U1 LEC: INTRODUCTION TO HISTOPATH Flashcards

1
Q

Latin, pathos means?

A

disease

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2
Q

Latin, logos means?

A

treatise

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3
Q

Latin, pathologia

A

a treatise of disease

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4
Q

Greek, pathos means?

A

suffering

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5
Q

Greek, logia means?

A

study

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6
Q

Complete greek word

A

pathologikos

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7
Q

Pathology is also called as?

A

Pathobiology

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8
Q

This is the influence of magic or supernatural.

A

Anisim

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9
Q

This is the deficiency or excess body fluids.

A

Humors

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10
Q

Father of Medicine

A

Hippocrates

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11
Q

This is the postmortems & gross pathology (300BC).

A

Morbid anatomy

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12
Q

He discovered the microscope in 17th century.

A

Anton van Leewenhoek

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13
Q

This is the study of cells

A

Cellular pathology

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14
Q

Father of Pathology

A

Rudolf Virchow

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15
Q

1632 oil painting

A

The Anatomy Lesson of Dr. Nicolaes Tulp

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16
Q

This is the study of the nature, causes, processes, development, consequences of disease and the modifications in cellular function and changes in cellular structure produced in any cell, organ, or part of the body by disease i.e. disease originates at the cellular level.

A

Pathology (Virchow)

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17
Q

This arises from alterations in molecules (genes, proteins, etc.) that influences the survival and behavior of cells.

A

Cellular disturbance

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18
Q

This is the foundation of modern pathology.

A

Understanding the cellular and molecular abnormalities that give rise to disease.

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19
Q

Pathogenesis

A

pathos (suffering) + genesis (Creation)

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20
Q

This refers to the development of disease and the chain of events leading to that disease.

A

Pathogenesis

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21
Q

This refers to the biological mechanism that leads to a diseased state.

A

Pathogenesis

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22
Q

This describes the abnormal condition.

A

Pathology

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23
Q

This explains the physiological processes because of which such condition develops and progresses.

A

Pathophysiology

24
Q

This refers to the functional changes associated resulting from disease or injury.

A

Pathophysiology

25
Q

A physician who studies all aspects of disease, on the nature, causes, and development of abnormal conditions, structural and functional changes that result from the process.

A

Pathologist

26
Q

A physician specialized in the interpretation and diagnoses of the gross, microscopic, and molecular cause by disease in the body.

A

Pathologist

27
Q

This is the laboratory specialist behind the front-line clinical team.

A

Pathologist

28
Q

This is a laboratory professional who performs diagnostic analysis on blood, urine, and body fluids.

A

Medical Technologist (MT)

29
Q

This MT is specialized in histopathologic techniques.

A

Histotechnologist

30
Q

This is the examination of cells or tissues from a living organism to diagnose disease or to confirm findings of normality.

A

Biopsy

31
Q

This is routinely biopsied to determine whether they are benign or malignant.

A

Tumor

32
Q

This is the partial removal of a small portion of tissues to sample only a representation portion of the lesion of interest.

A

Incision biopsy

33
Q

Forms of incision biopsy

A
  • wedges
  • cylindrical pieces
  • cores
  • punch
  • scrapings
34
Q

Excision biopsy is also called a?

A

Wide local incision

35
Q

This involves surgical removal of a tumor and some normal tissue around it.

A

Excision biopsy

36
Q

This refers to amount of normal tissue taken which depends on the size, histologic type, and thickness of tumor.

A

Surgical Margin

37
Q

Greek autopsia

A

to see for oneself

38
Q

Greek autos

A

oneself

39
Q

Greek opsis

A

sight, view

40
Q

Other terms for Autopsy

A
  • Post-mortem Examination
  • Obduction
  • Necropsy
  • Autopsia cadaverum
41
Q

This is a thorough examination of a corpse by dissection to determine cause, mode, and manner of death to evaluate any disease or injury.

A

Autopsy

42
Q

This is the systematic examination of a cadaver for study or for determining the cause of death.

A

Autopsy

43
Q

Autopsy uses many methodical procedures to determine what?

A
  • etiology and pathogenesis
  • epidemiology
  • establishment of genetic causes
  • family counsel
  • improvement of safety standards for the living
44
Q

Inaguration of brand new St. John Paul II building

A

July 4, 2019

45
Q

The Department of Anatomic Pathology consists of the following areas:

A
  • Gross Specimen Examination
  • Tissue and Slide Processing, Microtomy, Staining
  • Reception
  • FNAB room
  • Frozen and Cytopathology
  • Fluorescence Microscopy
  • Immunohistochemistry
  • Tissue Banking
  • Slide Archival
  • Consultant Working Areas
  • Office of Chairman and CMT
  • Morgue
46
Q

This room is used for renal and skin biopsies.

A

Fluorescence Microscopy room

47
Q

FNAB stands for?

A

Fine Needle Aspiration Biopsy

48
Q

Training Program

under Proper receiving of specimens

A
  • Identification
  • Labeling
  • Logging /Recording
  • Fixation
49
Q

Training Program

under Assisting in the gross cutting of specimens

A
  • Jots down gross description
  • Prepares corresponding number tag
50
Q

Training Program

under Assist loading of the tissue processor

A
  • Dehydration
  • Clearing
  • Paraffin infiltration
  • Embedding
51
Q

Training Program

under Microtomy

A
  • Block Orientation
  • Rough cutting, soaking, chilling
  • Ribonning
  • Floatation
  • Oven-drying
52
Q

This is used in the Rapid Frozen Section to prepare slide sections for fats, lipids, and immunofluorescence microscopy using unfixed tissues.

A

Leica CM1860 UV Freezing Microtome

53
Q

Training Program

under Staining

A
  • Haematoxylin & Eosin (H&E)
  • Papanicolau (Pap smear)
  • Special Stains
  • Immunohistochemistry
54
Q

Training Program

after Staining

A
  • Coverslipping or Slide mounting
  • Labeling
  • Reagent and Solution Preparation
  • Filing of slides and blocks
55
Q

Training Program

A
  1. Proper receiving
  2. Assist in gross cutting
  3. Assist loading
  4. Microtomy
  5. Staining
  6. Coverslipping/Slide mounting
  7. Labeling
  8. Reagent and Solution Prep
  9. Filing