Unit 3- Hematopoietic System Flashcards
Lymphatic Circulation
Subcapsular sinuses, trabecular sinuses, medullary sinuses, efferent lymphatics, thoracic duct
Small Lymph Node Reaction Patterns
Lymphoid atrophy, lymph node degeneration, lymph node hypoplasia
Enlarged Lymph Node Reaction Patterns
Lymphoid hyperplasia and drainage, lymphadenitis, metastatic neoplasia, primary neoplasia
Lymphoid Hyperplasia
Response to antigen presentation or interleukins, local or generalized, draining site of local infection
Lymph Node Histology Structure
Capsule, germinal center, outer cortex, and inner cortex
Suppurative Lymphadenitis
Bacterial infection, Strep, Cornyebacterium, and Trueperella pyogenes
Granulomatous Lymphadenitis
Bacterial, viral, or fungal
Equine Lymphadenitis
Strangles caused by Strep equi in the retropharyngeal lymph node
Onion Skin Lymph Node in Sheep
Caseous lymphadenitis caused by Cornyebacterium pseudotuberculosis
Bovine Granulomatous Lymph Node
Mycobacterium bovis in mesenteric lymph node
Rhodococcus equi
Respiratory disease and enteric disease in foals causing lymphadenitis
Primary Neoplasias of LN
Lymphoma, plasma cell tumor, and histiocytic neoplasm
Metastatic Neoplasias of LN
Carcinoma, melanoma, mast cell tumor
Oral Melanoma
Aggressive and metastasize to lymph nodes and lungs
Hemosiderosis
Brownish discoloration observed in lymph nodes draining areas of hemorrhage
Anthracosis
Carbon particles retained by macrophages so medulla appears black
White Pulp of Spleen
Lymphoid follicles
Red Pulp of Spleen
Hematopoietic center
Bloody Spleen
Diffuse splenomegaly with bloody consistency, congestion, septicemia, or acute hemolytic anemia
Anthrax
Rapid post mortem autolysis and blood oozing from body orifices, do not perform post mortem
Meaty Spleen
Diffuse splenomegaly with firm consistency, neoplasia, septicemia, chronic hemolytic anemia, granulomatous disease, diffuse follicular hyperplasia
Tularemia
Francisella tularensis, rabbit fever causes systemic disease in cats, multifocal miliary white foci in spleen, lymph node, and liver
Nodular Bloody Spleen
Hematoma, hemangiosarcoma, incomplete contraction, acute infarct, nodular hyperplasia
Splenic Hemangiosarcoma
Most common malignant tumor in canine, leads to hemabdomen, poor prognosis, endothelial cells fill with blood
Classical Swine Fever
Hog cholera, pestivirus targets macrophage, endothelial, and epithelial cells causing hemorrhage in kidneys, splenic infarct, necrotizing tonsilitis, and ulcers
Turkey Egg Kidney
Ecchymosis of kidneys due to hog cholera
Nodular Meaty Spleen
Focal nodular hyperplasia, granuloma, abscess, neoplasia
Histiocytic Sarcoma
Interstitial dendritic cells in bernese mountain dogs, rottweilers, and retreivers, has local or disseminated form in hematopoietic areas
Siderotic Plaques
Incidental lesions of the spleen
Splenic Amyloidosis
Orange and waxy spleen
Thymus Structure
Epithelial and lymphoid tissue, lobulated and split into cortical and medullary areas
Severe Combined Immunodeficiency
Arabian foals lack B and T lymphocytes, develop disease after a few days, atrophy of the thymus
Thymic Lymphoma
Neoplasm of T-lymphocytes in younger animals, malignant
Thymoma
Neoplasm of epithelial cells, less common, slow growing and encapsulated
Tonsil Reaction Patterns
Lymphoid depletion, inflammation, inflammatory polyps, neoplasia
Tonsil Lymphoid Depletion
Viral infections like classical swine fever
Tonsil Inflammation
Only primary or hematogenous, tonsils lack afferent lymphatics
Tonsil Inflammatory Polyps
Common in older dogs
Tonsil Neoplasia
Primary only, tonsils lack afferent lymphatics