Unit 2 B&B - Lecture Flashcards

1
Q

Sperm + ovum = ?

A

zygote

3/1/24

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2
Q

What is the first major stage in development?

A

zygote

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3
Q

Multiple Choice

Which of the following are in the correct order, according to human development?
* zygote; blastocyst; morula; embryo
* morula; embryo; zygote; blastocyst
* zygote; morula; blastocyst; embryo
* blastocyst; zygote; morula; embryo

A

zygote; morula; blastocyst; embryo

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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4
Q

Multiple Choice

When does a human have the most synapses?
* early embryonic development
* early childhood
* late in fetal development
* adolescence

A

early childhood

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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5
Q

Multiple Choice

What is the name of the developmental period in which a human has the most quantity of neurons?
* adulthood
* at birth
* late in life
* adolescence

A

at birth

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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6
Q

Multiple Choice

Hormones are typically released ——– allowing them to exert effects throughout the body.
* into the synapse
* into the circulatory system
* into the brain
* outside the body

A

into the circulatory system

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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7
Q

Multiple Choice

Which component is necessary for apoptosis?
* Death genes
* Methylation
* Neurogenesis markers
* Neurotrophic factors

A

death genes

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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8
Q

Multiple Choice

Undifferentiated —— cells, if gathered from embryonic tissue and transplanted into the brain, will differentiate and integrate properly.
* mesodermal
* apoptotic
* stem
* ventricular

A

stem

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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9
Q

Multiple Choice

——– regulates all hormone secretions and acts similar to a thermostat.
* negative feedback
* positive feedback
* action potentials
* endocrine gland shut down

A

negative feedback

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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10
Q

Multiple Choice

Which of the following statements is correct?
* pheromones definitely allow women to “sync up” menstrual cycles
* unlike most mammals, humans are not sensitive to hormones
* humans have a very sensitive vomeronasal organ
* there is mixed evidence regarding humans and pheromones

A

there is mixed evidence regarding humans and pheromones

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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11
Q

Multiple Choice

—— is an example of a major class of steroid hormones produced by the ——
* testes; testosterone
* estrogen; gonads
* progestin; ovary
* progestin; gonads

ASK PROF - Got this wrong on quiz

A

answered “estrogen;gonads” but got it wrong

progestin - isn’t this synthetic progesterone? meaning it wouldn’t be produced in the ovary or gonads. This rules out C and D.

testes - testes are not hormones. This rules out A.

NEED TO ASK - Office Hours

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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12
Q

Multiple Choice

Which of the following hormones is MOST responsible for the masculinization of the zebra finch song system?
* testosterone
* estrogen
* progesterone
* androstenedione

A

estrogen

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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13
Q

Multiple Choice

Preventing estrogen synthesis in a male zebra finch during development would likely:
* lead to larger brain areas associated with song
* cause no significant changes in the song system of the brain
* create a gynandromorph bird
* lead to smaller brain areas associated with song

A

cause no significant changes in the song system of the brain

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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14
Q

Multiple Choice

Alzheimer’s disease causes a gradually loss of ———, due to the death of basal forebrain neurons.
* acetylcholine.
* dopamine.
* serotonin.
* norepinephrine.

A

acetylcholine

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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15
Q

Multiple Choice

The process of apoptosis requires what?
* Methylation
* Neurogenesis markers
* Death genes
* Neurotrophic factors

A

death genes

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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16
Q

Multiple Choice

Reproduction that does NOT include the fusion of gametes or recombination of chromosomes is known as what?
* asexual reproduction
* infertile reproduction
* monecious reproduction
* ansiogametic reproduction

A

asexual reproduction

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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17
Q

Multiple Choice

———- is a biological variable, including aspects of genes, hormones, gametes, and anatomy.
* sex
* gender
* sexuality
* masculinity and femininity

A

sex

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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18
Q

Multiple Choice

Which of the following accurately describes an epigenetic process?
* fertilization of an egg by a sperm
* cell differentiation in interneurons, due to exposure to sonic hedgehog proteins in the spinal cord
* preferring spicy food, because you were raised eating it
* in-vitro fertilization

A

cell differentiation in interneurons, due to exposure to sonic hedgehog proteins in the spinal cord

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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19
Q

Multiple Choice

If Sheldon Cooper were to conduct an experiment on his roommate Leonard Hofstadter to enhance Leonard’s spatial memory, which of the following factors should Sheldon most likely manipulate?

  • The number of glial cells in Leonard’s brain
  • The size of Leonard’s neurons
  • The rate of neurogenesis in Leonard’s adult brain
  • The number of neurons Leonard had at birth
A

The rate of neurogenesis in Leonard’s adult brain

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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20
Q

Name the type of chemical communication.

oxytocin promotes the start of contractions in pregnant mammals

Hormone, allomone, pheromone, or synaptic?

A

hormone

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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21
Q

Name the type of chemical communication.

a cat releases a scent indicating it is in heat

Hormone, allomone, pheromone, or synaptic?

A

pheromone

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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22
Q

Name the type of chemical communication.

neurons in the frontal cortex release dopamine in response to eating chocolate cake

Hormone, allomone, pheromone, or synaptic?

A

synaptic

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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23
Q

Name the type of chemical communication.

trout emit a chemical to warn other trout of danger when spotting a predator

Hormone, allomone, pheromone, or synaptic?

A

pheromone

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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24
Q

Name the type of chemical communication.

a flower attracts a bee by emitting a sweet scent

Hormone, allomone, pheromone, or synaptic?

A

allomone

Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)

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25
# Name the type of chemical communication. the pituitary secretes FSH into the bloodstream, affecting the gonads | Hormone, allomone, pheromone, or synaptic?
hormone ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #1)
26
# Multiple Choice Nicotine and alcohol are examples of well known: * types of polydactyly * birth defectors * teratogens * endocrine disruptors
teratogens ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
27
# Multiple Choice Neurotrophins are an excitatory neurotransmitter. * This statement is correct. * Incorrect; neurotrophins are inhibitory neurotransmitters * Incorrect; neurotrophins are both inhibitory and excitatory neurotransmitters * Incorrect; neurotrophins are different from neurotransmitters
Incorrect; neurotrophins are different from neurotransmitters ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
28
# Multiple Choice These types of glands are hormone producing tissues. * endocrine * epigenetic * neural * gonadal
endocrine ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
29
# Multiple Choice Which would not be considered an extrinsic influence on cells? * Induction * Nutrition * Genes * Experience
genes ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
30
# Multiple Choice During development, an organism can be permanently changed by a teratogen if it occurs during the ---------- period. * plastic * developmental * flexible * sensitive
sensitive ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
31
# Multiple Choice Which of the following statements is correct regarding humans? * men produce testosterone; but not estrogen * women produce testosterone and estrogen * women produce estrogen, only when they are pregnant * men do not produce testosterone or estrogen
women produce testosterone and estrogen ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
32
# Multiple Choice The development of ocular dominance as a results of increased connections between commonly used cells is an example of what? * Hebbian synapses * apoptosis * synaptogenesis * Watsonian connections
Hebbian synapses ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
33
# Multiple Choice Cell fate is determined by factors including chemical environment and genetic activity. This is also known as * apoptosis * epigenetics * sexual differentiation * methylation
epigenetics ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
34
# Multiple Choice Treating a female zebra finch egg with estrogen would most likely lead to which effect? * the brain would fail to develop * the brain would look more like the average male brain * the brain would look hyper-feminine * the brain would look no different
the brain would look more like the average male brain ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
35
# Multiple Choice In early development, the cells that create neurons undergo mitosis in the ----------. * cerebral cortex * spinal cord * neural tube * brain stem
neural tube ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
36
# Multiple Choice Why is it incorrect to say that sex is a binary characteristic in humans? * there are more than 2 possible combinations of sex chromosomes * none of these answers are correct * because biology does not determine sex * there are only 2 possible combinations of sex chromosomes
there are more than 2 possible combinations of sex chromosomes ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
37
# Multiple Choice From the analogy discussed in class, a gene is like a ------, while a chromosome is can be compared to a --------- * bookshelf with many cookbooks; single cookbook * single recipe; bookshelf with many cookbooks * single cookbook, single recipe * single recipe; single cookbook
single recipe (gene); bookshelf with many cookbooks (chromosome) ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
38
# Multiple Choice A mutation in the SRY gene would likely disrupt what? * gamete formation * all of these answers are correct * gonadal development * sexual differntiation
all of these answers are correct ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
39
# Multiple Choice If Dr. Meredith Grey were to invent a device that could accelerate one stage of the nervous system development in a patient, which stage would most likely result in the patient developing new neural connections? * Neurogenesis, the mitotic division of nonneuronal cells to produce neurons * Cell migration, the massive movements of nerve cells or their precursors to establish distinct nerve cell populations * Neuronal cell death, the selective death of many nerve cells * Synaptogenesis, the establishment of synaptic connections as axons and dendrites grow
Synaptogenesis, the establishment of synaptic connections as axons and dendrites grow ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #3)
40
# Multiple Choice Which of the following is NOT a major division of the CNS visible in early development? * spinal cord * forebrain * none of these answers is correct * hindbrain
none of these answers is correct | On quiz, chose spinal cord but got it wrong ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
41
# Multiple Choice A drug that changes the amount of sonic hedgehog in the developing embryo would disrupt what? * cell differentiation * spinal cord development * All of these answers are correct * glial cell development
All of these answers are correct ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
42
# Multiple Choice Hormones are a critical part of which function? * all of these answers are correct * stress * circadian rhythms * hunger and digestion
all of these answers are correct ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
43
# Multiple Choice If a kitten's left eye is occluded during the --------- visual cells later show -------- responses when visual stimuli is presented to the left eye * sensitive; decreased * critical; decreased * sensitive; increased * critical; increased
sensitive; decreased ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
44
# Multiple Choice Fragile X syndrome is characterized by a chromosome that is prone to breaking due to what? * unstable DNA * methylated genes * reduced chromosomal count * increased methylation
unstable DNA ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
45
# Multiple Choice Which of the following statements is correct regarding humans? * men produce testosterone; but not estrogen * women produce testosterone and estrogen * men do not produce testosterone or estrogen * women produce estrogen, only when they are pregnant
women produce testosterone and estrogen ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
46
# Multiple Choice Which of the following statements is correct? * non-human animals are classified by gender, not sex * biological sex is determined by societal expectation * gender is determined by steroid hormones * gender is unique to humans
gender is unique to humans ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
47
# Multiple Choice Which of the following conclusions are consistent with the findings on zebra finch, as discussed in class? * only genetics drive sexual differentiation in the brain * both hormones and genetics drive sexual differentiation in the brain * neither hormones nor genetics drive sexual differentiation in the brain * only hormones drive sexual differentiation in the brain
both hormones and genetics drive sexual differentiation in the brain ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
48
# Multiple Choice Preventing estrogen synthesis in a male zebra finch during development would likely: * create a gynandromorph bird * lead to larger brain areas associated with song * cause no significant changes in the song system of the brain * lead to smaller brain areas associated with song
cause no significant changes in the song system of the brain ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
49
# Multiple Choice At present, the only way to identify Alzheimer's disease with confidence is through * postmortem examination. * genetic screening. * olfactory testing. * MRI.
postmortem examination ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
50
# Multiple Choice PGT can NOT be used to assess what? * chromosomal abnormalities * all of these answers are correct * gender * chromosomal sex
gender ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
51
# Multiple Choice If Dr. Bruce Banner (a.k.a., the Hulk) were to mutate due to an experiment gone wrong, causing his nervous system to develop abnormally, which of the following stages would most likely be affected? * The formation of the three distinct cell layers in the embryo * The development of the neural tube from the neural groove * The transition from the embryo to the fetus stage * The division of the single cell after fertilization
The development of the neural tube from the neural groove ## Footnote Nervous System Development Quiz (Unit 2 - Quiz 1 - Attempt #2)
52
According to class, the ultimate function of the brain is [blank1].
homeostasis ## Footnote In Class Homeostasis Learning Check
53
Eating a bunch of very salty chips would mostly likely result in --------.
osmotic thirst ## Footnote In Class Homeostasis Learning Check
54
Why is it a good idea to rehydrate with a slightly salty solution after a period of heavy sweating?
sweating causes the loss of bodily fluids AND electrolytes like sodium ## Footnote In Class Homeostasis Learning Check
55
Humans are an ------- species
endothermic ## Footnote In Class Homeostasis Learning Check
56
Most homeostatic systems work on a --------feedback system.
negative ## Footnote In Class Homeostasis Learning Check
57
# Name the stages Zygote > -------------- > --------------- > ---------------- > --------------- | (prenatal)
zygote > **morula** > **blastocyte** > **embryo** > **fetus** ## Footnote Lecture 3/1/2024: Development of the Nervous System
58
The ----------- embeds to the uterus.
blastocyte ## Footnote Lecture 3/1/2024: Development of the Nervous System
59
Two weeks post-conception, the "baby" is called an ------------.
embryo ## Footnote Lecture 3/1/2024: Development of the Nervous System
60
The "baby" is not called a fetus until ----------------- post-conception.
eight weeks ## Footnote Lecture 3/1/2024: Development of the Nervous System
61
What are the 3 layers of cells in a developing human embryo?
Ectoderm, mesoderm, endoderm ## Footnote Lecture 3/1/2024: Development of the Nervous System
62
The ectoderm cells will eventually make up --------- and ----------- tissue.
skin, neural tissue ## Footnote Lecture 3/1/2024: Development of the Nervous System
63
Cells in the ----------------- will become the skeleton and cardiac system. | layer of cells in embryo development
mesoderm ## Footnote Lecture 3/1/2024: Development of the Nervous System
64
Cells in the --------------- will become the digestion and respiratory systems. | layer of cells in embryo development
endoderm ## Footnote Lecture 3/1/2024: Development of the Nervous System
65
Dorsal surface tissue will become the --------------- system.
nervous ## Footnote Lecture 3/1/2024: Development of the Nervous System
66
-------------- of the --------------- leads to development of the neural plate.
thickening; ectoderm ## Footnote Lecture 3/1/2024: Development of the Nervous System
67
The first step of neural development we've studied in class is the ---------------- of the ----------------------, which is explains the beginning of cells organizing themselves into the nervous system.
induction; neural plate ## Footnote Lecture 3/1/2024: Development of the Nervous System
68
Everything happening during development is induced by -------------------------.
chemical signaling ## Footnote Lecture 3/1/2024: Development of the Nervous System
69
The thickening of the ectoderm leads to the development of the neural plate. The neural plate then starts to form the -------------------, which then closes to form the ------------------.
neural groove; neural tube | neural crest is the "peak" of the neural groove ## Footnote Lecture 3/1/2024: Development of the Nervous System
70
The neural tube is where we find the --------------------. The anterior portion of the neural tube will become the ----------.
spinal cord; brain ## Footnote Lecture 3/1/2024: Development of the Nervous System
71
The neural tube forms about ----------- days post-conception.
22 ## Footnote Lecture 3/1/2024: Development of the Nervous System
72
A(n) ------------------- called ---------------- occurs if the neural tube fails to close correctly.
neural tube defect; spina bifida ## Footnote Lecture 3/1/2024: Development of the Nervous System
73
When something goes wrong during development of the neural tube, it results in a(n) --------------------------.
Neural tube defect ## Footnote Lecture 3/1/2024: Development of the Nervous System
74
Neural tube defects can be caused by low ---------------- and/or exposure to --------------------.
maternal folic acid; teratogens ## Footnote Lecture 3/1/2024: Development of the Nervous System
75
Chemicals that can impact or disrupt development are ------------.
teratogens | examples are alcohol and nicotine ## Footnote Lecture 3/1/2024: Development of the Nervous System
76
Why is extra folic acid included in so many products?
Because low maternal folic acid is associated with an increased risk of neural tube defects ## Footnote Lecture 3/1/2024: Development of the Nervous System
77
The most common neural tube defect is -----------.
spina bifida ## Footnote Lecture 3/1/2024: Development of the Nervous System
78
-------------- occurs when the neural tube does not close at the top, preventing proper development of the skull. It generally results in more severe outcomes than other neural tube defects.
anencephaly ## Footnote Lecture 3/1/2024: Development of the Nervous System
79
When the neural tube fails to close properly along the spinal cord area, it results in -------------------. It can have effects varying in severity.
spina bifida ## Footnote Lecture 3/1/2024: Development of the Nervous System
80
# True/False: Spina bifida is usually correctible with surgery after birth.
True ## Footnote Lecture 3/1/2024: Development of the Nervous System
81
Why is it hard to pinpoint what causes a birth defect?
birth defects due to teratogen exposure can occur at any stage during development; many issues can cause the same impacts AND one issue can cause many impacts ## Footnote Lecture 3/1/2024: Development of the Nervous System
82
a disruption to the cardiac system during development
congenital heart defect | congenital = happening during prenatal development ## Footnote Lecture 3/1/2024: Development of the Nervous System
83
A type of birth defect that is caused by the neural tube closing improperly
Neural tube defect ## Footnote Lecture 3/1/2024: Development of the Nervous System
84
When facial muscle bones are forming, they may not fully come together. This is known as ------------.
Orofacial clefts ## Footnote Lecture 3/1/2024: Development of the Nervous System
85
A birth defect that causes development of additional fingers and toes.
polydactyly ## Footnote Lecture 3/1/2024: Development of the Nervous System
86
Name three categories of teratogens.
Chemicals; infections; environments (internal and external) ## Footnote Lecture 3/1/2024: Development of the Nervous System
87
Earlier teratogen exposure usually leads to -------------------- deficits.
more severe ## Footnote Lecture 3/1/2024: Development of the Nervous System
88
List the six phases of brain (or nervous system) development.
1. neurogenesis 2. cell migration 3. cell differentiation 4. synaptogenesis 5. cell death (apoptosis) 6. synapse rearrangement ## Footnote Lecture 3/1/2024: Development of the Nervous System
89
# Name the phase of nervous system development. the birth of new neural cells
neurogenesis ## Footnote Lecture 3/1/2024: Development of the Nervous System
90
# Name the phase of nervous system development. cells leave ventricular zone and head to different areas in the body where they will start developing the nervous system
cell migration ## Footnote Lecture 3/1/2024: Development of the Nervous System
91
# Name the phase of nervous system development. this stage is dependent on cell's location or timing
cell differentiation ## Footnote Lecture 3/1/2024: Development of the Nervous System
92
# Name the phase of nervous system development. after cells are created, they create connections between one another to pass messages through the nervous system
synaptogenesis (creation of synapses) ## Footnote Lecture 3/1/2024: Development of the Nervous System
93
# Name the phase of nervous system development. excess neurons unable to get necessary chemical for survival start to die off
cell death (or apoptosis) ## Footnote Lecture 3/1/2024: Development of the Nervous System
94
# Name the phase of nervous system development. weaker synaptic connections are eliminated while stronger connections are kept and strengthened
synapse rearrangement ## Footnote Lecture 3/1/2024: Development of the Nervous System
95
---------- is a period of intense cell proliferation.
neurogenesis ## Footnote Lecture 3/1/2024: Development of the Nervous System
96
What is cell proliferation and during which stage in neural development does it occur most?
generation of new cells; neurogenesis ## Footnote Lecture 3/1/2024: Development of the Nervous System
97
Where does neurogenesis occur?
in the ventricular zone of the neural tube | region of neural tube responsible for massive amounts of proliferation ## Footnote Lecture 3/1/2024: Development of the Nervous System
98
the rate of cell proliferation within the ventricular zone of the neural tube can be about -------------------- per min.
250,000 ## Footnote Lecture 3/1/2024: Development of the Nervous System
99
Neurogenesis leads to the creation of cells that are not specialized yet, called:
undifferentiated cells ## Footnote Lecture 3/1/2024: Development of the Nervous System
100
at the start of cell migration, the cells are -------------.
undifferentiated | differentiation occurs as cells migrate ## Footnote Lecture 3/1/2024: Development of the Nervous System
101
During the migration phase, cells are only a(n) -------------- and a(n).
soma; immature axon ## Footnote Lecture 3/1/2024: Development of the Nervous System
102
How do undifferentiated cells become differentiated?
through chemical signaling interactions, specifically location or timing ## Footnote Lecture 3/1/2024: Development of the Nervous System
103
The ectodermal tissue acquires its neural fate through chemical signaling. Another series of signaling interactions determine the type of neural cell, --------- or -----------.
**neurons** (including motor neurons and interneurons) and **glia** ## Footnote Lecture 3/1/2024: Development of the Nervous System
104
Cells can be exposed to differentiation either through ---------- or ----------.
timing; location ## Footnote Lecture 3/1/2024: Development of the Nervous System
105
The signaling protein ----------------, is an example of cell differentiation through location.
Sonic Hedgehog ## Footnote Lecture 3/1/2024: Development of the Nervous System
106
The signaling protein, Sonic Hedgehog (Shh), is important for ------------------- development.
spinal cord ## Footnote Lecture 3/1/2024: Development of the Nervous System
107
A cell that encounters high Shh will become ----------; medium Shh will become ----------; low Shh will become ------------.
glia; motor neuron; interneuron ## Footnote Lecture 3/1/2024: Development of the Nervous System
108
In the cerebral cortex, neurons migrate from the ventricular zone on ------------------- to become -----------------------.
radial glia; gray matter ## Footnote Lecture 3/1/2024: Development of the Nervous System
109
Radial glia act as ---------- for neurons in the development of the cerebral cortex.
scaffolding | old cells form lower levels, new cells climb past them to higher levels ## Footnote Lecture 3/1/2024: Development of the Nervous System
110
Why is the cerebral cortex organized into such well-defined layers?
because neurons use radial glia as scaffolding, so newer neurons climb past layers of older neurons to higher levels. ## Footnote Lecture 3/1/2024: Development of the Nervous System
111
The final position of the layers of cerebral cortex is correlated exactly to -----------------.
the birthdate this is helpful because if we see defects in formation of cortex, we can look at the time in development that these cells were formed and identify what may have happened at that point in development. ## Footnote Lecture 3/1/2024: Development of the Nervous System
112
in the cerebral cortex, cells that are leaving later migrate past the older neurons, creating --------------- layering.
inside-out ## Footnote Lecture 3/1/2024: Development of the Nervous System
113
phase of nervous system development when synapses are created
synaptogenesis ## Footnote Lecture 3/1/2024: Development of the Nervous System
114
After synapses are formed, how does communication happen between the two cells?
chemical signaling ## Footnote Lecture 3/1/2024: Development of the Nervous System
115
during synaptogenesis, synapses are vital for cell-to-cell communication as well as ----------------
cell survival ## Footnote Lecture 3/1/2024: Development of the Nervous System
116
the ----------------- of unfinished axons are searching the extracellular environment for connections to ------------- of other cells. The neighboring cells attract the cells' axon by ---------------------. The --------- transforms into ---------, which connects to the --------------- of the postsynaptic cell, forming a(n) -----------. During which phase of nervous system development does this occur?
growth cones; dendritic spines; emitting chemical signals growth cone transforms into the axon terminal; dendritic spines; synapse synaptogenesis ## Footnote Lecture 3/1/2024: Development of the Nervous System
117
--------------------- discovered that connections between cells do not determine how many axons form, they determine -----------------------------. This process is determined by --------------------. | 1 is a person, 2 is a verb, and 3 is a thing.
Rita Levi-Montalcini; how many survive; neurotrophins ## Footnote Lecture 3/1/2024: Development of the Nervous System
118
The neurotrophin discovered by Levi-Montalcini.
Nerve Growth Factor ## Footnote Lecture 3/1/2024: Development of the Nervous System
119
What does nerve growth factor (NGF) do?
NGF is a neurotrophin protein released by cells necessary for axon survival. It plays a role in the stage of nervous system development where neurons are overproduced and die if they don't make a connection. Only cells that get NGF will make connections with other cells and survive. ## Footnote Lecture 3/1/2024: Development of the Nervous System
120
Does a healthy adult nervous system contain more neurons?
No, we have all of the cells needed at birth ## Footnote Lecture 3/1/2024: Development of the Nervous System
121
Between ----% and ----% of neurons created will die after migration.
50; 75 ## Footnote Lecture 3/1/2024: Development of the Nervous System
122
What is another word for cell death?
apoptosis ## Footnote Lecture 3/1/2024: Development of the Nervous System
123
# T/F Cell death (apoptosis) is unnecessary and harmful, and ideally, it would not occur during development.
False; cell death is normal and necessary otherwise we would have many cells that take up energy but don't provide any function for us ## Footnote Lecture 3/1/2024: Development of the Nervous System
124
In case something goes wrong, we ------------ cells during development.
overproduce ## Footnote Lecture 3/1/2024: Development of the Nervous System
125
Only cells that successfully compete for chemicals make functional connections and survive. What is this called?
Neural Darwinism ## Footnote Lecture 3/1/2024: Development of the Nervous System
126
# T/F: A healthy adult CNS has many neurons without appropriate connections.
False; a healthy adult CNS has **very few** neurons without appropriate connections ## Footnote Lecture 3/1/2024: Development of the Nervous System
127
Neurotrophins are very important during development and also throughout the lifespan. What are three things that neurotrophins do?
- promote cell growth and survival - guide axons - stimulate synaptogenesis ## Footnote Lecture 3/1/2024: Development of the Nervous System
128
---------------- are a family of proteins essential for development of the vertebrate nervous system and help with cell survival during development.
Neurotrophins ## Footnote Lecture 3/1/2024: Development of the Nervous System
129
Name 4 neurotrophins.
- nerve growth factor (NGF) - brain-derived neurotrophic factor (BNDF) - neurotrophin 3 (NT3) - neurotrophin 4-5 (NT4/5) ## Footnote Lecture 3/1/2024: Development of the Nervous System
130
------------ are expressed only when a cell undergoes apoptosis (in the absence of ------------)
death genes; neurotrophins ## Footnote Lecture 3/1/2024: Development of the Nervous System
131
Explain the process of cell death (apoptosis).
A cell does not receive neurotrophins and is unable to create strong enough synaptic connections with other cells. Death genes are expressed. The cell shrinks and loses any physical connections with neighboring cells then blebs, and the nucleus collapses. Finally, the cell breaks down into apoptopic bodies and remaining debris is broken down by white blood cells. ## Footnote Lecture 3/1/2024: Development of the Nervous System
132
The process of synapse rearrangement is ----------------------------, meaning cells that are not used die off.
experience-dependent ## Footnote Lecture 3/1/2024: Development of the Nervous System
133
Synapse rearrangement allows for ------------- and -----------.
neural adaptation and recovery ## Footnote Lecture 3/1/2024: Development of the Nervous System
134
The process of losing weaker connections between cells is known as ---------------.
Pruning ## Footnote Lecture 3/1/2024: Development of the Nervous System
135
Within 3 years, a human goes from about ------------ synapses per cell to ------------ synapses per cell.
2500 to 15000 ## Footnote Lecture 3/1/2024: Development of the Nervous System
136
Adults have approximately --------- synapses per cell.
7000 ## Footnote Lecture 3/1/2024: Development of the Nervous System
137
What is the ultimate function of the brain?
homeostasis ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
138
What is homestasis?
any biological processes that keep body variables within a fixed range ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
139
List some homeostatic mechanisms.
body temp, levels of water, oxygen, glucose, calcium, protein or fat, etc. sun, air supply, survival without water or food ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
140
Homeostasis is controlled by -------- and ------- systems.
physiological; behavioral
141
Homeostasis includes any biological processes that keep body variables within a -----------.
fixed range
142
Who holds the record for longest amount of time without water? How did this happen and what was his record?
Andreas Mihavecz was forgotten about in a jail cell for 18 days. He did not have water, but was able to lick condensation off of the wall. ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
143
Who holds the record for longest amount of time without food? How did this happen and what was the record?
Angus Barbieri lived for 382 days without food. He was under dr. supervision and received some nutrients throughout but no significant calories. He went from 456 lbs to 180lbs and died in 1990. The food deprivation period did not seem to impact his lifespan. ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
144
What is the average amount of time a person can go without water?
about a week ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
145
What is the average amount of time a person can go without food?
estimated to be between 21 and 40 days, but there is a debate about how long a person can go without food ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
146
What are three ways in which a person can die by anorexia?
- myocardial infarction - organ failure - refeeding and sodium toxicity (if refeeding is not supervised, this can be dangerous because the body is pulling salt from different places and NA/K pumps are not working correctly) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
147
If a person with anorexia undergoes refeeding unsupervised, they are at risk of -------------------.
sodium toxicity ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
148
Humans can go without air for about ------------------.
3 minutes ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
149
What is static apnea?
a person has trained themselves to go without oxygen for an extended period of time ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
150
The record for air deprivation (for someone who has undergone static apnea training) is --------------.
24 minutes and 3 seconds ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
151
When a person hypersaturates their lungs with pure oxygen then holds their breath for an extended period of time, it is known as -------------------.
oxygen assist ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
152
How did a Russian cult contribute to our understanding of sunlight deprivation?
The cult lived in tunnels underground, so children had never been exposed to sunlight. They developed vitamin D deficiencies (rickets) and serotonin deficiencies. ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
153
When a person's bones soften due to proloned and extensive vitamin D deficiency, it is called --------.
Rickets ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
154
Who holds the record for longest amount of time without sleep? What was the record?
A high schooler named Randy Gardner stayed awake for 11 days (264 hrs). ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
155
After being deprived of sleep for ------ to ------ days, a person will typically have several cognitive and physiological impairments.
2-3 days ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
156
------- is the maintenance of a stable, balanced, internal environment
homeostasis ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
157
homeostasis is controlled by ------- and ------- systems.
physiological; behavioral ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
158
Changes in our internal environment can affect -----------, a psychological process that induces or sustains certain behavior.
Motivation ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
159
The longer we go without eating, the longer our internal environment undergoes physiological changes = the more ----------- we will be to partake in certain behaviors.
motivated ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
160
----------------- > change in motivation > -----------------
**physiological event** > change in motivation > **change in behavior** ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
161
---------- generate their own heat through internal processes.
Endotherms ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
162
---------- get most of their heat from the environment
Ectotherms ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
163
Ectothermic organisms lack the internal physiological mechanisms for ---------------------.
temperature regulation (they rely on the environment for regulating temperature) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
164
Amphibians, reptiles, and most fish are ------------.
Ectotherms ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
165
It is a misnomer to refer to ectotherms as ----------------. Why?
cold-blooded; because ectotherms will die if their body temperature drops below freezing ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
166
What happens if an ectotherm's body temperature drops below freezing?
ice crystals will form in their cells and blood, causing blood vessels to rupture and the animal to bleed to death ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
167
Some insects and fish have evolved mechanisms that have -------- component in circulatory system, allowing them to essentially freeze solid without decaying.
antifreeze ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
168
Ectotherm's body temperature matches --------------.
their external environment ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
169
insects and fish with "antifreeze" component have extraordinary ---------- ability
blood-clotting | can quickly repair ruptured blood vessels ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
170
Endoterms have internal physiological mecahnisms that ----------------------.
help maintain almost constant body temperature (small temperature range) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
171
Most mammals and birds are --------.
endothermic ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
172
What is a disadvantage of being endothermic?
it requires a lot of energy and fuel ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
173
We can decrease our body temperatures through physiological responses like --------- or ---------.
sweating; panting ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
174
We can increase our body temperatures through physiological responses such as ---------, ---------, ----------, etc.
shivering; decreasing blood flow to skin; fluffing out fur to increase insulation ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
175
What is the advantage of being endothermic?
Muscle activity benefits from being as warm as possible;  Ready for vigorous activity much more quickly than endotherms ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
176
Homeostatic mechanisms are primarily ------------------ systems.
negative feedback ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
177
What is the set point?
The optimal value that we want our homeostatic systems at (e.g., set point for temperature in humans is 98.6) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
178
A deviation from the set point results in --------------------.
a compensatory action (ex. if we get too cold, we'll shiver) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
179
A ----------- is a range of tolerance in a system.
set zone (ex. think of a thermostat) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
180
On a line graph, a negative feedback system would be represented by a --------- line.
wavy the value will reach its peak then the body will take action to lower it; the value will reach its low point, then the body will take action to raise it (ex. thermostat) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
181
In a negative feedback system, there will be ---------- above and below the --------- temperature.
variability; average ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
182
Physiological systems show --------------.
redundancy | they are monitored by more than 1 mechanism ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
183
What are the two thermoregulatory systems in rats?
- **autonomic:** reduces body heat produced and increases blood flow to tail (bc it is not covered in fur and dispenses a lot of heat) - **behavioral:** animals will seek out colder environment - - Preoptic area (POA) - Warm sensitive neurons ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
184
In rats, lesions to -------- impair physiological responses to cold. This only impacts --------------- regulation; not ------------ response.
POA; autonomic; behavioral ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
185
What are the three strategies used to regulate behavior in a thermoregulatory system?
1. change exposure of body surface (tuck in tail) 2. change external insulation (ex. wear coat) 3. change surroundings (go to warmer area) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
186
In rats, lesions to the POA **do not** impact ------------- responses to cold.
behavioral ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
187
Lesioning the ---------- in rats impacts autonomic regulation of temperature, whereas lesioning the --------------- impacts behavioral regulation of temperature
POA; lateral hypothalamus ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
188
Research into the POA and lateral hypothalamus's roles in rat's thermoregulation suggests what?
rats regulate their body temperature in at least two ways, and each is moderated by a different part of the brain ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
189
The ------------- is involved in reward, feeding, sleep, stress.
lateral hypothalamus ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
190
In rats, lesions to the -------------------- cause the rats to stop behavioral regulation of temperature. They do not involve ------------ responses.
lateral hypothalamus; physiological ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
191
--------- heavily rely on behavioral thermoregulation responses.
Ectotherms ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
192
What are two thermoregulation behaviors of ectotherms?
- moving toward or away from a heat source - allowing their temperature to rise to fight infection (endotherms use internal processes to generate a fever) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
193
Endotherms use -------------- processes to generate a fever to fight infection.
internal ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
194
Where are thermoreceptors found?
throughout the body in the skin; body core; and hypothalamus ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
195
What are TRP receptors?
temperature-sensitive receptors ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
196
We use --------------- to monitor our thermoregulatory system.
thermoreceptors/TRP receptors ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
197
Which receptors respond to capascin and menthol?
TRPV1 ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
198
What are TRP receptors responsible for?
detecting temperature and transmitting info ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
199
TRP receptor pathway
spinal cord > brainstem > hypothalamus ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
200
What happens when body temperature goes outside of set zone?
neural regions initiate physiological and behavioral responses to try to return temperature to the set zone (sweat, shiver, find different environment) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
201
# True/False: Our thermoregulatory system only monitors our external environment.
False; also regulates internal temp ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
202
What is the set zone for human body temperature?
about 95 to 107 degrees F ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
203
When internal core reaches ------- degrees Farenheit, initial symptoms of hypothermia set in, including shivering, dizziness, confusion, increased heart rate.
95 ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
204
The average "normal" body temperature for a human is -----------.
98.5 ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
205
Our temperature varies ------------.
throughout the day (lower in the AM and varies during sleep, activity) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
206
Women tend to have slightly -------- baseline temp than men
higher (by about .5) ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
207
generally normal optimal temperature range
97-99 degrees ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
208
--------- typically indicates an average fever resulting from illness or infection
101.5 degrees ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
209
-------- degrees is classifed as a serious fever.
103 ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
210
At --------- degrees, people can experience multiple organ failure and seizures.
107 ## Footnote LECTURE 3/18/2024: HOMEOSTASIS
211
What are some homeostatic systems?
Temperature, hunger, thirst ## Footnote LECTURE 3/20/2024: THIRST
212
What is an endotherm and how does it differ from an ectotherm?
WRONG FLASHCARD A set point is the “ideal” point (98.6degrees) A set zone – range that the system needs to stay in for survival
213
What is a set point and how dies it differ from a set zone?
WRONG FLASHCARD Body temp comes from organism vs. body temp comes from external environment
214
What are TRP receptors?
Thermoreceptors – receptors important for monitoring internal and external temperature; also play a role in pain, touch, gustatory/taste system
215
Excessive water loss is -------.
dehydration
216
Fluid retention is essential because we need it in the ------------------ and -------------------.
intracellular compartment; extracellular compartment
217
The extracellular compartment is divided between:
- interstitial fluid (extracellular fluid) - blood plasma (in cardiac system, carries hormones, etc.
218
When we move outside of the set zone for thirst, we become -------.
dehydration
219
why do we need water?
water moves through major components in the body and is needed for biological function; needed in both intracellular compartment and extracellular compartment
220
We want a -------------- in fluid and ions across both sides of cellular membrane.
balance
221
Body attempts to balance ---------- and --------- of fluid across both sides of the membrane.
volume (equalization pressure); concentration (chemical diffusion pressure)
222
Thirst is triggered due to internal changes in fluid ------------ or --------------.
volume (amount of fluid in body); concentration (ratio of fluid to sodium)
223
------------- monitor blood pressure and amount of fluid in the system.
Baroreceptors | need enough blood to keep everything moving through bloodstream
224
Baroreceptors are highly involved in the ------------ nervous system.
sympathetic
225
If baroreceptor system is disrupted, we get activation of the sympathetic nervous system. This causes -------------- and ----------------.
arteries to constrict; several hormonal systems to activate
226
Why do arteries constrict in dehydration?
causes blood pressure to increase; makes it so circulatory system does not need as much fluid to fill the entire system
227
Water in body needs to be within -------- range.
narrow
228
Concentration of chemicals in water is a -------------- step for all chemical reactions in the body.
rate-limiting
229
It is safer for humans to -------------- and ------------ than it is to risk having too little fluid.
overhydrate; release
230
A hormone released by the posterior pituitary moves through the circulatory system and helps monitor and maintain overhydration/release process
vasopressin
231
vasopressin can increase -------------- by constricting ------------ to compensate for low fluid volume.
blood pressure; blood vessels
232
vasopressin works with kidneys to:
reabsorb water and excrete highly concentrated urine
233
The less fluid in the body, the ------------ kidneys will absorb it before excreting.
more
234
What are the two different kinds of thirst?
osmotic thirst and hypovolemic thirst
235
-------- results from change in sodium concentration. How is it caused?
osmotic thirst; eating salty food or adding too much salt too system
236
---------------- results from overall loss of fluids. How does this happen?
hypovolemic thirst; blood loss, sweating, etc. there is no change in solute concentration (we sweat out both fluid and salt)
237
Osmotic thirst is triggerd by -----------------.
osmotic pressure
238
When increasing sodium adds ions in blood and intersitital fluid (higher sodium outside of cell); creates -----------
osmotic pressure
239
In osmotic pressure, there is a ------------ of solutes outside of cell.
higher concentration
240
Water losses without ------------------ result in osmotic thirst. What types of behaviors can cause osmotic thirst?
loss of sodium; respiration and urination (solute concentration increases and the net effect is that the the balance of concentration in system is changed)
241
242
How does the body detect osmotic pressure?
osmosensory neurons (monitor concentration of solute in blood -- detect osmotic pressure and sodium content of blood)
243
Where do we see osmosensory neurons in the brain?
OVLT (organum vasculosum laminae terminalis), subfornical organ, preoptic area)
244
Where do we find osmosensory neurons in the periphery?
stomach and digestive tract
245
Osmosensory neurons monitor the changes in ------------- of EC fluid.
concentration (also monitors osmotic pressure)
246
Osmosensory neurons relay information to --------------, which interacts with ----------- and --------------. These both play role in interactions with the endocrine gland, ------------------.
hypothalamus supraoptic nucleus paraventricular nucleus pituitary gland
247
What does the pituitary gland release when osmotic pressure is detected?
vasopressin
248
What structures control the rate at which vasopressin is released when osmotic pressure is detected?
supraoptic nucleus paraventricular nucleus
249
Vasopressin interacts with ---------- and -------------.
blood pressure; water absorption
250
------------ is associated with low volume of body fluids.
hypovolemic thirst
251
What does angiotensin II (AII) do?
increases blood pressure by constricting blood vessels (vasopressin can do this too)
252
What does aldosterone do?
stimulates kidneys to conserve sodium; aids in water retention
253
What happens in the kidneys during hypovolemic thirst?
aldosterone stimulates kidneys to conserve sodium and aide in water retention (limit dehydration through urination)
254
Other species use aldosterone to -----------------.
live in sea water (conserves water retention, prevents extreme dehydration)
255
How does aldosterone impact the brain?
stimulates thirst and drinking behavior (it is not enough to retain fluids; we also need to replace them)
256
Homeostatic systems --------- mechanisms, trigger ------------ response, trigger -------------- response, then leads to -------------- response.
monitor physiological (thirst) psychological (sensation of thirst) behavioral (seek out water)
257
Hypovolemic thirst creates preference for -------------- water. Why?
slightly salty because pure water will dilute body fluids and change osmotic pressure; if we have hypovolemic thirst, we want to replace both sodium and water so we don't trigger osmotic thirst
258
If hypovolemic thirst is treated with pure water and no salt, it results in ------------------------, which causes a strong craving for ------------------.
sodium-specific hunger; salty foods ## Footnote Lecture 3/20/2024: Thirst
259
Sodium-specific hunger develops automatically to restore -------------------------.
solute levels in the blood ## Footnote Lecture 3/20/2024: Thirst
260
Why does gatorade exist?
to address hypovolemic thirst -- since you lose both sodium and water when sweating, you need to replenish both ## Footnote Lecture 3/20/2024: Thirst
261
In thirst system: - Where are the receptors/how is the system monitored? - What are the pathways? - What physiological responses are triggered? - What behavioral responses are triggered?
## Footnote Lecture 3/20/2024: Thirst
262
In thirst system: Where are neurons that are monitoring osmotic pressure located/how is this information getting to the brain?
## Footnote Lecture 3/20/2024: Thirst
263
In thermoregulatory system: - Where are the receptors/how is the system monitored? - What are pathways to the brain? - What are physiological responses? - What are behavioral responses?
264
In hunger system: - Where are the receptors/how is the system monitored? - What are pathways to the brain? - What are physiological responses? - What are behavioral responses?
265
What is basal metabolism?
how much energy the body uses when it is just surviving (energy necessary to keep the body alive) ## Footnote Lecture 3/22/2024: Hunger & Satiety
266
Why won't dietary changes always produce changes in weight?
**basal metabolism means that our stores of energy are under homeostatic control** -- meaning we have long-term stores of energy that we're able to use, so if we experience a short-term energy intake or expenditure, we won't instantly see changes in body weight
267
--------- and ---------- are contrasting homeostatic mechanisms responsible for maintaining adequate nutrition in the body.
hunger; satiety
268
How does basal metabolism control energy usage?
* producing heat/keeping body at correct temperature * maintaining membrane potentials * other life-sustaining processes
269
Basal metabolism and energy use are under ----------- control.
homeostatic
270
Because basal metabolism and energy use are under homeostatic control, there is ------------- because they can be ------------.
variability; adjusted
271
When we talk about homeostatic regulation in hunger and satiety, we are talking about -------------------- and -------------------- regulation.
energy intake; nutrient
272
Why is nutrient homeostasis necessary?
Making sure we are taking in not just the right amount of energy/food, but also that that energy source/food has the proper nutrients
273
------------- are chemicals required for function, maintenance, and growth.
nutrients
274
Nutrient homeostasis involves regulation of ------- and ---------.
eating; body energy
275
Like other homeostatic mechanisms, basal metabolism and nutrient regulation involve ------------ mechanisms.
redundant
276
What is the principal sugar used for energy in the body?
Glucose | the brain, in particular, is incredibly glucose-hungry
277
Glucose is so important that (similar to water) we overconsume and store it short-term as ------------- in --------------- and ---------------.
glycogen; liver and muscles
278
process of storing glucose into glycogen is called ------------------, and it is monitored by the pancreatic hormone, ---------------.
glycogenesis; insulin
279
When body's circulating glucose levels drop too low, ----------- works to convert ---------------- into -------------.
glucagon converts glycogen into glucose; then glucose is available in bloodstream and can be used in tissues that need it
280
the process of making glucose available for use in the body; glucagon converts glycogen back into glucose
glycogenolysis
281
Insulin is important for both ----------------- and also for allowing -------------.
storing glucose; allowing circulating glucose to enter cells
282
Why does the body need insulin?
to help glucose transporters import glucose from the blood into most cells
283
----------- binds to unlock the --------------- channel to allow glucose to enter the cell.
insulin; glucose
284
In order to use circulating glucose (blood sugar) and to store glucose, we need -----------.
insulin
285
The ---------- and ------------- do not need insulin in order to use glucose.
brain; fatty acids
286
------- is needed for glucose storage and --------- is needed to release it.
insulin; glucagon
287
Some extra glycogen is stored as ------ for long-term storage.
fat
288
Insulin released is triggered by several mechanisms in ------ phases.
three
289
# Which phase of insulin release? Insulin release is mediated by brain in response to seeing, smelling or tasting food
cephalic phase
290
# Which phase of insulin release? insulin released when food enters digestive tract
digestive phase
291
# Which phase of insulin release? glucodetectors signal pancreas to release more insulin to help with glycogen storage
absorptive phase
292
Where are glucodetectors located?
liver
293
What are the two complementary processes of insulin release?
- reduce blood sugar - raise blood sugar
294
When glucodetectors recognize high levels of glucose, they signal the ---------- to release ----------. Insulin will remove excess ---------- from the blood in two ways: 1. allows insulin to --------------- 2. signals ---------- to . These two things ------------- blood sugar.
pancreas; insulin glucose; enter target tissues; liver; start storing glucose as glycogen lower
295
High blood sugar promotes ------------------ release.
insulin
296
When glucodetectors recognize low blood sugar, they signal the ------------ to release ------------, causing -------------- to break down into ------------, then enter into ------------------------------ and ------------ blood sugar level.
pancreas; glucagon; glycogen; glucose; circulatory system; raise
297
Low blood sugar promotes ------------- release.
glucagon
298
What happens when insulin is not working properly?
insulin fails to induce glucose absorption, resulting in diabetes
299
Diabetes is a failure of ----------- to induce ----------- absorption.
insulin; glucose
300
What does diabetes (a failure of insulin to induce glucose absorption) lead to?
- chronic high blood sugar - damage to cells depending on glucose
301
Which cells can diabetes impact?
those that are glucose dependent, including: - eye disease - renal failure - diabetic foot - stroke - heart damage - nerve disease - arteriosclerosis
302
People with diabetes are ---- times more likely to have an amputation due to nerve damage.
20
303
a loss of sensation due to nerve damage
sensory neuropathy
304
When we talk about hunger, we're talking about the brain monitoring -------- and -------- levels along with other info to monitor ------------.
glucose; insulin; appetite
305
# True/False Neither insulin nor glucose alone is an appetite signal.
True
306
Areas associated with the --------------, including the ----------------------- and ----------------------, are especially important in controlling hunger.
hypothalamus; ventromedial hypothalamus (VMN); lateral hypothalamus (LH)
307
According to a study, VMH lesions caused -------------. This change happened due to ---------------. Thus, researchers believed this to be a ------------ center.
obesity; significant increase in food intake; satiety
308
According to a study, LH lesions caused -------------. This change happened due to ---------------. Thus, researchers believed this to be a ------------ center.
weight loss; refusal to eat; hunger
309
In the study lesioning VMH and LH areas, the weight of both lesioned groups stabilized over time. What did this indicate about these brain areas?
since both kinds of lesioned animals experienced satiety and hunger, neither center is wholly responsible for either sensation amount of food affecting fullness/satiety changed depending on where lesion was
310
In addition to brain areas, many ----------- are important in regulating hunger and satiety.
hormones
311
Hormones drive -------------------- appetite control.
hypothalamic
312
There is a circuit within ----------- that integrates various hunger and satiety hormones.
arcuate nucleus
313
-------------- and ----------- constantly release hormonal signals about ------------, short-term and long-term energy balance in the body.
digestive organs; fat tissues; ongoing
314
Leptin is released by -------------- and gives info about ------------ energy.
fat cells; long-term
315
Initially it was thought that leptin deficiency was responsible for --------. This was found to be true in mice but there was not a strong correlation in humans.
obesity
316
Ghrelin is synthesized and released by --------------.
the stomach
317
Ghrelin is high ------------ we eat. It --------------------------.
before; drops off after eating
318
Which hormone works as an appetite stimulant?
ghrelin
319
PYY3-36 is released by ---------------.
intestinal cells
320
We have ------- levels of PYY3-36 before eating and -------- levels after eating. It works as an ----------------------.
low; high; appetite suppressant
321
---------- feeding, cholecystokinin (CCK) is released by the ---------.
After; gut
322
CKK acts on the -------- nerve to ------------ appetite.
vagus; inhibit
323
Semiglutides like ---------- or ----------- are -------------- peptide (GLP-1) agonists.
Wegovy; Ozempic Glucagon-like
324
What are the effects of semiglutides?
- slow gastric emptying (keep food in stomach and digestive tract for longer; increases fullness; changes rate of hormones) - increase insulin secretion - reduces insulin resistance - increases cellular energy consumption - increases satiety signals - reduces appetite signaling (reducing overall food intake) - works with liver to reduce stored energy
325
Although people using semiglutides lost weight, they ------------ after stopping the drug, suggesting treatment may need to be -------------- for it to be effective.
regained the weight; ongoing | main reason its effectiveness is controversial
326
# True/False: Bacteria do a lot more than cause infection.
True
327
Why might we need a paradigm shift to how we think about bacteria?
bacteria do much more in our body than cause infections; many "good" bacteria
328
A healthy adult human has about ----------------- bacteria just in the gut.
100 trillion
329
# True/False: Humans are more bacteria than they are human.
True
330
The communal gut microbial genome (microbiome) is about ------- times larger than the human genome.
150
331
We may think about the microbiome as its own -----------.
organ | all of our bacteria weighs about 1kg
332
The microbiome is an ------------------ of cells with no --------------------. Compare to ------------- system?
organized system of cells; no distinct structure; immune
333
Our ------------- change our gut microbiome, so it is incredibly -----------.
experiences; individualized
334
Host and microbiome have -------------- interests and interplay. Neither wishes the other -----------.
evolutionarily-aligned; harm
335
As result of evolution, we have lost some genes and bacteria have maintained some genes that ----------------.
are only beneficial to the host
336
The ---------------- provides critical biosynthetic pathways that significantly extend host metabolic and physiologic capacity (exend our health as well as
microbiome
337
What is a commensal relationship?
Our bacteria keep us alive (by extending out metabolic and physiologic capacity) and by staying alive, we continue to provide a host for bacteria
338
We have bacteria in our gut that express -------------- which converts glycans into useable sugars. No ---------------- is capable of digesting glycans--only bacterial enzymes.
glycoside hydrolase; no human enzyme
339
Many of the ----------- that we eat are only digestible by bacteria, and bacteria produce these short-chain fatty acids.
carbohydrates
340
---- to -----% of adult energy may be generated by ---------- production or stored as fat.
10-15%; short-chain fatty acid ## Footnote Lecture 3/22/24: Hunger & Satiety
341
The POA and LH are both involved in ----- and this is an example of ------ in homeostatic mechanisms. * body temp regulation; redundancy * body temp regulation; isolation * appetite regulation; redundancy * appetite regulation; isolation
body temp regulation; redundancy ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
342
In humans, a body temperature below ------ degrees F or above ------ degrees F is generally considered cause for significant concern.
95; 106 ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
343
The ----- controls blood pressure in part as a response to activation of -------. * sympathetic nervous system; baroreceptors * sympathetic nervous system; thermoreceptors * parasympathetic nervous system; baroreceptors * parasympathetic nervous system; thermoreceptors
sympathetic nervous system; baroreceptors ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
344
Baroreceptors are found in the organs of the ------.
sympathetic nervous system (got this wrong on quiz, should double-check) | answered "peripheral" but wrong on quiz ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
345
Damage to the lateral hypothalamus would disrupt which of the following in rats? * all of these answers are correct * sleep behaviors * feeding behavior, leading to weight loss * autonomic thermoregulation
all of these answers are correct ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
346
The intestinal hormones, ----- and -------, both show a rapid increase in secretion in response to eating, and have the effect of appetite suppression. * PYY3-36; GLP-1 * ghrelin; leptin * PYY3-36; ghrelin * GLP-1; leptin
PYY3-36; GLP-1 ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
347
Disrupting -------- production would interfere with the changing of glucose to glycogen. * Aldosterone * CCK * Glucagon * Insulin
Insulin ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
348
Anticipation of glucose triggers the ------ phase of insulin release. * Cephalic * Digestive * Absorptive * Somatic
Cephalic ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
349
Which pairing is correct? * none of these answers are correct * osmotic thirst; cardiac baroreceptors * hypovolemic thirst; OVLT * hypovolemic thirst; amygdala
none of these answers are correct ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
350
Why does eating more slowly make you feel fuller? * increased cholecystokinin production * decreased cholecystokinin production * increased vasopressin production * decreased vasopressin production
increased cholecystokinin production ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
351
When food hits your stomach, receptors detect which of the following sensations which contribute to satiety? * stretching * fullness * flavor of food * leptin release
stretching ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
352
A child born via cesarean section would likely have ------- bacteria in their gut microbiome than a child born via vaginal delivery. * different * more * less * the same
different ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
353
Adult humans get an estimated 10-15% of their daily energy from what? * bacteria in the gut microbiome producing SCFAs * fat cells converting glycogen into insulin * leptin converting glucose into glycogen * potatoes
bacteria in the gut microbiome producing SCFAs ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
354
A patient with bulimia nervosa would typically have which of the following symptoms? * cycles of binge-purge behaviors * little to no appetite * extremely low body weight * all of these answers are correct
cycles of binge-purge behaviors ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
355
As a mammal, Snoopy can maintain high and relatively constant body temperatures, allowing him to play with Woodstock and keep cool by sweating on a hot day. Snoopy would be an example of an -------- * Endotherm * Ectotherm * Ectoplasm * Endoplasm
endotherm ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
356
----------- allows for the separation of intracellular and extracellular fluids, facilitating specialized functions within cells while maintaining overall fluid balance. * Compartmentalization * Osmosis * Diffusion * Fluid pressure
compartmentalization ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
357
The minimum caloric intake required by Patrick Mahomes to sustain his basic bodily functions when he's not playing football is determined by which bodily process? * Basal metabolism * Diffusion * Homeostasis * Thermoregulation
Basal metabolism ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
358
Sarah has Crohn's disease, which affects her appetite. Her doctor in Michigan is able to give her a prescription for ----------, as there's some evidence that this drug may help her gain some weight and have a better appetite. * Cannabis * Oxycodone * Steroids * SSRIs
cannabis ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
359
# physiological, behavioral, both, or neither? A salamander lying on a sunny rock
behavioral ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
360
# physiological, behavioral, both, or neither? An elephant using its trunk to spray water on its body
behavioral ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
361
# physiological, behavioral, both, or neither? Complaining about the weather in Nebraska
neither ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
362
# physiological, behavioral, both, or neither? Damage to the POA disrupts ___ responses
physiological ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #1
363
Which of the following is NOT an example of a homeostatic process? * none of these answers are correct * body temperature regulation * hydration/ thirst * respiration/ breathing
none of these answers are correct ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
364
The body uses a combination of ------ signals to detect changes in the body and --------- signals to respond to those changes. * afferent; efferent * efferent; afferent * heterostatic; homeostatic * homeostatic; heterostatic
afferent; efferent ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
365
These types of neurons monitor the concentration of the extracellular fluid. * osmosensory * osmotic * allostatic * sensory
osmosensory ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
366
Gut neurons communicate information about the regulation of saltiness of fluid within the stomach and intestine via the -----------. * vagus nerve * subfornical organ * prefrontal cortex * organum vasculosum
vagus nerve ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
367
Having an extremely low body fat would potentially disrupt the body's ability to do what? * store energy for long term use * convert glucose to glycogen * use glucose * maintain hydration
store energy for long term use ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
368
Which of the following hormones are produced in the gut? * all of these answers are correct * PYY * CCK * ghrelin
all of these answers are correct ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
369
------- is converted into ------ for storage as a reserve fuel. * glucose, glycogen * glycogen, glucose * glucose, glucagon * glucose, lipids
glucose, glycogen ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
370
Which of the following statements is correct about healthy adult humans? * they have more bacterial cells than glia * they have more neurons than glial cells * the human body contains 150x more genes than the gut microbiome * the gut microbiome makes up about 10% of their body weight
they have more bacterial cells than glia ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
371
Which of the following statements is correct? * bariatrics is the study of the causes, prevention, and treatment of obesity * obesity has reached epidemic proportions in the Europe, but not the US * the majority of US adults do not meet the diagnostic criteria for obesity * all of these answers are correct
bariatrics is the study of the causes, prevention, and treatment of obesity ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
372
--------- maintains a stable internal environment by responding to immediate physiological needs, while ----------- anticipates and adjusts to potential challenges or stressors. * Homeostasis, allostasis * Allostasis, homeostasis * Homeostasis, anxiety
homeostasis; allostasis ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
373
You're at the LNK Airport on your way to a vacation in Chicago. As you approach the security checkpoint, you encounter various security measures, such as metal detectors and baggage checks. These security measures selectively allow certain individuals to pass through while restricting others. Similarly, a ----------- selectively allows certain molecules or ions to pass through while blocking others based on their size, charge, or solubility. * semipermeable membrane * permeable membrane * partial membrane
semipermeable membrane ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
374
Which organ in Claire Dane's body releases insulin when her blood glucose levels are too high, and glucagon when her blood glucose levels are too low? * Pancreas * Liver * Kidneys * Gallbladder
Pancreas ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
375
Which of the following hormones is NOT involved in appetite regulation? * Cortisol * Ghrelin * PYY * GLP-1
Cortisol ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
376
As a general rule, brain damage can occur in as few as ------- without oxygen. * 3 minutes * 24 minutes * 5 minutes * 4 seconds
3 minutes ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
377
Most homeostatic systems: * have multiple or redundant monitoring mechanisms throughout the body * rely on receptors in the CNS to monitor body systems * work by increasing enzyme activity in the synapse * rely on a positive feedback process
have multiople or redundant monitoring mechanisms throughout the body ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
378
If there is a high amount of sodium in the extracellular space: * fluid will be pulled out of the cells * fluid will be pushed into the cell * fluid will remain stable * sodium will be pushed into the cell
fluid will be pulled out of the cells ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
379
The ---- controls blood pressure in part as a response to activation of ------- * sympathetic nervous system; baroreceptors * sympathetic nervous system; thermoreceptors * parasympathetic nervous system; baroreceptors * parasympathetic nervous system; thermoreceptors
sympathetic nervous system, baroreceptors ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
380
Damage to the lateral hypothalamus would disrupt which of the following in rats? * all of these answers are correct * sleep behaviors * feeding behavior, leading to weight loss * autonomic thermoregulation
all of these answers are correct ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
381
Angiotensin II aids in sodium conservation by triggering the release of ------ * aldosterone * glycogen * glucose * angiotensin I
aldosterone ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
382
-------- amino acids can't be manufactured by the human body. * pancreatic * inorganic * dietary * essential
essential ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
383
Which pairing is correct? * hypovolemic thirst; subfornical region * all of these answers are correct * osmotic thirst; preoptic area * osmotic thirst; OVLT
all of these answers are correct ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
384
------- detect any increases in glucose and signal to the --------- to release more insulin. * glucodetectors, pancreas * glucodetectors, liver * insulin, pancreas * vagus nerve, pancreas
glucodetectors, pancreas ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
385
Which of the following is an example of a commensal relationship? * bacteria in the microbiome breaking down carbohydrates * bacteria in the digestive tract causing IBS * hormones in the stomach sending signals to the brain * changes in eating behavior after VMH orLH lesions
bacteria in the microbiome breaking down carbohydrates ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
386
Which of the following may occur as a symptom of anorexia nervousa? * severe food deprivation * all of these answers are correct * abnormal physiological hunger cues * typical dopamine signalling
severe food deprivation ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
387
--------- maintains a stable internal environment by responding to immediate physiological needs, while -------- anticipates and adjusts to potential challenges or stressors. * Homeostasis, allostasis * Allostasis, homeostasis * Homeostasis, anxiety
homeostasis, allostasis ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
388
-------- allows for the separation of intracellular and extracellular fluids, facilitating specialized functions within cells while maintaining overall fluid balance. * Compartmentalization * Osmosis * Diffusion * Fluid pressure
compartmentalization ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
389
-------- is energy stored for later use in the liver and skeletal muscles while --------- is used as rapid source of energy during periods of fasting or intense physical activity. * Glycogen, glucose * Glucose, glycogen * Glycogen, glycosis * Glucose, glycosis
glycogen, glucose ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #2
390
# physiological, behavioral, both, or neither? A kid getting "goosebumps" in a cold classroom
physiological ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
391
# physiological, behavioral, both, or neither? Putting on more clothing when chilly
behavioral ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
392
# physiological, behavioral, both, or neither? A mouse increasing blood flow to its tail
physiological ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
393
# physiological, behavioral, both, or neither? Damaging the LH disrupts ------- responses
behavioral ## Footnote Unit 2 Quiz 2: Homeostatis - Attempt #3
394
your brain's most important job (besides learning neuroscience)
Homeostasis ## Footnote Crossword
395
glucagon converts glucose into -- for storage
glycogen ## Footnote Crossword
396
sleep- ----- insomnia is characterized by difficulty falling asleep
onset ## Footnote Crossword
397
biochemicals that move through bloodstream to affect diverse targets
hormone ## Footnote Crossword
398
this "organ" suggests we are more bacteria than human
microbiome ## Footnote Crossword
399
receptor in the heart that monitors blood pressure, blood volume
baroreceptor ## Footnote Crossword
400
chemical signal used to communicate with others of your species, probably not used in humans (so we invented axe body spray spray instead)
pheromone ## Footnote crossword
401
steroid hormone found in males and females
testosterone ## Footnote crossword
402
eating too many Doritos might cause these neurons to make you thirsty
osmosensory ## Footnote crossword
403
outer ear structure, collects and directs sound waves
pinna ## Footnote crossword
404
primary energy source for body, sugar
glucose ## Footnote crossword
405
brain area generally dormant while you sleep
locus coruleus ## Footnote crossword
406
407
family of proteins that support developing cells, and help direct development
neurotrophins ## Footnote crossword
408
sensation of body movement and position
proprioception ## Footnote Crossword
409
booze disrupts this sleep stage, especially in the first few hours of sleep
REM ## Footnote crossword
410
interaction between environment and genes
epigenetics ## Footnote crossword
411
layer of the neural plate that becomes the CNS
ectoderm | NOTE: in crossword, it only accepts "endoderm" -- prof said its ecto ## Footnote crossword
412
band of axons that connects left and right hemispheres
corpus callosum ## Footnote crossword
413
basic taste associated with savory/meaty foods
umami ## Footnote crossword
414
------ tendon organs, receptor that detects muscle contraction
golgi ## Footnote crossword
415
legion this brain area to make fatter rat | answer is abbreviated
VMH ## Footnote crossword
416
the primary biological "clock" | abbreviated
SCN ## Footnote crossword
417
process theory of color perception based on opposite response to different wavelengths of light
opponent ## Footnote crossword
418
left hemisphere controls right side of the body, ---------- representation
contralateral ## Footnote crossword
419
bad dream causing waking from stage 3/SWS
night terror ## Footnote crossword
420
non-receptor cell type found in the retina, axons make the optic nerve
ganglion ## Footnote crossword
421
gene on the Y chromosome in humans, usually results in formation of testes | abbreviated
SRY ## Footnote crossword
422
the early, permanent effects of hormones on development
organizational ## Footnote crossword
423
normal and necessary death of cells, like those that don't form connections during development
apoptosis ## Footnote crossword
424
hormone released by adipose fat cells, indicate long-term energy stores
leptin ## Footnote crossword
425
an example may include an alarm clock, the sunrise, or lunch time | hint: think about the entrainment process
zeitgeber ## Footnote crossword
426
olfaction, unlike most senses, bypasses this "sensory relay" point in the brain
thalamus ## Footnote crossword
427
cranial nerve with an important role in hunger and satiety
vagus ## Footnote crossword
428
neural tube defect associated with low folic acid, alcohol, or nicotine exposure
spina bifida ## Footnote crossword
429
most sleeping pills target receptors for this neurotransmitter, acting as agonists
GABA ## Footnote crossword
430
What would be the effect of a drug that BLOCKS the production of Per proteins in the SCN? * glutamate signalling would be blocked * the SCN would not produce melatonin * the SCN would not entrain to light * the pineal gland would not produce histamine
the SCN would not entrain to light ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
431
---- waves are typically observed in participants who feel relaxed and keep their eyes closed. * delta. * alpha. * beta. * gamma.
alpha ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
432
In the typical sleep pattern of healthy adults, the first REM period of the night may last a few minutes while the last REM period is likely to: * last much longer * last the same amount of time * last much less time * REM does not occur later in the night
last much longer ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
433
According to research on circadian rhythms and performance, which football team would have an advantage in a game played in Los Angeles, CA that began at 6pm local time (9 PM EST)? * neither team would have an advantage * any team, as long as they were playing against the Packers * a team from the west coast * a team from the east coast
a team from the west coast ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
434
The neurons that allow us to move from one stage of sleep to another are found in the ____. * pons * cortex * hypothalamus * thalamus
hypothalamus ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
435
Tanya Tucker wakes up from a nap feeling groggy, nauseous and disoriented. What stage of sleep was she likely in just before she awoke? * REM * SWS * stage 2 * stage 1
SWS ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
436
Which experimental condition led to improved recall? * odor during learning and during REM sleep * odor during learning only * odor during learning and during SWS * odor during SWS only
odor during SWS only ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
437
Which of the following is NOT part of SCN cell activity? * clock and cycle form a dimer * glutamate "syncs" the activity to light exposure * the cycle repeats approximately every 24 hours * clock and cycle inhibit the activity of cry and per
clock and cycle inhibit the activity of cry and per ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
438
Oprah Winfrey buys an app that promises to help her learn a new language if she plays the lessons at night, while she sleeps. What type of learning is this? * REM state dependent learning * this is not an effective way to learn new information * learning via osmosis * SWS memory consolidation
this is not an effective way to learn new information ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
439
Which of the following is NOT a scientific theory used to explain the phenomenon of dreaming, as discussed in class? * dreams are a chance to review learned material from the day * we don't actually dream during sleep- we interpret our brain activity after we wake up * dreams help us to process emotions * dreams allow us to see patterns in our lives and make predictions about future behaviors
dreams allow us to see patterns in our lives and make predictions about future behaviors ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
440
LSD seems to cause dreamlike experiences due to activation of which receptor? * levodopa * 5HT 2D * 5HT 2a receptor * all serotonin sub receptors families
5HT 2A receptor ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
441
Leslie Knope has a disorder where she engages in organized behavior including running and eating (essentially acting out her dreams). She would likely be diagnosed with what? * REM behavior disorder * sleep apnea * night terrors * somnambulism
REM Behavior Disorder ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
442
In the world of Harry Potter, werewolves transform during a full moon due to a change in their biological rhythms. This is an example of which type of biological rhythm? * Circadian rhythm * Infradian rhythm * Tidal rhythm * Ultradian rhythm
Infradian ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
443
In the movie "Inception," characters enter a dream within a dream. Which stage of sleep is characterized by vivid dreaming and is similar to the dream state in "Inception"? * Stage 1 sleep * REM sleep * Stage 3 sleep * Stage 2 sleep
REM sleep ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
444
Tim stayed up late studying the night before his PSYC 350 exam and only got 4 hours of sleep. His friend Eric studied for a couple of hours after dinner and slept for 8 hours. Tim performed worse on his exam than Eric, showing that the key function of ---------- might not happen when we are sleep deprived. * Physical restoration * Memory consolidation * Niche adaptation * Conservation of energy
memory consolidation ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
445
Jocelyn has been waking up gasping for air and her partner has been complaining about her loud snoring. She brought this up with her doctor, who recommended she go to a specialist for a sleep study for a possible diagnosis of --------. * Sleep apnea * COPD * Insomnia * Sleep paralysis
sleep apnea ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
446
Imagine The Hulk experiences a sudden loss of muscle tone and collapses without losing consciousness when he gets angry. What condition could he be suffering from? * REM behavior disorder * Cataplexy * Somnambulism * Sleep paralysis
cataplexy ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
447
# Match the neurochemical action with its effect. increased acetylcholine
## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
448
# Match the neurochemical action with its effect. increased GABA
## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
449
# Match the neurochemical action with its effect. increased adenosine
## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
450
# Match the neurochemical action with its effect. inhibit GABA
## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 1
451
Which of the following statements about human sleep and wakefulness is NOT correct? * exposure to light early in the day improves sleep and wakefulness * humans have a slightly longer than 24 hour circadian cycle * adequate sleep helps people feel more awake during the day * after extreme sleep deprivation we must "make up" at least 50% of the missed sleep
after extreme sleep deprivation, we must "make up" at least 50% of the missed sleep ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
452
Based on previous experiments, if we removed all zeitgebers for an animal and examine its behavior, what results would we expect to obtain? * a change in the amount of activity * a change in the type of activity * a change in pattern of activity * all of these answers are correct
a change in the pattern of activity ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
453
What study provided evidence that cells of the SCN are a key "biological clock" in the brain? * performance studies in football players * lesion studies in cats * jet lag studies in dogs * SCN transplants in hamsters
SCN transplants in hamsters ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
454
Nearly all animal species are: * biphasic sleepers * either diurnal or nocturnal * crepuscular * most active during the day
either diurnal or nocturnal ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
455
Apply electrical stimulation to the ------ would wake up a sleeping individual and increase alertness in someone who is already awake. * reticular formation * SCN * hypothalamus * cortex
reticular formation ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
456
The bizarre nature of dreams (strange movement of time, odd events, etc) is likely due to ------ activity in the ----. * higher; amygdala * lower; temporal lobe * lowered; inferior frontal cortex * higher; insula
lowered; inferior frontal cortex ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
457
Which of the following is NOT part of SCN cell activity? * cry and per inhibit the activity of clock and cycle * clock and cycle cause cry and per to breakdown * DNA in the cells produce cry and per * clock and cycle form a dimer
clock and cycle cause cry and per to break down ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
458
Just as Nicole Kidman is falling asleep she experiences a hypnic jerk and wakes up. Why does this happen? * she has somnambulism * none of these answers is correct * her SCN is misfiring * her circadian rhythms are phase-shifting
none of these answers is correct ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
459
One theory on why we sleep is that: * humans evolved sleep to increase social connectivity among families * sleep is a time when the brain undergoes "cleaning" to remove cellular waste products * it is a false state; the brain is never fully asleep * none of these answers is correct
sleep is a time when the brain undergoes "cleaning" to remove cellular waste products ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
460
As discussed in class, levodopa treatment would likely lead to which effect? * all of these answers are correct * more vivid dreams * increased sleep latency (time to fall asleep) * decreased dopamine activity
more vivid dreams ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
461
One of the reasons that daylight saving time switches are hard on people is that it requires use to adapt to a slightly new schedule, or ------- our circadian rhythms. * phase shift * zeitgeber * de-entrain * free run
phase shift ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
462
In the world of Harry Potter, werewolves transform during a full moon due to a change in their biological rhythms. This is an example of which type of biological rhythm? * Circadian rhythm * Infradian rhythm * Ultradian rhythm * Tidal rhythm
Infradian rhythm ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
463
In the movie "Inception," characters enter a dream within a dream. Which stage of sleep is characterized by vivid dreaming and is similar to the dream state in "Inception"? * Stage 2 sleep * REM sleep * Stage 1 sleep * Stage 3 sleep
REM sleep ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
464
Like the diligent 'Hogwarts Express" transporting wizards from their daily lives to the wizarding world, which neural system faithfully transports our brains from the wakeful world to the land of deep, slow-wave sleep (SWS)? * The Pontine System * The Reticular Formation * The Hypothalamic Harmony Ensemble * The Basal Forebrain
the Basal Forebrain ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
465
Jocelyn has been waking up gasping for air and her partner has been complaining about her loud snoring. She brought this up with her doctor, who recommended she go to a specialist for a sleep study for a possible diagnosis of ----------. * Sleep paralysis * Insomnia * Sleep apnea * COPD
Sleep apnea ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
466
Considering the sleep adventures of Alice in Wonderland, if Alice were to walk and talk in her sleep, during which sleep stage would this most likely occur? * Stage 2 sleep * Slow-wave sleep (SWS) * REM sleep * Stage 1 sleep
Slow-wave sleep (SWS) ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 2
467
Which of the following statements about human sleep and wakefulness is NOT correct? * humans have a slightly longer than 24 hour circadian cycle * exposure to light early in the day improves sleep and wakefulness * after extreme sleep deprivation we must "make up" at least 50% of the missed sleep * adequate sleep helps people feel more awake during the day
after extreme sleep deprivation, we must "make up" at least 50% of the missed sleep ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
468
What would be the effect of a drug that BLOCKS the production of Per proteins in the SCN? * the pineal gland would not produce histamine * glutamate signalling would be blocked * the SCN would not entrain to light * the SCN would not produce melatonin
the SCN would not entrain to light ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
469
Why do high school students with later start times tend to perform better academically? * these teens have faster growth rates. * they are less sensitive to entrainment. * they are less sensitive to zeitgebers * there are shifts in circadian rhythms that occur around puberty.
there are shifts in circadian rhythms that occur around puberty ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
470
In the typical sleep pattern of healthy adults, the first REM period of the night may last a few minutes while the last REM period is likely to: * last much longer * last the same amount of time * last much less time * REM does not occur later in the night
last much longer ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
471
According to research on circadian rhythms and performance, which football team would have an advantage in a game played in Los Angeles, CA that began at 6pm local time (9 PM EST)? * a team from the east coast * any team, as long as they were playing against the Packers * neither team would have an advantage * a team from the west coast
a team from the west coast ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
472
One method to measure the activity of thousands of neurons in the brain is to conduct a(n) ________. * electroencephalogram * all answers are correct * sleep tracking device * snapshot of the brain using MRI
electroencephalogram ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
473
Tanya Tucker wakes up from a nap feeling groggy, nauseous and disoriented. What stage of sleep was she likely in just before she awoke? * stage 1 * SWS * REM * stage 2
sws ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
474
How does exposing learners to an odor during learning and sleep impact learning? * it decreased recall speed * it increased amount learned * it decreased amount learned * it increased recall speed
| GOT THIS WRONG -- IT IS NOT "IT INCREASED RECALL SPEED" ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
475
Which of the following is NOT part of SCN cell activity? * clock and cycle form a dimer * clock and cycle inhibit the activity of cry and per * the cycle repeats approximately every 24 hours * glutamate "syncs" the activity to light exposure
clock and cycle inhibit the activity of cry and per ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
476
From a neuroscientific perspective, being asleep and being in a coma are: * fundamentally the same * none of these answers is correct * both states of consciousness that evolved for the same purpose * both states the brain actively produces
none of these answers is correct ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
477
What key characteristic is shared in dreaming and LSD induced hallucinations? * saccadic eye movement * cognitive bizarreness * all of these answers are correct * activation of visual cortex
all of these answers are correct ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
478
------ has been identified as one possible underlying cause for sudden infant death syndrome (SIDS). * sleep apnea. * REM behavior disorder. * insomnia. * sleep paralysis.
Sleep apnea ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
479
If Tony Stark invented a device that could adjust his sleep-wake cycle while traveling across different time zones, which biological rhythm would he be manipulating? * Tidal rhythm * Circadian rhythm * Ultradian rhythm * Infradian rhythm
Circadian rhythm ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
480
If Wes Anderson were to make a film about a night of sleep, and each sleep cycle was a scene, how many scenes would he create for a typically developing young adult? * 8-9 scenes * 4-5 scenes * 6-7 scenes * 2-3 scenes
4-5 scenes ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
481
Grandpa Joe is too excited to go to sleep the entire week before going to visit the Wonka chocolate factory. This disruption in his sleep could contribute to which health condition often seen in the elderly? * COPD * Obesity * ADHD * Dementia
Dementia ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
482
Jocelyn has been waking up gasping for air and her partner has been complaining about her loud snoring. She brought this up with her doctor, who recommended she go to a specialist for a sleep study for a possible diagnosis of ----------. * COPD * Sleep paralysis * Sleep apnea * Insomnia
Sleep Apnea ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
483
In the world of Harry Potter, if a wizard suddenly falls asleep while casting spells, which stage of sleep do they likely enter first, unlike most muggles? * Stage 1 sleep * REM sleep * Slow-wave sleep (SWS) * Stage 2 sleep
REM (?) | GOT THIS WRONG ON QUIZ -- it is NOT SWS ## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
484
# Match the behavior to its cyclic description. human feeding behavior
## Footnote Unit 3 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
485
# Match the behavior to its cyclic description. sleep cycle in humans
circadian ## Footnote Unit 2 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
486
# Match the behavior to its cyclic description. melatonin release in humans
## Footnote Unit 2 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
487
# Match the behavior to its cyclic description. social behavior in humans
## Footnote Unit 2 Quiz Bio Rhythms and Sleep Quiz - Attempt 3
488
Which of the following is the strongest evidence AGAINST the idea that humans are responsive to pheromones? * there are no functional receptors for them in the VNO * only babies respond to pheromones * no other mammals respond to pheromones * there is no behavioral evidence for pheromone response
there are no functional receptors for them in the VNO ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
489
Humans have ------- senses. * many * eleven * five * limitless
Many | DOUBLE CHECK (got this wrong on quiz) ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
490
Golgi tendon organs are to ----- as muscle spindles are to --------. * stretch; tension * tension; stretch * paresis; proprioception * proprioception; paresis
tension; stretch ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
491
EMG studies have revealed that a voluntary movement of the arm, for example, when asked to pull a lever, is immediately preceded by * a brief cessation of breathing. * a postural response. * rapid eye movements. * recruitment of muscle fibers according to the "size principle."
a postural response ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
492
The pyramidal motor system begins in the ----- cortex, and the pathway then travels to the ------- and then the -------. * frontal; thalamus; medulla * parietal; medulla; pons * frontal; medulla; spinal cord * parietal; thalamus; medulla
frontal; medulla; spinal cord ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
493
The ----- ear contains the tiny chain of bones that facilitate sound conduction. * pinna * middle * external * inner
middle ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
494
Which statement best describes the human auditory cortex? * It is specialized to detect sounds containing many frequencies and complex patterns. * It is specialized to detect high-frequency sounds. * It is specialized to detect low-frequency sounds. * It is specialized to detect simple and pure tones.
it is specialized to detect sounds containing many frequencies and complex patterns ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
495
The tiny bones of the middle ear are collectively known as the * scala media. * stapes. * otoliths. * ossicles.
ossicles ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
496
Ion channels are pulled open and positive ions enter the cell, leading to depolarization in this type of transduction. * chemotransduction * phototransduction * somatotransduction * mechanotransduction
mechanotransduction | (in notes it is mechanoelectrical transduction) ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
497
When you look at the blue sky on clear day, your perception of the blue color is produced by * infrared rays. * gamma rays. * long-wavelength photons. * short-wavelength photons.
Answered short-wavelength photons but this is wrong -- need to figure out why ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
498
What is responsible for the lack of photoreceptors at the optic disc and consequent blind spot? * It is the location where blood vessels and ganglion cell axons leave the eye. * It is a location with a high density of pigment obscuring photoreceptor cells. * It is point of attachment for eye muscles. * It is the location where parts of the two optic nerves cross the midline.
it is the location where blood vessels and ganglion cell axons leave the eye ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
499
The bending of light rays by the optical components of the eye is called * diffraction. * refraction. * fractionation. * polarization.
refraction ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
500
------- --------- in the retina at the back of the eye cause action potentials to transmit visual information to the brain. * all of these answers are correct * horizontal cells * ganglion cells * amacrine cells
ganglion ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
501
The tastes salty and sour are elicited when taste cells ________. * are perceived only at the front of the tongue where there are taste cells * are activated by the production of saliva * are stimulated by simple ions acting on ion channels in taste cell membranes * all of these answers are correct
are stimulated by simple ions acting on ion channels in taste cell membranes | got this wrong on quiz ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
502
In nature, ________ tastes often signal the presence of toxins or poisons. * sweet * bitter * salty * spicy
bitter ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
503
Which animal would be MOST likely to consume a spicy pepper because they are not sensitive to capsaicin? * Crow * Squirrel * Cat * Dog
crow ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
504
Which of the following is correct about the cause of Benign Paroxysmal Positional Vertigo? * it is caused by alcohol consumption * it is the least common cause of vertigo * it is caused by the inappropriate movement of the otoliths into the semicircular canals * all of these answers are correct
it is caused by the inappropriate movement of the otoliths into the semicircular canals ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
505
Which structure is not part of the vestibular system? * Utricle * Saccule * Eustachian tube * Semicircular canals
Eustachian tube ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
506
Which event signals the brain that the head has moved? * The activation of efferent fibers in the semicircular canals * The opening of ion channels on stereocilia * The deflecting of the stereocilia in the ampulla * The sound latency difference between the two ears
the deflecting of the stereocilia in the ampulla ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
507
------- is the experience of nausea brought on by unnatural passive movement. * Sensorineural movement * Motion sickness * Conduction motion * Motion shadows
motion sickness ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #1
508
Damage to the ---- would most likely result in serious, extensive disruptions to a person's ability to detect sensory stimuli. * somatic nervous system * sensory nervous system * none of these answers is correct * autonomic nervous system
somatic nervous system ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
509
A motor unit is a * single motor neuron and all the muscle fibers it innervates. * single motor neuron and a single muscle fiber. * collection of neuron that travel to the same muscle group. * collection of neuron that produce the same movement.
single motor neuron and all the muscle fibers it innervates ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
510
Nervous system motor plans must balance a trade-off between * speed and accuracy. * complexity and accuracy. * complexity and force. * force and precision.
speed and accuracy ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
511
The stapes connects to the * malleus. * tympanic membrane. * oval window. * round window.
oval window ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
512
Each level of the auditory system shows ------- mapping. * tonotopic * topographic * tomographic * tonic
tonotopic ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
513
Sound latency differences between the two ears allows an animal to * dampen sounds. * amplify sounds. * determine if a sound is biologically relevant. * localize sounds.
localize sounds ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
514
Visual acuity is highest in the region of the retina called the * iris. * fovea. * lens. * optic disc.
fovea ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
515
Having a hearing deficit in one ear would likely lead to difficulty with which of the following? * locating a sound's source * detecting high amplitude sounds * describing the timbre of a sound * detecting high pitch sounds
locating a sound's source ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
516
Which property is not a dimension of color perception? * Saturation * Brightness * Complexity * Hue
Complexity ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
517
Which of the following is correct? * the part of the eye where light is refracted by the cornea is the blind spot * a portion of the retina with the most receptors is the optic disk * the part of the eye which contains rods and cones is the blind spot * the point at which ganglion cell axons leave the eye is the optic disk
the point at which ganglion cell axons leave the eye is the optic disk ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
518
In the retina, when illuminated, cone receptors that connect to an on-center bipolar cell cause ------ in the on-center bipolar cell. * no change * a depolarization * an action potential * a hyperpolarization
a depolarization | got this wrong on quiz - answered "a hyperpolarization" ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
519
The taste map ----. * all of these answers are correct * is an inaccurate representation of the human taste system * is well supported by over 100 years of scientific data * correctly shows how humans detect taste
is an inaccurate representation of the human taste system ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
520
--------- are a class of drugs that mimic --------- pain-fighting chemicals called endorphins. * endorphins; endogenous * opiates; exogenous * opiate; endogenous * endorphins; exogenous
opiate; endogenous ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
521
The -------- contains the receptor cells for the vestibular system. * pinna * organ of Corti * vestibular nuclei * ampulla
ampulla | got this wrong on quiz - answered organ of Corti ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
522
The vestibular system informs the brain about * forces that act within the body cavities. * stimulation of the autonomic nervous system. * acoustic stimuli. * the movement and position of the body.
the movement and position of the body ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #2
523
Sensory conflict theory argues that we feel badly when we receive contradictory sensory messages. Passengers on an airplane in turbulence may experience an uncomfortable conflict between ----- and --- information. * vestibular; motor * vestibular; visual * visual; motor * visual; auditory
vestibular; visual ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
524
According to lecture, which receptor results in the faster pain signal: TRPV1 or TRPM3? * TRPM3, because it works on unmyelinated axons * TRPV1, because it works on myelinated axons * TRPV1, because it works on unmyelinated axons * TRPM3, because it works on myelinated axons
TRPM3, because it works on myelinated axons ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
525
Loss of this sense has been identified as an early symptom in neurodegenerative disorders including Alzheimer's disease. * olfaction * gustation * proprioception * somatosensation
olfaction ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
526
Because of the location of rods in the retinal periphery, it is best to look ---- to see a dim stimuli, like a distant star. * behind * slightly off center * very off center * directly at
slightly off-center ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
527
Which statement about color perception is true? * The trichromatic hypothesis is supported at the level of the retina. * The opponent-process hypothesis is consistent with current research on cones. * Spectrally opponent cells are found only in the eye. * Research has largely refuted both the opponent-process and the trichromatic theories of color perception.
| GOT THIS WRONG - it's not "Research has largely refuted..." ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
528
The receptive fields of retinal ganglion cells are * columnar. * concentric. * complex. * hypercomplex.
concentric ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
529
The canals of the cochlea are filled with ----; thus, sound is carried in the form of -------. * fluid; waves * ampullae; waves * air; wind * hair cells; mechanical motion
fluid; waves (need to double-check) | GOT THIS WRONG - NOT hair cells; mechanical motion ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
530
The stereocilia of the hair cells contact the * auditory nerve fibers. * basilar membrane. * tectorial membrane. * inner hair cells.
tectorial membrane ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
531
Mirror neurons are especially interesting to researchers because * they appear to trigger specific movements. * All of the above * they might be part of a neural system for empathy. * they fire when a monkey sees another monkey (or human) performing a simple movement previously performed by the monkey itsel
All of the above ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
532
Some individuals born without a ----- still show normal motor skills. * cerebellum * hippocampus * thalamus * cingulate
cerebellum ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
533
There is strong scientific evidence for a sense of ----- in humans. * nociception * extrasensory perception * telekinesis * telpathy
nociception ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #3
534
Which of the following examples would likely lead to the release of substance P in the spinal cord? * smelling a rose * drinking alcohol * touching a hot stove * seeing a rainbow
touching a hot stove ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #4
535
Being able to tell a grape jellybean from a lime one uses requires us to detect the ------ of the candy. * smell * flavor * taste * all of these answers are correct
all of these answers are correct ## Footnote Unit 2 Quiz - Sensation and Perception - Attempt #4
536
* Because of the location of rods in the retinal periphery, it is best to look -----to see a dim stimuli, like a distant star. * directly at * slightly off center * behind * very off center
slightly off center
537
The ----- muscles are essential for accommodation. * extraocular * ciliary * orbital * lentiform
ciliary
538
Simple cortical visual cells are most likely to be activated by * bars of particular width, orientation, and location in the visual field. * movement of a bar or edge. * a boundary between two hues. * biologically relevant information.
bars of particular width, orientation, and location in the visual field | GOT THIS WRONG - it's not movement of a bar or edge
539
The blind spot in our visual field is created by -- at the -- * densely packed cones; lens * thicker photoreceptors; optic nerve * a lack of photoreceptors; optic disc * fewer rods; fovea
a lack of photoreceptors, optic disk
540
The -- funnels sound waves to the ear canal. Sound arriving at the -- causes it to vibrate, causing movement of the ---. Vibration then moves fluid in the inner ear, activating hair cells in the ---- * pinna; ossicles; tympanic membrane; cochlea * cochlea; pinna; tympanic membrane; ossicles * pinna; tympanic membrane; ossicles; cochlea * pinna; cochlea; tympanic membrane; ossicles
pinna; tympanic membrane; ossicles; cochlea
541
Inner hair cells release the neurotransmitter -- and outer hair cells release the neurotransmitter --. * ACh; GABA * glutamate; GABA * glutamate; ACh * GABA; glutamate
glutamate; ACh
542
Biceps and triceps are * reciprocals. * synergists. * muscle fibers. * antagonists.
antagonists
543
Motor neurons are referred to as the "final common pathway" because they are the * part of the dorsal motor system closest to the brainstem. * last motor neurons in a chain that actually innervates the muscle. * the only pathway by which the brain and spinal cord can control movement. * white matter of the spinal cord.
the only pathway by which the brain and spinal cord can control movement
544
Light enters the eye and causes chemical changes that lead to depolarization of ganglion cells, resulting in action potentials being sent to the brain. This is an example of ---- * sensation * reintotophic activity * perception * transduction
transduction
545
-- is a condition marked by stimuli in one modality causing the involuntary experience of a different sensation in another modality. * synesthesia * dystonia * apraxia * dysarthria
synesthesia
546
The neurotransmitter -- is produced and released by motor neurons to stimulate skeletal muscles. * serotonin * dopamine * glutamate * acetylcholine
acetylcholine
547
When athletes work out to improve their stamina, one of the goals is to enhance their * neural motor plans. * fast-twitch muscle fibers. * muscle spindles. * slow-twitch muscle fibers.
slow-twitch muscle fibers
548
Which structure is not part of the external or middle ear? * Pinna * Tympanic membrane * Organ of Corti * Stapedius muscle
Organ of Corti
549
If a person facing forward hears a sound to her left, * her left ear hears exactly twice as well as her right ear. * she must turn away from the sound to allow for spectral filtering. * she experiences no onset disparity. * her right ear will be cast in a sound shadow.
her right ear will be cast in a sound shadow
550
The brighter the light stimuli, the ------ a photoreceptor will hyperpolarize. * slower * none of these answers is correct * less * more
more
551
These two sensory systems are found in close physical proximity in the tongue. * taste; somatosensation * olfaction; somatosensation * taste; olfaction * taste; proprioception
taste; somatosensation | GOT THIS WRONG - answer is NOT taste; olfaction
552
Just prior to voluntarily moving of the arms, for example, to pull a lever, a person will adjust their --------. This is an example of ------ * legs; motor planning * torso; mirror neurons * eyes; proprioception * posture; ataxia
legs; motor planning
553
Lesions of the extrapyramidal system typically interfere with spinal reflexes by * temporarily blocking them. * causing seizure activity upstream in the cortex. * eliminating them. * exaggerating them.
exaggerating them
554
The boundaries of visual objects are enhanced through the process of * lateral inhibition. * spatial-frequency. * extrastriate perception. * visual acuity.
lateral inhibition
555
People with normal color vision have more ----- receptors than ---- receptors, and the precise proportions of these receptors ------ among individuals. * L; M; are always the same * L; M; can vary * S; M; are always the same * S; M; can vary
L; M; can vary
556
Taste is ----- represented, meaning that each side of the tongue has its own nerve supply. * unilaterally * multimodally * contralaterally * bilaterally
bilaterally
557
The only sensory system with direct connections to cognitive areas responsible for memory and emotion. * vision * nociception * olfaction * gustation
olfaction