Unit 2 Infection Control Flashcards
Cycle of Infection
•Infectious organisms
•Reservoir of Infection
•Portal of exit
•Susceptible host
•Portal of entry
•Transmission of disease
Microorganisms capable of causing disease are called
pathogens or pathogenic organisms
Reservoir of Infection
•Place where pathogens can thrive in sufficient numbers to pose a threat
•Must have:
➢Moisture
➢Nutrients
➢Suitable temperature
•May be human or nonhuman (e.g., food, water, animals)
Portal of Exit and examples
Any route through which blood, body fluids, excretions, or secretions leave the body
•Examples:
➢GI tract
➢Open wound
➢Respiratory tract
Susceptible Hosts
•Patients are often hosts because of a reduced immune system.
•Nosocomial infection, also called HAI
➢hospital-acquired infection
➢health care-associated infection
•Healthcare workers are also at risk.
➢Exposure to blood and other bodily fluids
Nosocomial infection is a
hospital-acquired infection
Portal of Entry and examples
•The route by which microorganisms gain access into the susceptible host
•Examples:
➢Respiratory tract
➢Urinary tract
➢GI tract
➢Open wound or break in skin
➢Mucous membranes of the eyes, nose, or mouth
➢Bloodstream
Transmission of Disease
Most direct way to break the cycle of infection is to prevent transmission of the infectious organism from the reservoir to the susceptible host
Six main routes of transmission of disease
➢Direct contact
➢Fomites
➢Vectors
➢Vehicles
➢Airborne
➢Droplet contamination
Direct Contact and examples
•Infected person must touch susceptible host.
•Requires the pathogens to be placed in direct contact with susceptible tissue
•Examples:
➢Syphilis
➢HIV infections
➢Staph infections
Fomites and examples
•An object that has been in contact with pathogenic organisms
•Examples:
➢Contaminated gloves
➢X-ray table
➢Positioning sponges
Vectors and examples
•An arthropod in whose body an infectious organism develops or multiplies before becoming infective to a new host.
•Transmission occurs when an infected insect bites host.
•Examples:
➢Mosquitos—malaria
➢Ticks—Lyme disease
Vehicles and examples
•Any medium that transports microorganisms
•Examples:
➢Contaminated food, water, drugs, or blood
Droplet Contamination
Occurs when an infectious individual coughs, sneezes, speaks, or sings in the vicinity of a susceptible host
•Involves contact of the mucous membranes of the eyes, nose, or mouth of a host with large droplets (greater than 5 µm) that contain microorganisms
- Travel 3ft at most
How far do droplets travel
3 feet or less
Droplet contamination examples
➢Influenza
➢Meningitis
➢Diphtheria
➢Pertussis
➢Streptococcal pneumonia
Airborne Transmission
Occurs from dust that contains spores or by means of droplet nuclei
➢Droplet nuclei are particles of evaporated droplets containing microorganisms and measuring 5 microns (micrometers, µm, 0.001 mm) or smaller.
➢Can remain suspended in the air for long periods
Airborne examples
➢TB
➢Varicella viruses like chickenpox (also transmitted via direct contact)
Natural Resistance
Provided by mechanical barriers of intact skin and mucous membranes
-Skin
-Mucous membranes
-Body’s chemicals
-Inflammatory response
-Interferons
Acquired Immunity (long term)
Occurs when an individual develops antibodies to a particular organism as a result of either infection or immunization
-History with the disease
-Vaccines
-Build antibodies
Passive Immunity
Occurs following an injection of preformed antibodies to a particular infection
• Patients given antibodies and they “go to work” to prevent the disease
• Weaken over time
• Newborns have passive immunity from mom’s circulatory system and may continue with breastfeeding
• Short term because individual’s own body is not producing the antibodies
Emerging Diseases
➢New diseases appearing in the population
➢Existing diseases that are rapidly increasing in incidence or geographic range
➢Resurgent or recurrent old diseases caused by an old or mutated pathogen
What are the Infection-control departments of hospital responsible for keeping up-to-date emerging diseases?
➢CDC: recommendations, recommends hospitals or healthcare settings in ways to prevent spread of infection
➢WHO: studies, collects, and complies infection data all around the world
Disease emergence is precipitated by many factors:
➢Increased human exposure to vectors in nature
➢Population growth and migration to crowded cities
➢Rapid international travel and transportation of goods
➢Contact with new strains of dangerous pathogens
➢Pathogen mutation caused by overuse of antimicrobial agents
➢Breakdown in public health measures
➢Climate change
➢Bioterrorism
Healthcare-Associated Infections (HAI)
Those that occur more than 48 hours after patient admitted to the hospital
Which infections are multi-drug resistant?
➢MRSA
➢VRE
Clostridium difficile
a gastrointestinal infection that causes diarrhea.
•Caused by a Gram-positive bacillus
•Difficult to control because it cannot be eliminated by routine asepsis methods
•Patients on antibiotics most susceptible
Bloodborne Pathogens
•HIV
•AIDS
•Hepatitis
•Needle-stick injuries are most common cause of transmission from patients to healthcare workers
Tuberculosis
•A contagious, airborne lung disease caused by M. tuberculosis
•Most patients are homeless, recent immigrants, or immunocompromised.
•Pre-employment screening required for healthcare workers and after known exposure
Preventing Disease Transmission
•Historical Perspective
•Standard Precautions
•OSHA Bloodborne Pathogens Standard
•Medical Asepsis
•Handling and Disposal of Contaminated Items and Waste
•Isolation Technique
Historical Perspective
•Quarantines were used to contain infectious diseases.
➢Not allowed to leave the house and no one could enter until all members were well
Isolation no longer commonly used, but still a legal practice of the U.S. Public Health Service for diseases such as
➢Cholera
➢Diphtheria
➢Smallpox
➢TB
➢Plague
➢Yellow fever
➢SARS
Protective measures of the past: Universal precautions vs Body substance precautions
➢Universal Precautions—focused on barriers against bloodborne pathogens
➢Body Substance Precautions—expanded protection to all moist body secretions
Standard Precautions (Current infection-control system)
Designed to reduce risk of transmission of infections from unrecognized sources of bloodborne diseases and from other pathogens in healthcare institutions
•Includes transmission-based precautions for:
➢Airborne
➢Droplet
➢Contact
OSHA Bloodborne Pathogens Standard
Published in 1991
•Requires employers to
➢develop an exposure-control plan for the work site that describes employee protection measures.
➢include engineering and work-practice controls to ensure the use of personal protective clothing and equipment.
➢provide signs and labels to identify biohazard materials.
➢provide annual bloodborne pathogen training, hepatitis B vaccinations, and medical care in the event of occupational exposure.