Unit 2 Topic 2 Flashcards
What is the structure of an erythrocyte?
bioconcave disk shape cells
What makes up an erythrocyte?
-Cytoplasm: mature cells do not have organelles and contain mostley hemoglobin
-Membrane: glycolipids/proteins determine ABO blood type
What is the function of hemoglobin?
transports the oxygen that is bound to the heme group
What is the structure of a leukocyte?
larger than erythrocytes; all contain nonspecific azurophilic granules that are the equivalent of lysosomes
What is the structure of thrombocytes?
cell fragments from megakaryocyte
What makes up a thrombocyte?
contain alpha granules (clotting factors) and dense cores (histamine)
What is the function of a thrombocyte?
clot formation, binding injure blood vessel walls, aggregating RBCs, and hemostatic plug stops bleeding
What is erythropoiesis?
RBC production that begins in bone marrow
What is found in early erythropoiesis?
proerythroblast
What is found in intermediate erythropoiesis?
Basophillic erythroblast→Polychromatic erythroblast→normoblast
What is found in late erythropoeisis?
reticulocyte–>erythrocyte
What is thrombopoesis?
platelet production; begins in bone marrow
What is the process of thrombopoeisis?
-Megakaryocytes come from megakaryoblasts, which come from the megakaryocyte progenitor cells
-The cells cytoplasm will fragment and become platelets with granules
-The nuclei remain in the bone marrow and are broken down using apoptotic means
Bone Marrow Cords
active hematopoietic cells
Bone Marrow Sinusoids
contain mature RBCs that allow entrance of cells/platelets into the peripheral circulation
