Unit 3- Lower Urinary Tract Flashcards
Pathology of LUT
Obstruction or infection
Male Pathology
Obstruction due to urethral anatomy
Female Pathology
Infection due to short urethra
Ectopic Ureter
Most common ureteral anomaly, terminates at urethra or vagina, predisposes to ascending infection
Urolithiasis
Calculi in urinary passages
Calculi
Minerals predominate, form round hard structures
Urethral Plugs
Masses of sandy sludge with higher organic component
Dalmation Calculi
Urate from defective uric acid metabolism
Cystine Calculi
Defective proximal tubule resorption in dogs and cats
Calcium Oxalate Calculi
Caused by hyperparathyroidism and hypercalcemia
Ammonium biurate Calculi
Caused by severe liver disease or portosystemic shunts
Struvite Calculi
Caused by urease from staph or proteus, mostly in dogs
Most Predisposed to Calculi
Cattle, sheep, dogs, and ats
Dog Breeds Predisposed to Calculi
Dachshund, dalmation, cocker spaniel, basset hound, poodle, schnauzer, terriers
Cattle Urethral Calculi Site
At the ischial arch and proximal end of the sigmoid flexure
Ram Urethral Calculi Site
At the urethral process in the vermiform appendage
Dog Urethral Calculi Site
Proximal base of the Os penis
Cat Urethral Calculi Site
Entire urethra
Urethral Calculi Complications
Local pressure necrosis, ulceration of mucosa, acute hemorrhagic urethritis
Nephrolith
Large calculus in the kidney pelvis
Portosystemic Shunts
Fibrosis compresses portal vein and causes hypertension, new blood vessels form linking to the vena cava, and blood bypasses the liver so ammonia cannot be metabolized
Bacterial Cystitis
UPEC E coli mostly, some specific renal pathogens
Blister Beetle
Epicauta beetles in hay release Cantharidin and cause ulcerative cystitis in horses
Cyclophosphamide
Causes hemorrhagic cystitis in dog and cat
Feline Lower Urinary Tract Disease
Caused by idiopathic interstitial cystitis, infection, or urethral obstruction
FLUTD Risk Factors
Older, neutered, fat, little exercise, dehydration, stress
Follicular Cystitis
Disseminated submucosal lymphoid nodules
Polypoid Cystitis
Polys composed of connective tissue mixed with mononuclear cells
Emphysematous Cystitis
Air filled bullar in urinary mucosa, associated with Diabetes and glucosuria causing overgrowth of glucose fermenting bacteria
Transitional Cell Carcinoma
Most common neoplasm, occurs in bladder neck and trigone, high rate of metastasis to lymph nodes, lung, and bone
Bracken Fern Poisoning
Ptaquiloside causes transitional cell carcinoma, hemangioma, hemangiosarcoma in cattle
Transitional Cell Carcinoma Classigication
Papillary and infiltrating most common, papillary and non infiltrating, non papillary and non infiltrating, non papillary and infiltrating metastasizes most commonly
Transitional Cell Carcinoma Sequelae
Hydroureter and hydronephrosis