Unit 7 Review Flashcards
What is Extemporaneous Compounding?
The process of making a specific compound when commercially available products are nots available.
What are the requirements in compounding hazardous drugs?
Must be done in a contained and ventilated room
Plastic backed mats must be placed on counter during preparation
Equipment must be dedicated to hazardous medication only
Sink available for handwashing
Eyewash station must be readily available
What is the Food and Drug Administration Act of 1997?
Made it allowable for pharmacies to compound non-sterile products for individual patients.
What is listed in USP <795>?
Guidelines to control good compounding practices
What are the 3 categories of compounding products?
Simple, Moderate, Complex
What is the description of simple compounding products?
Prep is listed in USP monographs or appear in peer-reviewed journal with specific instruction on preparation
What is the description of Moderate compounding products?
Preps that require special calculations or procedures to measure quantities. Include preps where stability data is not available.
What is the description of Complex compounding products?
Preparations that require special training, equipment, facilities or procedures. Includes Transdermal or modified-release preparations.
What is a Class III Torsion Balance?
Known as a Class A torsion balance. Two-pan balance, measures 15 to 120 grams, No less than 120mg should be weighed, Sensitivity requirement is +/- 6mg
What is a counterbalance?
Type of two-pan balance, use to weigh large amount of ingredients and bulk materials, weighs upto 5000g, sensitivity requirement is +/- 100mg
What is the use of the pharmaceutical Brass weight sets?
Used with two-pan balances in measuring and calibrating balances
What is a digital electronic scale?
Has one pan, more accurate than 2-pan, needs to be calibrated, needs to be leveled, uses lid to prevent drafts from altering the reading
What is weighing paper?
A paper used to weigh ointments, creams, or powders. Easier to scrape of paper than scale and protects ingredients from metal.
What is a plastic weighing boat?
Used to weigh larger amounts of creams, ointments, or powders
What is an ointment slab?
A nonporous surface used to mix ointments or creams
What are the different types of mortar and pestles and their uses?
Glass mortar and pestle
-Liquid preps, oily chemicals, or chemicals that stain
-Used for chemotherapy agents
Procelain and ceramic mortar and pestle
-Used to blend powders in or pulverizing soft materials and crystals
Wedgewood mortar and pestle
-Best for reducing the size of dry crystals and hard powder particles
Electric mortar and pestle
-Used for mixing, but not to reduce particle size
What is Comminution?
Reducing a substance to fine particles
What is Trituration?
Process of rubbing, grinding, or pulverizing a substance to create fine particles, usually in a mortar or pestle.
What is Levigation?
Process of reducing particle size of a solid when combining it with a cream or an ointment
What is a levigation Agent?
A liquid that makes mixes with a usually insoluable or undissolvable solid to make a paste that can mix into a cream or ointment. Common levigating agents are castor oil, glycerin, and mineral oil.
What is pulverization?
The process of reducing particle size of a solid by using a solvent. Common solvents are camphor, alchohol, iodine, and ether. Solvent evaporates and doesn’t become part of the final compound.
What is blending?
Combining two substances together
What is Spatulation?
Mixing ingredients with a spatula, also called folding, gentler than stirring provides a smooth uniform mixure.
What is sifting?
Process of combining two powders together
What is tumbling?
Process of combing two hazardous powders together by using a resealable bag or bottle.