BioChem pt4 Flashcards

1
Q

referred to as the digestion of the naturally occurring foodstuff into absorbable forms

A

digestion

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2
Q

chemical breakdown of food (mouth)

chewing or mastication

A

mechanical digestion

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3
Q

chemical breakdown of food (mouth)

hydrolysis of starch by salivary amylase

A

chemical digestion

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4
Q

colorless, slightly viscid opalescent fluid which is a mixture of secretions of the three pais of salivary glands

A

saliva

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5
Q

factors influencing the secretion of saliva

A
  1. psychic
  2. chemical
  3. mechanical

sight, smell and taste of food

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6
Q

aka ptyalin

A

salivary amylase

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7
Q

chemical breakdown of food (stomach)

mainly concerned with the digestion of proteins through the action of the enzyme pepsin and HCl

A

gastric digestion

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8
Q

initiates protein digestion producing proteoses, peptones and polypeptides

A

pepsin

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9
Q

3 phases in gastric digestion

A
  1. psychic phase
  2. gastric phase
  3. intestinal phase
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10
Q

includes all processes by which noxious substances are rendered less harmful or more easily excreted

A

detoxification

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11
Q

enzymes in intestinal juice

A
  1. carbohydrates
  2. peptidases
  3. nucleotidases
  4. nucleosidases
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12
Q

combined secretion of the intestinal gland at different portions

A

intestinal juice

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13
Q

secreted by the acinar cells of the pancreas

A

pancreatic juice

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14
Q

regulation of pancreatic secretion

A
  1. vagal stimulation
  2. hormonal stimulation
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15
Q

enzymes in pancreatic juice

A
  1. trypsin
  2. chymotrypsin
  3. carboxypeptidase
  4. pancreatic amylase
  5. pancreatic lipase
  6. nucleodepolymerase
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16
Q

interchange of two gases between the body and its environment

A

respiration

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17
Q

organ of respiration

A

lungs

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18
Q

what has special affinity to oxygen

A

hemoglobin

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19
Q

unstable compound

A

oxyhemoglobin

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20
Q

Other Factors that increase the dissociation of oxyhemoglobin to hemoglobin and oxygen

A
  1. pH or hydrogen ion concentration
  2. temperature
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21
Q

Hysterical Hyperventilation

A

respiratory alkalosis

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22
Q

Abnormalities of Acid-Base Balance

A
  1. acidosis
  2. alkalosis
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23
Q

pneumonia, asthma, etc

A

respiratory acidosis

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24
Q

factors affecting the binding of enzyme kinetics

A
  1. energy
  2. molecular compatibility
  3. space availability
  4. specificity
25
factors affecting E and S combination
1. lock and key 2. induced fit model
26
refers to the active site being complementary in shape and size of the substrate
lock and key
27
refers to enzyme changing in shape during binding with substrate
induced fit model
28
factors influencing enzymatic reaction
1. substrate concentration 2. time 3. enzyme concentration 4. temperature 5. pH 6. activators 7. inhibitors 8. coenzyme concentration 9. prosthetic group
29
2 phases of enzyme reaction
first order kinetics zero order kinetics
30
enzyme concentration is fixed and the substrate concentration is varied
first order kinetics
31
the rate depends on the enzyme concentration and independent of substrate concentration
zero order kinetics
32
increase reaction rate for every 10°C increase
Q10 value
33
an inhibitor competing with the natural or real substrate
competitive
34
inhibitor that has a change in shape
non-competitive
35
inhibitor with no product developed
uncompetitive
36
types of inhibition
1. reversible inhibition 2. irreversible inhibition
37
when inhibitors are possible removed from the system and enzyme is fully restored
reversible inhibition
38
when inhibitors combine covalently with the enzyme
irreversible inhibition
39
it refers to the disruption of the structure of enzyme molecule that leads to the loss of enzyme activity
enzyme denaturation
40
units of measurement
1. international unit (IU) 2. Katal
41
deficiency in dietary protein
kwashiorkor
42
slow starvation
marasmus
43
abnormal reduction in rbc
anemia
44
faulty metabolism in uric acid
gout
45
absence of enzyme phenylalanine hydroxylase
phenylketonuria
46
absence of tyrosinase
albinism
47
absence of homogentisic acid
alkaptonuria
48
hydroxyphenylacetic acid
tyrosinosis
49
bleeding disorder in which the blood does not clot properly
hemophilia
50
a condition in which a baby is born with an extra chromosome number 21
down syndrome
51
normal pH ratio
7.4
52
sugar components of dna and rna
DNA: deoxyribose RNA: ribose
53
pyrimidine bases of dna and rna
DNA: 1. cytosine 2. thymine RNA: 1. cytosine 2. uracil
54
color tests
1. fuelgen test 2. dische test 3. orcinol test 4. aniline
55
dna - red rna - negative
fuelgen test
56
dna - blue rna - negative
dische test
57
dna - negative rna - green
orcinol test
58
dna - red rna - negative
aniline
59
fat soluble vitamins
Vitamins A, D, E, K