Urea cycle

Question 1

urea cycle

in order

Answer 1

1. NH3 + CO2
2. Carbamoyl Phosphate (+Ornithine)
3. Citrulline (+Aspartate, ATP)
4. Argininosuccinate
5. Arginine (,fumarate)
6. Ornithine (,Urea)

Question 2

urea cycle catalysts

in order

Answer 2

1. CPS1
2. Ornithine Transcarbamylase
3. Argininosuccinate Synthesase
4. Arganinosuccinase

Question 3

site of occurence of urea cycle

Answer 3

1. (hepatic) mitochondria
2. cytoplasm

Question 4

urea cycle

process in mitochondria

Answer 4

1. NH2+CO2
2. CPS1
3. CP
4. Ornithine
5. Ornithine Transcarbamoyl
6. Citrulline

Question 5

rate limiting enzyme

Answer 5

Carbamoyl Phosphate Synthesase1 (CPS1)

Question 6

Principle of:

Ornithine Transcarbamylase defficiency

Answer 6

• Ornithine Transcarbamylase ↓
• Citrulline ↓
• Carbamoyl phosphate ↑
• orotic acid ↑
• ammonia ↑