UNIT 1 - Human Anatomy, Physiology, and Pathophysiology Flashcards
- study of structure of organisms and their parts
- focuses on the physical arrangement and relationship between different body parts
ANATOMY
scopes of anatomy
- MACROSCOPIC (GROSS) ANATOMY
- MICROSCOPIC ANATOMY
branch of anatomy that looks at body parts visible to the naked eye
macroscopic anatomy
branch of anatomy that examines cells and tissues at the microscopic level
microscopic anatomy
examples: studying the structure of the heart, bones, muscles and organs
ANATOMY
- study of the functions and processes of living organisms and their parts
- explains how the body’s systems work and how they respons to challenges
PHYSIOLOGY
scope of physiology
- cellular physiology
- organ physiology
- systemic physiology
- pathophysiology
examples: understanding how the heart pumps blood, how muscles contract, and how the kidneys filter waste
physiology
- study of diseases, their causes, processes, development, and consequences
- aims to understand how and why diseases occur and how they affect the body
PATHOLOGY
scope of pathology
- General Pathology
- Systemic Pathology
the study of disease processes affecting multiple organs
general pathology
study of diseases affecting specific organ systems
systemic pathology
examples: examining tissue samples to diagnose cancer, understanding the progression of infectious diseases
pathology
- study of the physiological processes associated with disease or injury
- focuses on the changes in normal physiological functions caused by disease conditions
PATHOPHYSIOLOGY
scope of pathophysiology
- combined aspects of physiology and pathology to understand the mechanisms of disease at the functional level
examples: investigating how heart disease affects blood flow, how diabetes impacts insulin production and glucose metabolism
PATHOPHYSIOLOGY
refers to the framework or model used to understand and explain the causes, progression and treatment of diseases
disease paradigm
types of disease paradigms
- biomedical paradigm
- naturalistic or holistic paradigm
- magico-religious paradigm
- epidemiological paradigm
- theoretical and analytical paradigm
- most widely accepted model in contemporary healthcare
- focuses on biological factors and views the body as a machine that can be fixed when something goes wrong
- diseases are seen as having specific causes, such as bacteria, viruses, or genetic mutations
biomedical paradigm
- considers the balance of natural forces and the whole person, including physical, psychological, social and spiritual aspects
- ______ and ______ are examples of holistic approaches that emphasize harmony and balance
- traditional chinese medicine (TCM) and ayurveda
NATURALISTIC OR HOLISTIC PARADIGM
- attributes illness to supernatural forces or divine intervention
- practices such as ______, ______, and the use of ______, or _______ are common in this view
- prayer, rituals, charms or amulets
MAGICO-RELIGIOUS PARADIGM
- focuses on the patterns, causes, and effects of health and disease conditions in defines population
- involves studying the distribution and determinants of health-related states and applying this knowledge to control health problems
epidemiological paradigm
- newer approach which uses concepts from various fields like physics, mathematics, and economics to understand health and disease
- aims to uncover fundamental principles that govern biological systems and disease processes
theoretical and analytical paradigm
- also known as _______
- microorganisms or substances that cause disease or illness in their hosts
- causative agents
etiologic agents of disease
TYPES OF ETIOLOGIC AGENTS OF DISEASE
- infectious agents
- genetic factors
- environmental factors
- lifestyle factors
- autoimmune conditions
- physical agents
- INFECTIOUS AGENTS (5)
A. BACTERIA
B. VIRUSES
C. FUNGI
D. PARASITES
E. PRIONS
bacteria (2)
- Streptococcus pneumoniae
- causes pneumonia - Mycobacterium tuberculosis
- causes tuberculosis
viruses (2)
- Influenza virus
- causes flu - Human immunodeficiency virus
- HIV, causes AIDS
fungi (2)
- Candida albicans
- causes candidiasis - Aspergillus species
- causes aspergillosis
parasites (2)
- Plasmodium species
- causes malaria - Giardia lamblia
- causes giardiasis
prions
abnormal proteins causing diseases like Creutzfeldt-Jakob disease
- GENETIC FACTORS (2)
A. Inherited Genetic Disorders
- cystic fibrosis
- sickle cell anemia
- hemophilia
B. Mutations
- BRCA1 / BRCA2 mutations increasing breast cancer risk
- mutations causing Huntington’s disease
- ENVIRONMENTAL FACTORS (3)
A. TOXINS
- lead poisoning
- mercury poisoning
B. POLLUTION
- air pollution causing respiratory diseases
- water contamination (gastrointestinal infections)
C. RADIATION
- ultraviolet radiation causing skin cancer
- ionizing radiation exposure increasing cancer risk
- LIFESTYLE FACTORS (3)
A. DIET
- poor nutrition: malnutrition or obesity-related diseases
B. PHYSICAL ACTIVITY
- sedentary lifestyle: cardiovascular diseases
C. SUBSTANCE USE
- smoking: lung cancer, alcohol abuse —> liver cirrhosis
- AUTOIMMUNE CONDITIONS
Autoimmune diseases:
- rheumatoid arthritis
- lupus
- multiple sclerosis
- PHYSICAL AGENTS (2)
A. TRAUMA
- injuries: fractures
- concussions
B. TEMPERATURE EXTREMES
- frostbite
- heatstroke
refers to the progression of a disease process in an individual over time, in the absences of treatment
natural history of disease
5 stages of natural history of disease
- susceptibility
- incubation
- prodromal
- acute
- convalescence
5 stages
- exposure and infection
- incubation period
- prodromal period
- clinical stage
- recovery, disability, or death
the individual comes into contact with the disease-causing agent
exposure and infection
time between exposure and the onset of symptoms
incubation period
initial, mild symptoms may appear
prodromal period
the disease manifest with full-blown symptoms
clinical stage
depending on the disease and treatment, the individual may recover, live with chronic conditions, or, unfortunately, pass away
recovery, disability, or death