Unit 4 Topic 1 Flashcards

1
Q

Capsule

A

outer layer of connective tissue

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2
Q

Cortex

A

outer region containing glomeruli

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3
Q

Medulla

A

inner region containing renal pyramids

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4
Q

Lobe

A

pyramid + associated cortical tissue adjacent

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5
Q

Lobule

A

cortical labyrinth and central medullary ray

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6
Q

Cortical Labyrinth

A

area with glomeruli and closest tubule

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7
Q

Central medullary artery

A

area with only renal tubules

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8
Q

Glomerulus

A

high pressure capillary

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9
Q

Glomerular/Bowman’s capsule

A

structrual support surrounding the glomerulus

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10
Q

Glomerular/Bowman’s Space

A

collects filtrate

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11
Q

What is the sequence of the renal tubule?

A

proximal convoluted tubule–>Nephron Loop–>Collecting Duct

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12
Q

Sequence the Nephron Loop

A

Descending thick–>Descending Thin–>Ascending Thin–>Ascending Thick

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13
Q

What cells line the proximal convoluted tubule?

A

simple columnar epithelium

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14
Q

What cells line the descending thick segment?

A

simple cuboidal epithelium

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15
Q

What cells line the descending thin segment?

A

simple squamous

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16
Q

What cells line the ascending thin segment?

A

simple squamous

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17
Q

What cells line the ascending thick segment?

A

simple cuboidal

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18
Q

What cells line the distal convoluted tubule?

A

simple cuboidal epithelium

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19
Q

What cells line the collecting duct?

A

simple cuboidal epithelium

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20
Q

What makes up 85% of nephrons?

A

cortical nephrons

21
Q

What makes up the majority of nephrons in the cortex?

A

cortical nephrons

22
Q

What makes up 15% of nephrons?

A

juxtamedullary

23
Q

What do the juxtamedullary nephrons dip into?

A

medulla

24
Q

What is the function of the juxtamedullary nephron?

A

concentrates urine

25
Q

What capillaries follow convoluted tubules?

A

peritubular capillaries

26
Q

What type of capillary is found in the cortex?

A

peritubular

27
Q

What type of capillary is found primarily in the medulla?

A

vasa recta

28
Q

What does the vasa recta capillary follow?

A

nephron loop of juxtamedullary nephrons

29
Q

What are the components of the filtration membrane?

A

fenestrated epithelium, basal lamina, and podocyte

30
Q

What is the purpose of the fenestrated epithelium?

A

allows solutes to pass, but not larger cells or large plasma proteins

31
Q

What is the purpose of the basal lamina in the filtration membrane?

A

repels negatively charged solutes/molecules because it is negatively charged

32
Q

What is the basal lamina of the filtration membrane made out of?

A

type III collagen

33
Q

What is the purpose of the podocyte in the filtration membrane?

A

foot processes create slit membranes that prevent filtration of medium-sized proteins

34
Q

What regulates what is released from blood using the filtration membrane?

A

glomerular filtration

35
Q

What removes substance from the blood and adds back to the tubules?

A

tubular secretion

36
Q

Does tubular secretion occur along the length of the tubule?

A

yes

37
Q

What removes substances from the tubules and adds back to the blood?

A

tubular reabsorbtion

38
Q

Does tubular reabsorbtion occur along the length of the tubule?

A

yes

39
Q

What is the function of the proximal convoluted tubule?

A

reabsorbtion

40
Q

What is the difference in the proximal convoluted tubule epithelium and distal convoluted tubule epithelium?

A

simple columnar in proximal; simple cuboidal in distal

41
Q

What is the function of the distal convoluted tubule

A

regulates K, Na, and NaCl

42
Q

What is the function of the juxtaglomerular apparatus?

A

maintains blood pressure and to act as a quality control mechanisim to endure proper glomerular flow rate and efficent sodium reabsorption

43
Q

What is the path of urine once it leaves the collecting duct?

A

collecting duct–>Ureter–>Bladder

44
Q

What does the descending limb of the nephron loop do to urine?

A

concentrates urine

45
Q

What does the ascending limb of the nephron loop due to urine?

A

dilutes urine

46
Q

What limb of the nephron loop is permeable to water and impermeable to solutes?

A

descending limb

47
Q

What limb of the nephron loop is impermeable to water and permeable to solutes?

A

ascending limb

48
Q

What removes solutes and water from the nephron loop to maintain the gradient?

A

vasa recta

49
Q

What is highly sensitive to hormones and uses the gradient?

A

collecting duct