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2S PC & TC > U8.1.2 DRUGS OF ABUSE > Flashcards

U8.1.2 DRUGS OF ABUSE Flashcards

1
Q

Hallucinogens

Substances that cause hallucinations

A

LSD, PCP, Ketamine, Scopolamine

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2
Q

Hallucinogens

  • Lysergic acid diethylamide Claviceps purpurea
  • synthetic agent related to ergot alkaloids
A

LSD

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3
Q

Hallucinogens

  • NE, dopamine, serotonin
  • 5-HT1a & 5-HT1c agonists
A

LSD

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4
Q

Hallucinogens

  • one of the most potent drugs 1ug/kg
  • absence of known fatalities
A

LSD

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5
Q

Hallucinogens

  • duration based on dose
  • waxing and waning e ffects
A

LSD

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6
Q

Hallucinogens

Symptoms :
rise in body temp, Hallucinations, uterine contractions, elevated sugar levels, Goosebumps, Euphoria, pupil dilation

A

LSD

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7
Q

Hallucinogens

  • Lophophora williamsii
  • Restricted but allowed occasionally to North
    American Indians
A

Mescaline

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8
Q

Hallucinogens

Psilocybe mushroom

A

Psilocybin

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9
Q

Hallucinogens

Symptoms :
Mydriasis, muscle relaxation, dizziness

A

Psilocybin

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10
Q

Hallucinogens

Anesthetic, “special K” “vitamin K”

A

Ketamine

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11
Q

Hallucinogens

Symptoms : dream-like states, hallucination, delirium, amnesia,
high BP, depression, fatal respiratory problems

A

Ketamine

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12
Q

Hallucinogens

  • phenylcyclohexamine derivative
  • veterinary anesthetic
A

Phencyclidine

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13
Q

Hallucinogens

angel dust, PCP

A

Phencyclidine

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14
Q

Hallucinogens

  • smoked with tobacco, snorted, Oral, IV
  • antagonize NMDA
A

Phencyclidine

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15
Q

Hallucinogens

  • long t1/2
  • users tend to be violent and suicidal
  • bad-trips
A

Phencyclidine

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16
Q

Hallucinogens

Hyoscyamus niger

A

Scopolamine

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17
Q

Hallucinogens

  • block central muscarinic receptors
  • unpleasant to users
A

Scopolamine

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18
Q

Hallucinogens

Erythroxylon coca

A

Cocaine

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19
Q

Hallucinogens

  • dopaminergic reuptake transmitter
  • inhibit reuptake of dopamine and NE
A

Cocaine

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20
Q

Hallucinogens

  • free base is absorbed as fast as IV
  • t1/2= 1hr, repeated 30min
A

Cocaine

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21
Q

Hallucinogens

Symptoms :
- feeling of bugs under skin
- paranoia and schizophrenia like state
- exhaustion by lack of sleep and food
- appetite, exhaustion, depression

A

Cocaine

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22
Q

Hallucinogens

  • increase catecholinergic neurotransmitters
  • dopamine not be metabolized thus released
A

Amphetamines

23
Q

Hallucinogens

  • treat narcolepsy and ADHD
A

Amphetamines

24
Q

Hallucinogens

paranoid psychosis, necrotizing arteritis, OD is rarely fatal

A

Amphetamines

25
Hallucinogens Symptoms: Decreased appetite, inc. stamina, energy, sexual drive, loss of REM sleep, tremor, restlessness, anxiety,
Amphetamines
26
Hallucinogens related drugs (shabu, ecstasy)
Amphetamines
27
Hallucinogens intimacy and empathy
Ecstacy
28
Hallucinogens - “raves” designer drug - SERT
Ecstacy
29
Substance of Abuse reverse the effects of fatigue on both mental and physical tasks
Stimulants
30
Substance of Abuse (Stimulants) tobacco products
Nicotine
31
Substance of Abuse coffee, tea, some soft drinks, and many non-prescription medicines
Caffeine
32
Substance of Abuse Nicotiana tobacum
Nicotine
33
Substance of Abuse nicotinic cholinergic receptor agonist
Nicotine
34
Substance of Abuse strong psychological and physiological dependence (more addictive than heroin and cocaine)
Nicotine
35
Substance of Abuse - increased dopamine - SIDS, carcinogenic
Nicotine
36
Substance of Abuse xanthine alkaloid from Coffea arabica
Caffeine (1,3,7-trimethylxanthine)
37
Substance of Abuse - adenosine receptors - low chance of abuse and addiction
Caffeine (1,3,7-trimethylxanthine)
38
Substance of Abuse - anesthetic gases - industrial solvents
Inhalants
39
Substance of Abuse - aerosol propellants - organic nitrites
Inhalants
40
Substance of Abuse psychoactive effects
Inhalants
41
Substance of Abuse Symptoms : alcohol-like intoxications, hallucinations, hypoxia, pneumonia, cardiac failure, headache, nausea, vomiting, slurred speech, loss of motor coordination, wheezing
Inhalants
42
Substance of Abuse difficulty in concentrating, dreaminess, euphoria, numbness, tingling
Anesthetics
43
Substance of Abuse - N2O= 35% used; 100% death - ether & chloroform
Anesthetics
44
Substance of Abuse - gasoline, toluene, benzene, trichloro-ethylene - euphoria, “drunk” feeling, disorientation, slow passage of time
Industrial solvents
45
Substance of Abuse Eg. Glue, correction fluid, gas
Industrial solvents
46
Substance of Abuse - amyl nitrite, isobutyl nitrite - dizziness, rapid heart rate, lowered BP, “speeding,” flushing of skin
Organic nitrites
47
Substance of Abuse - enhance, prolong erection
Organic nitrites
48
Substance of Abuse - Liver, kidney, peripheral nerve, and brain damage - bone marrow suppression, pulmonary disease, death
Toxicities
49
Substance of Abuse bone growth, appetite, puberty, muscle growth
Anabolic Steroids
50
Substance of Abuse Symptoms: change in libido, irritability, violence, mood swings, forgetfulness, confusion, fatigue, depressed mood, craving for steroids
Anabolic Steroids
51
Substance of Abuse hypertrophied muscles, acne, oily skin, hirsutism in females, gynecomastia in males, needle punctures
Anabolic Steroids
52
Substance of Abuse high LDL; low HDL
Anabolic Steroids
53
Substance of Abuse elevated liver function
Anabolic Steroids

2S PC & TC (17 decks)

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