Unit 3 Flashcards
Function of bone
- Support
- Movement
- Protection
- Mineral storage
Osteon
Structural unit of bone–a central canal surrounded by concentric circles of bone cells
Osteocytes
Bone cells
Osteoblast
Bone forming cell, mature into osteocytes
Epiphyseal plate
Layer of cartilage separating the shaft and the end of a bone. Cartilage cells in the plate divide, lengthening and increasing the diameter of the bone. Also called the growth plate.
Describe the formation of bone in a fetus.
- A cartilaginous model of the bone is formed.
- Osteoblasts form bone around the shaft of the model.
- The shaft begins to hollow and spongy bone replaces the cartilage.
- Bone begins to form in the center of the ends of the bone.
- Cartilage remains only on the ends of the bone and in the growth plate.
The functional units of compact bone.
Osteons
How does bone grow in childhood?
Cartilage cells in the growth plates divide when signaled by sex hormones and the extra cartilage is replaced with bone.
Where in a bone is fat stored?
Yellow bone marrow
A condition characterized by a decrease in bone density that causes a weakened bone.
Osteoporosis
What holds two bones together at a joint?
Ligaments
Bone is hardened by which two minerals?
Calcium and phosphorus.
Cells that form bones
Osteoblasts
What hormones are involved in bone growth?
Growth hormone signals liver to release growth factor
Thyroid hormone modifies growth hormone activity to regulate proportion of bone growth.
Sex hormones signal division of cartilage cells in growth plates.
What hormones are involved in the cessation of bone growth at puberty?
Sex hormones (testosterone and estrogen)
Where is growth hormone produced? What are the consequences of too much/too little growth hormone?
Growth hormone is produced in the anterior pituitary gland. Too little GH results in dwarfism. Too much GH results in giantism.
Why are people today taller on average than in the 1700s (assuming same genetic background)?
Nutrition
What hormones are involved in regulating plasma calcium concentration? Why is this regulation critical?
Calcitonin and parathyroid hormone.
Because low levels of plasma calcium concentration can lead to osteoporosis.
What is the role of vitamin D in bone health?
Vitamin D ensures efficient absorption of calcium.
Why is daily exposure to sunlight a good thing?
Sunlight allows our bodies to produce vitamin D.
How many calories are in one gram of protein? carbohydrate? fat?
Protein = 4 calories Carbohydrate = 4 calories Fat = 9 calories
How many excess calories does a person have to eat to gain one pound?
3500 calories.
celiac disease
A condition in which ingestion of gluten causes an autoimmune response. Damaging to villi in the digestive tract, which impairs nutrient absorption.
cholera
Bacterial infection in the small intestine resulting in diarrhea.
amoebic dysentery
Inflammation of the intestine causing diarrhea caused by amoeba.
gastric ulsers
A defect in the lining of the stomach
cirrhosis
An excess accumulation of fat around the liver due to excessive alcohol consumption, an excess of fat in the diet, or genetics.
hepatitis
Inflammation of the liver. Most commonly caused by a virus
polyp
A (usually) asymptomatic growth in the lining of the colon which can grow into colon cancer.
colonoscopy
A diagnostic test performed on the colon to look for polyps. Preventative of colon cancer.
BMI
Body Mass Index. Evaluates body weight relative to height.
Healthy: 18.5-25
Overweight: 25-30
Obese: <30
BMR
Basal Metabolic Rate. The minimum amount of energy needed to keep an awake, resting body alive.
What is the difference between a vitamin and a mineral?
A vitamin is an organic compound which is vital to health but needed in minute amounts.
A mineral is an inorganic compound vital to health. There are seven minerals needed in large doses and twelve needed in trace amounts.
What are the water-soluble vitamins?
What are the fat-soluble vitamins?
Water soluble vitamins: C and the various B vitamins
Fat soluble vitamins: A, D, E, K
What happens to excess amino acids in the body?
They are broken down by the liver.
essential amino acid
The nine amino acids which the body can’t synthesize.
essential fatty acid
Fatty acids which cannot be synthesized by the body. Omega-3 and Omega-6
saturated vs unsaturated fat
Unsaturated fats are liquid at room temperature and are usually from plant sources. Are considered healthier than saturated fats.
Saturated fats are solid at room temperature and are most often from animal sources. Supposedly linked to atherosclerosis.
cholesterol
A type of lipid. Essential in structure of cell membrane. Structural basis of the steroid hormones.
complementary proteins
Two sources of proteins that, when consumed together, provide all the essential amino acids.
malabsorption syndrome
A condition in which nutrients are not properly absorbed in the small intestine.
anorexia
A condition in which the person deliberately self-starves.
bulimia
A condition in which the person binge eats then purges by self-induced vomiting, enemas, laxatives, diuretics or excessive exercise.
GMO
Genetically Modified Organisms. Foods that have been genetically altered to produce a preferred trait. Highly controversial in regards to safety of consumption and effects on the environment, especially because few to no long-term safety studies exist.
What can urinalysis measure?
Abnormal constituents such as glucose, red blood cells, white blood cells which may indicate a health issue. Presence of abnormal levels of substances such as proteins. Presence of some drugs.
What are the three major areas of the kidney?
Renal cortex: outer region
Renal medulla: region enclosed by cortex
Renal pelvis: inner chamber
What are the functions of the kidney?
Produce urine Conserve water Regulate pH Stimulate red blood cell production Transform vit D to active form
How does the kidney help to maintain homeostasis?
They maintain salt and water balance by adjusting concentration of the urine.
What cell structure is shared in the lining of the proximal convoluted tubule and the lining of the small intestine? What is the common function of this cell structure?
Microvilli, which assist in absorption of substances.
What percent of the water that is filtered by the glomerulus is reabsorbed?
99%
What percent of the sodium that is filtered by the glomerulus is reabsorbed?
99%
What percent of the glucose that is filtered by the glomerulus is reabsorbed?
100%
How do diuretic medications help reduce blood pressure?
They increase the excretion of water by decreasing the reabsorption of sodium ions.
What are kidney stones?
Crystalized forms of certain substances (calcium, cystine, uric acid) in the kidney which may be painful if they pass through the kidney into the ureter.
What is metabolic waste?
Substances left over from the excretory processes which can’t be used by the body and must be excreted.
Why is electrolyte balance critical?
Because electrolytes are responsible for important bodily functions.
How does ADH affect the nephron and what is the effect of its action?
ADH regulates the amount of water reabsorbed by the collecting ducts. Increase in ADH results in increased water returned to the blood, which results in higher blood pressure.
How are the effects of atrial natriuretic hormone different from those of ADH and aldosterone?
ANH DECREASES the reabsorption of sodium ions. (Decreasing BP)
Aldosterone INCREASES the reabsorption of sodium ions. (Increasing BP)
ADH INCREASES reabsorption of water in the collecting ducts.
How is alcohol metabolized?
70% small intestine
20% stomach
10% excreted directly through urine/breath/sweat
Why does a breath sample indicate whether or not someone has consumed too much alcohol?
Because a portion of consumed alcohol is excreted directly through the breath.
What are the short term effects of heavy alcohol consumption or binge drinking?
Vomiting, impaired respiratory function, unconsciousness, coma.
What are the long term effects of excessive alcohol consumption?
Increased risk of cancer, liver damage, damage to the heart and blood vessels.