UNIT 3 - Handout (Anatomy of Special Senses) Flashcards
special senses
- smell
- taste
- hear
- vision
- equilibrium
Neural pathways for the special senses are also MORE COMPLEX than those for the general senses.
As with general senses, physiologic processes of these special senses also involve detection of environmental stimuli and conversion of these stimuli to signals that the brain can interpret.
occupies the superior part of the nasal cavity, covering the inferior surface of the cribriform plate and extending along the superior nasal concha
olfactory epithelium
3 KINDS OF CELLS OF OLFACTORY EPITHELIUM
- olfactory receptor cells
- supporting cells
- basal cells
- First-order neurons of the olfactory pathway
- Bipolar neuron with an exposed knob shaped dendrite
- Axon projecting through the cribriform plate that ends in the olfactory bulb
a. _________: non-motile, site of olfactory transduction
b. _________: within cilia detecting odorants
- OLFACTORY RECEPTOR CELLS
a. olfactory cilia
b. olfactory receptors
- _______________ of the mucous membrane lining the nose.
- Provide physical support, nourishment, and electrical insulation for the olfactory receptor cells
- Help detoxify chemicals that come in contact with the olfactory epithelium
- SUPPORTING CELLS
- columnar epithelial cells
- Stem cells located between the bases of the supporting cells
- Continually undergo cell division to produce new olfactory receptor cells, which live for only a month or so before being replaced
basal cell
- found within the connective tissue that supports the olfactory epithelium
- Produce mucus that is carried to the surface of the epithelium by ducts
- Secretion moistens the surface of the olfactory epithelium and dissolves odorants so that transduction can occur.
olfactory glands (bowman’s glands)
- parasympathetic neurons within branches of the facial (VII) nerve
- Impulses in these nerves in turn stimulate the _______ glands in the eyes and nasal mucous glands
innervation of olfactory glands and supporting cells
- lacrimal
- react to odorant molecules in the same way that most sensory receptors react to their specific stimuli: a ________ (______) develops and triggers one or more nerve impulses.
This process, called ____________, occurs in the following way: Binding of an odorant to an olfactory receptor protein in an
olfactory cilium stimulates a membrane protein called a _________.
- The G protein, in turn, activates the enzyme __________ to produce a substance called ______________.
- The cAMP opens a sodium ion (Na+) channel that allows Na+ to enter the cytosol, which causes a depolarizing generator potential to form in the membrane of the olfactory receptor cell.
- If the depolarization reaches threshold, an action potential is generated along the axon of the olfactory receptor cell.
OLFACTORY RECEPTOR CELLS
- generator potential (depolarization)
- olfactory transduction; G protein
- adenylate cyclase; cyclic adenosine monophosphate (cAMP).
-
__________: reduced ability to smell, affects half of those over age 65 and 75% of those over age 80.
- also can be caused by neurological changes, such as a head injury, Alzheimer’s disease, or Parkinson’s disease; certain drugs, such as antihistamines, analgesics, or steroids; and the damaging effects of smoking.
hyposmia
- where receptors for sensation of taste are located
- Most of the nearly 10,000 taste buds of a young adult are on the tongue, but some are found on the ________ (posterior portion of the roof of the mouth), ________ (throat), and ________ (cartilage lid over voice box).
- The number of taste buds declines with age.
TASTE BUDS
- soft palate
- pharynx
- epiglottis
3 KINDS OF EPITHELIAL CELLS
- supporting cells
- gustatory receptor cells
- basal cells
- Contains microvilli and surround 50 gustatory receptor cells in each taste bud
supporting cells
- Life span of about 10 days
- ___________ (gustatory hairs) project from each gustatory receptor cell to the external surface through the taste pore, an opening in the taste bud
gustatory receptor cells
- Gustatory microvilli
- Stem cells found at the periphery of the taste bud near the connective tissue layer, produce supporting cells, which then develop into gustatory receptor cells.
basal cells
- elevations on the tongue where taste buds are found increase the surface area and provide a rough texture to the upper surface of the tongue
3 TYPES
PAPPILAE
- circular vallate papillae (wall-like) or circumvallate papillae
- fungiform papillae (mushroom-like)
- foliate papillae (leaflike)
- Form an inverted V-shaped row at the back of the tongue
- About 12 very large papillae
- Each of these papillae houses 100–300 taste buds.
CIRCULAR VALLATE PAPILLAE (WALL-LIKE) or CIRCUMVALLATE PAPILLAE
Mushroom-shaped elevations scattered over the entire surface of the tongue that contain about five taste buds each
FUNGIFORM PAPILLAE (MUSHROOM-LIKE)
Located in small trenches on the lateral margins of the tongue, but most of their taste buds degenerate in early childhood
FOLIATE PAPILLAE (LEAFLIKE)
- Contain tactile receptors but no taste buds.
- increase friction between the tongue and food, making it easier for the tongue to move food in the oral cavity.
filiform papillae (threadlike)
(1)
Chemicals that stimulate gustatory receptor cells are known as ________.
Once it is dissolved in saliva, it can make contact with the plasma membranes of the _______, which are the sites of taste transduction.
The result is a receptor potential that stimulates exocytosis of _________ from the release of neurotransmitter.
The hydrogen ions (H+) in sour tastants may flow into gustatory receptor cells via H+ channels.
- tastants
- gustatory microvilli
- ## synaptic vesicles
(2)
- also influence opening and closing of other types of ion channels.
- Again, the result is _______ & _______of neurotransmitter.
- Other tastants, responsible for stimulating sweet, bitter, and umami tastes, DO NOT themselves enter gustatory receptor cells.
- rather, they BIND to receptors on the plasma membrane that are linked to G proteins.
- The G proteins then activate several different chemicals known as _________ inside the gustatory receptor cell.
- Different second messengers cause depolarization in different ways, but the result is the same—_____________
- depolarization and the liberation
- second messengers
- release of neurotransmitter
If all tastants cause release of neurotransmitter from many gustatory receptor cells, why do foods taste different?
- answer is thought to lie in the patterns of nerve impulses in groups of first-order taste neurons that synapse with the gustatory receptor cells.
- Different tastes arise from activation of different groups of taste neurons.
- although each individual gustatory receptor cell responds to more than one of the five primary tastes, it may respond more strongly to some tastants than to others.