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2S PC & TC > U8.1.2 DRUGS OF ABUSE > Flashcards

U8.1.2 DRUGS OF ABUSE Flashcards

1
Q

Hallucinogens

Substances that cause hallucinations

A

LSD, PCP, Ketamine, Scopolamine

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2
Q

Hallucinogens

  • Lysergic acid diethylamide Claviceps purpurea
  • synthetic agent related to ergot alkaloids
A

LSD

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3
Q

Hallucinogens

  • NE, dopamine, serotonin
  • 5-HT1a & 5-HT1c agonists
A

LSD

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4
Q

Hallucinogens

  • one of the most potent drugs 1ug/kg
  • absence of known fatalities
A

LSD

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5
Q

Hallucinogens

  • duration based on dose
  • waxing and waning e ffects
A

LSD

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6
Q

Hallucinogens

Symptoms :
rise in body temp, Hallucinations, uterine contractions, elevated sugar levels, Goosebumps, Euphoria, pupil dilation

A

LSD

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7
Q

Hallucinogens

  • Lophophora williamsii
  • Restricted but allowed occasionally to North
    American Indians
A

Mescaline

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8
Q

Hallucinogens

Psilocybe mushroom

A

Psilocybin

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9
Q

Hallucinogens

Symptoms :
Mydriasis, muscle relaxation, dizziness

A

Psilocybin

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10
Q

Hallucinogens

Anesthetic, “special K” “vitamin K”

A

Ketamine

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11
Q

Hallucinogens

Symptoms : dream-like states, hallucination, delirium, amnesia,
high BP, depression, fatal respiratory problems

A

Ketamine

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12
Q

Hallucinogens

  • phenylcyclohexamine derivative
  • veterinary anesthetic
A

Phencyclidine

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13
Q

Hallucinogens

angel dust, PCP

A

Phencyclidine

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14
Q

Hallucinogens

  • smoked with tobacco, snorted, Oral, IV
  • antagonize NMDA
A

Phencyclidine

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15
Q

Hallucinogens

  • long t1/2
  • users tend to be violent and suicidal
  • bad-trips
A

Phencyclidine

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16
Q

Hallucinogens

Hyoscyamus niger

A

Scopolamine

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17
Q

Hallucinogens

  • block central muscarinic receptors
  • unpleasant to users
A

Scopolamine

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18
Q

Hallucinogens

Erythroxylon coca

A

Cocaine

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19
Q

Hallucinogens

  • dopaminergic reuptake transmitter
  • inhibit reuptake of dopamine and NE
A

Cocaine

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20
Q

Hallucinogens

  • free base is absorbed as fast as IV
  • t1/2= 1hr, repeated 30min
A

Cocaine

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21
Q

Hallucinogens

Symptoms :
- feeling of bugs under skin
- paranoia and schizophrenia like state
- exhaustion by lack of sleep and food
- appetite, exhaustion, depression

A

Cocaine

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22
Q

Hallucinogens

  • increase catecholinergic neurotransmitters
  • dopamine not be metabolized thus released
A

Amphetamines

23
Q

Hallucinogens

  • treat narcolepsy and ADHD
A

Amphetamines

24
Q

Hallucinogens

paranoid psychosis, necrotizing arteritis, OD is rarely fatal

A

Amphetamines

25
Q

Hallucinogens

Symptoms:
Decreased appetite, inc. stamina, energy, sexual
drive, loss of REM sleep, tremor, restlessness, anxiety,

A

Amphetamines

26
Q

Hallucinogens

related drugs (shabu, ecstasy)

A

Amphetamines

27
Q

Hallucinogens

intimacy and empathy

28
Q

Hallucinogens

  • “raves” designer drug
  • SERT
29
Q

Substance of Abuse

reverse the effects of fatigue on both mental and physical tasks

A

Stimulants

30
Q

Substance of Abuse (Stimulants)

tobacco products

31
Q

Substance of Abuse

coffee, tea, some soft drinks, and many non-prescription medicines

32
Q

Substance of Abuse

Nicotiana tobacum

33
Q

Substance of Abuse

nicotinic cholinergic receptor agonist

34
Q

Substance of Abuse

strong psychological and physiological dependence (more addictive than heroin and cocaine)

35
Q

Substance of Abuse

  • increased dopamine
  • SIDS, carcinogenic
36
Q

Substance of Abuse

xanthine alkaloid from Coffea arabica

A

Caffeine (1,3,7-trimethylxanthine)

37
Q

Substance of Abuse

  • adenosine receptors
  • low chance of abuse and addiction
A

Caffeine (1,3,7-trimethylxanthine)

38
Q

Substance of Abuse

  • anesthetic gases
  • industrial solvents
39
Q

Substance of Abuse

  • aerosol propellants
  • organic nitrites
40
Q

Substance of Abuse

psychoactive effects

41
Q

Substance of Abuse

Symptoms :
alcohol-like intoxications, hallucinations, hypoxia, pneumonia, cardiac failure, headache, nausea, vomiting, slurred speech, loss of motor coordination, wheezing

42
Q

Substance of Abuse

difficulty in concentrating, dreaminess, euphoria, numbness, tingling

A

Anesthetics

43
Q

Substance of Abuse

  • N2O= 35% used; 100% death
  • ether & chloroform
A

Anesthetics

44
Q

Substance of Abuse

  • gasoline, toluene, benzene, trichloro-ethylene
  • euphoria, “drunk” feeling, disorientation, slow passage of time
A

Industrial solvents

45
Q

Substance of Abuse

Eg. Glue, correction fluid, gas

A

Industrial solvents

46
Q

Substance of Abuse

  • amyl nitrite, isobutyl nitrite
  • dizziness, rapid heart rate, lowered BP, “speeding,” flushing of skin
A

Organic nitrites

47
Q

Substance of Abuse

  • enhance, prolong erection
A

Organic nitrites

48
Q

Substance of Abuse

  • Liver, kidney, peripheral nerve, and brain damage
  • bone marrow suppression, pulmonary disease, death
A

Toxicities

49
Q

Substance of Abuse

bone growth, appetite, puberty, muscle growth

A

Anabolic Steroids

50
Q

Substance of Abuse

Symptoms:
change in libido, irritability, violence, mood swings, forgetfulness, confusion, fatigue, depressed mood, craving for steroids

A

Anabolic Steroids

51
Q

Substance of Abuse

hypertrophied muscles, acne, oily skin, hirsutism in females, gynecomastia in males, needle punctures

A

Anabolic Steroids

52
Q

Substance of Abuse

high LDL; low HDL

A

Anabolic Steroids

53
Q

Substance of Abuse

elevated liver function

A

Anabolic Steroids

2S PC & TC (17 decks)

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