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RATs > Unit 5:The Mouse > Flashcards

Unit 5:The Mouse Flashcards

1
Q

genus species of mouse

A

mus musculus (Mus=theif)

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2
Q

organ used in mice to detect pheromones, located in roof of mouth

A

vomeronasal organ (Jacobsons organ)

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3
Q

what is brown fat

A

hibernation fat, has increased blood flow for warmth

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4
Q

spot behind eye which we can draw blood from

what is this called in rats?

A

orbital sinus

rats= retro-orbital plexus

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5
Q

what is barbering

A

when dominant mouse pulls hair from face and body of other mice

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6
Q

when female mice develop nipples

A

9 days old

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7
Q

how many pairs of nipples females have

A

5

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8
Q

why rodents mice commonly get abdominal hernias

A

have an open inguinal canal which allows the spermatic cord to pass thro

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9
Q

whitten effect

A

group of females synchronize estrus cycles in presence of male

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10
Q

bruce effect

A

recently bred females may abort pregnancy when exposed to strange male (usu w/in 4 days of breeding)

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11
Q

what may cause cannibalism of neonates in mice

A

high-pitched sounds, little nesting material, and if disturbed; you should leave then 2 days undisturbed, preferably a week

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12
Q

what is the “milk spot” on neonate mice

A

see full stomach on left side of abdomen in healthy mice

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13
Q

how are nude mice produced? what research are they useful in

A

occur naturally (genetic defect), have deficient immune systems therefore useful in immune studies and cancer research

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14
Q

how to diagnose pinworm

A

do take prep on perianal region

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15
Q

what causes tyzzers

A

poor sanitation, overcrowding, stress

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16
Q

why tyzzers is hard to get rid of

A

produce spores, gram neg

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17
Q

what is Sendai virus

A

resp infection, compromises immune system, deadly

18
Q

what is ectromelia

A

mouse pox, affects v old and v young mice

19
Q

3 forms of ectromelia

A

acute- diarrhea, conjunctivitis, swelling of face and extremities, fatal
chronic- cutaneous rash leading to swelling and limb necrosis
Latent- older mice only, harbor in intestinal tract and spread (carriers)

20
Q

how to do intraperitoneal injection

diff between rat and mouse

A

anesthetize, scruff in dorsal recumb., point head towards floor, insert needle in lower right quadrant in mice (avoid spleen)
lower left in rats to avoid cecum

21
Q

why we do not withhold food before anesthetizing mice

A

fast metabolism, would go in shock

22
Q

mice (and rats) have __ digits on front feet __ digits on back

A

4 front, 5 back

23
Q

difference between galbladder in mice and rats

A

rats do not have, mice do

24
Q

mouse lifespan

A

12-36 months

25
Q

mouse dental formula

A

same as rat; I 1/1 C0/0 M3/3

26
Q

how long mouse gestation, how big are litters?

A

19-21 days (have ab 6-16 pups)

27
Q

weaning age in rats and mice

A

21days (18-21 in mice)

28
Q

what are hybrid mice

A

cross of 2 inbred strains

29
Q

how transgenic mice are created

A

inject DNA from one animal into fertilized egg of another

30
Q

what is murine colonic hyperplasia

A

a gram neg bacteria that causes explosive diarrhea, prolapsed rectum. treat w antibiotics

31
Q

signs of tyzzers

A

anorexia, dehydration, diarrhea

32
Q

how to restrain mice

A

grab base of tail, scruff, hold tail w pinkie finger

33
Q

a bubble of fluid under the skin is referred to as what

A

a bleb

34
Q

how to give SQ injection on mouse

A

scruff, allow it to hang onto cage w front paws, insert into tent base parallel to body

35
Q

how to draw blood from mouse tail

A

warm mouse, anesthetize, restrain, cut off up to 1 cm of tail tip, collect in hematocrit tube, cauterize or apply pressure

36
Q

list all blood collection options for mice

A

tail, jugular, dorsal pedal vein, orbital sinus, facial vein

37
Q

how to do facial and dorsal pedal vein blood collection

A

nick vein

38
Q

how to collect blood from orbital sinus is mice

A

anesthetize, stick hematocrit tube in lateral canthus at 45 degree angle

39
Q

most humane euthanasia method

A

OD of isoflurane (other methods the same as rat methods)

40
Q

Age mice become sexually mature

A

6 weeks

RATs (16 decks)

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