Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Unit 3-Anxiolytics > Flashcards

Unit 3-Anxiolytics Flashcards

1
Q

Diazepam

Class

A

Benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Diazepam

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 43 hours (active metabolites up to 100 hours)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Diazepam

Uses

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; anticonvulsant; muscle relaxant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diazepam

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Chlordiazepoxide

Class

A

Benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Chlordiazepoxide

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 10 hours (active metabolites up to 100 hours)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Chlordiazepoxide

Uses

A

Short-term depression treatment; maintenance of bipolar; severe bipolar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Chlordiazepoxide

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Lorazepam

Class

A

Benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Lorazepam

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 14 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Lorazepam

Uses

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; sedation; anticonvulsant; prevent withdrawal symptoms in alcoholics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lorazepam

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA; directly conjugated into inactive metabolite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Flurazepam

Class

A

Benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Flurazepam

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 74 hours (active metabolites up to 100 hours)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Flurazepam

Uses

A

Short-term depression treatment; maintenance of bipolar; severe bipolar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Flurazepam

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Alprozolam

Class

A

Benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Alprozolam

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 12 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Alprozolam

Uses

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; sedation

20
Q

Alprazolam

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA

21
Q

Midazolam

Class

A

Benzodiazepine

22
Q

Midazolam

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 1.9 hours

23
Q

Midazolam

Uses

A

Anesthesia (calming effects, production of anterograde amnesia)

24
Q

Midazolam

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA

25
Q

Triazolam

Class

A

Benzodiazepine

26
Q

Triazolam

Mechanism

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 2.9 hours

27
Q

Triazolam

Uses

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; induce sleep

28
Q

Triazolam

Side effects

A

Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)

“Ceiling effect” due to augmenting action of GABA

29
Q

Zolpidem

Class

A

Non-benzodiazepine receptor agonist

30
Q

Zolpidem

Mechanism

A

BDZ-1 selective agonist

31
Q

Zolpidem

Uses

A

Sedation and hypnosis without muscle relaxation or anticonvulsant activity

32
Q

Zolpidem

Side effects

A

Sleep-walking; next morning impairment

33
Q

Flumazenil

Class

A

Benzodiazepine antagonist

34
Q

Flumazenil

Mechanism

A

Competitive non-selective antagonist

35
Q

Flumazenil

Uses

A

Benzodiazapine overdose

36
Q

Flumazenil

Side effects

A

Withdrawal (may be life-threatening); seizures in mixed overdoses

Non uniform in reversal of respiratory depression

37
Q

Thiopental

Class

A

Barbiturate

38
Q

Thiopental

Mechanism

A

GABAa agonist (binds a or b subunit); highly lipid soluble, fast-on, fast-off

39
Q

Thiopental

Uses

A

Induce anesthesia

40
Q

Thiopental

Side effects

A

Daytime sedation and drowsiness, dose-dependent depression of CNS, pyschologic and physiologic dependence (chronic use)

Abrupt withdrawal life-threatening; redistribute from brain to muscle and fat, metabolized by liver; dosed based on lean body mass

41
Q

Phenobarbital

Class

A

Barbiturate

42
Q

Phenobarbital

Mechanism

A

GABAa agonist (binds a or b subunit)

43
Q

Phenobarbital

Uses

A

Antiepileptic, anticonvulsant

44
Q

Phenobarbital

Side effects

A

Daytime sedation and drowsiness, dose-dependent depression of CNS, pyschologic and physiologic dependence (chronic use)

Abrupt withdrawal life-threatening

45
Q

Buspirone

Mechanism

A

No GABAa interaction; may be partial agonist at 5HT1A

46
Q

Buspirone

Uses

A

Anxiolytic without marked sedation

Pharmacology (26 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions