or lymphatic vessel walls (epithelium) or from cells / tissue surrounding vessels.

SEEN IN:
- Sturge-Weber Sx (leptomeningeal angiomas)

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2
Q

Angiokeratoma

Def’n, Seen In?

A

Cutaneous lesion of dilated capillaries ->
Small red-purple raised spots.

SEEN IN:
- Fabry dz (Lysosomal Storage dz)

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3
Q

Auspitz Sign

Def’n, Cause, Seen In?

A

Pinpoint bleeding spots.

CAUSE: Exposure of dermal papillae when scales are scraped off

SEEN IN:
- Psoriasis

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3
Q

Acantholysis

Location Affected, Def’n / Pres, Seen In?

A

Skin + Oral mucosa.

Intraepidermal bullae causing flaccid blisters.

SEEN IN:
- Pemphigus Vulgaris

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4
Q

Hyperpigmentation

Mech, Seen In?

A

MECH = ↑MSH

SEEN IN:
- Addison’s (↑MSH due to ↑ACTH)

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5
Q

Nikolsky’s Sign

Def’n, (Positive) Seen In?

A

Separation of epidermis upon manual stroking of skin.

+ SEEN IN:
- Pemphigus Vulgaris

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6
Q

Xanthomas

Location Affected (MC), Def’n, Seen In (3)?

A

MC in Eyelids (= Xanthelasma)

Yellowish plaques / nodules in skin composed of lipid-laden histiocytes in skin.

SEEN IN:

  • I-hyperchylomicronemia (“eruptive / pruritic” xanthomas)
  • Hyperlipidemia
  • Biliary Tract Obstruction / Obstructive Jaundice
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7
Q

NEURO

Adenoma Sebaceum

Def’n, Seen In?

A

Raised erythematous papules on face, esp around nose.

SEEN IN: Tuberous Sclerosis

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8
Q

NEURO

Ash-Leaf Spots

Def’n, Seen In?

A

Hypomelanic / hypopigmented patches of skin. Anywhere on body.

SEEN IN:
- Sturge-Weber Sx

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9
Q

NEURO

Cafe-au-Lait Spots

Def’n, Seen In (2)?

A

Brown lesions with either smooth or irregular borders.

SEEN IN:

  • Neurofibromatosis Type 1
  • McCune-Albright Sx
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10
Q

NEURO, CV

Port-Wine Stains (nevus flammeus)

Def’n, Distribution, Seen In?

A

Hemangioma / birthmark in which swollen blood vessels create a REDDISH-PURPLISH discoloration of skin.

DISTR: V1 + V2 distr of trigeminal nerve

SEEN IN:
- Sturge-Weber Sx

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11
Q

MSK

Butterfly / Malar Rash

Def’n, Seen In (2)?

A

Rash involving nose + cheeks.

SEEN IN:

  • SLE
  • Dermatomyositis
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12
Q

MSK, GI

Erythema Nodosum

Location Affected, Def’n, Seen In?

A

Shins.

Infl of fat cells under skin -> tender red lumps on Shins.

SEEN IN:
- IBD

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13
Q

GI

Pyoderma Gangrenosum

Seen In?

A

SEEN IN:

- IBD

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14
Q

ENDO

Generalized Hyperpigmentation

A

SEEN IN: Addison Disease

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15
Q

REPRO

Chancre

Def’n, Seen In?

A

PAINLESS ulcer, usually on genitalia.

SEEN IN: Primary Syphilis

16
Q

REPRO

Chancroid

Def’n + Chars (3), Seen In?

A

PAINFUL ulcer, usually on genitalia, with:

  • EXUDATE
  • Adenopathy
  • Slow to heal

SEEN IN: Haemophilus ducreyi infection

17
Q

REPRO

Conyloma Lata

Def’n, Seen In, Micro Findings?

A

PAINLESS smooth, flat, moist, white genital lesions.

SEEN IN: Secondary Syphilis

FINDINGS:
- Spirochetes (scrapings may show)

18
Q

REPRO

Vesicles (small + painful)

Seen In (2)?

A

SEEN IN:

  • Herpes
  • Dermatitis Herpetiformis
19
Q

MICRO

Rash on Palms + Soles

Seen In (3)?

A

SEEN IN:

  • Secondary Syphilis
  • Rocky Mountain Spotted Fever
  • Coxsackie A virus
20
Q

MICRO

Rash that starts centrally and spreads, SPARING palms + soles

Seen In?

A

SEEN IN: Rickettsii infections (wrists)

21
Q

MICRO

“Slapped cheek” rash on face

Seen In?

A

SEEN IN: Erythema Infectiosum (Parvo B19)

22
Q

MICRO

Erythema Chronicum Migrans

Def’n, Seen In?

A

Expanding red ring with central clearing (“target”) at tick bite site.

SEEN IN: Lyme Disease

23
Q

MICRO

Koplik Spots

Def’n, Seen In (2)?

A

Small red spots w blue-white centers on buccal / lingual mucosa.

SEEN IN:

  • Measles (Koplik Spots precede Measles rash by 1-2 days)
  • Rubeola virus
24
Q

MICRO

Facial / Oral Abscesses -> Drain thr sinus tracts

Causative Bug, Micro Finding (CLUE)?

A

Actinomyces.

FINDING = “yellow sulfur granules”

25
Q

MICRO

“Black necrotic eschar” on face

Seen In?

A

SEEN IN: Mucor + Rhizopus infections

26
Q

MICRO

“Blueberry muffin” rash

Seen In (2)?

A

SEEN IN:

  • Congenital Rubella (indicative of extramedullary hematopoiesis)
  • CMV
27
Q

MICRO, CV

Bacillary Angiomatosis

Def’n, Causative Bugs?

A

Benign capillary skin papules found in AIDS patients.
** Frequently mistaken for Kaposi Sarcoma **

Bartonella henselae

28
Q

MICRO, CV

Kaposi Sarcoma

Def’n, Locations Affected (4), Causative Bugs,
Pres (3 Epi + CLUE)?

A

Endothelial malignancy of skin.
** Frequently mistaken for Bacillary Angiomatosis **

  • Skin
  • Lymph nodes
  • Lungs
  • GI tract

HHV-8

PRES: AIDS patients, Transplant recipients,
Elderly Eastern-European Males.
- “Purple patches, plaques + nodules on skin / mouth”

29
Q

CV

Osler Nodes

Location Affected, Def’n, Mech, Seen In?

A

Pads of Digits.

PAINFUL raised red lesions on pads of fingers / toes.

MECH: Due to IC deposition

SEEN IN:
- Bacterial Endocarditis

30
Q

CV

Janeway Lesions

Location Affected, Def’n, Mech (2 options), Seen In?

A

Palms / Soles.

PAINLESS red lesions on palms / soles.

MECH:
- Microabscesses
OR
- Septic Emboli

SEEN IN:
- Bacterial Endocarditis

31
Q

CV

“Hand-Foot Erythema”

Seen In?

A

SEEN IN:

- Kawasaki Dz

32
Q

CV

Palpable Purpura

Seen In (3)?

A

SEEN IN: (Small-Vessel Vasculites)

  • Churg-Strauss Sx
  • Henoch-Schonlein Purpura (on “buttocks + legs”)
  • Microscopic Polyangitis
33
Q

CV

Erythema Marginatum

Locations Affected (2 MC), Def’n, Seen In?

A

MC on Trunk + Limbs

Rash with erythematous borders.

SEEN IN:
- Rheumatic Fever

34
Q

CV

Glomus Tumor

Def’n (incl CLUE), Origin?

A

Vascular tumor. Benign “painful red-blue tumor under fingernails”.

ORIGIN = modified smooth muscle cells of glomus body.
(Glomus Body = component of dermis involved in body temp regulation)

35
Q

BCEM

Elastic skin

A

SEEN IN: Ehlers-Danlos Sx

36
Q

BCEM

Dark Connective Tis

Seen In?

A

SEEN IN: Alkaptonuria / Ochronosis