Tumours

Question 1

receptors in breast cancer

Answer 1

her 2 and er

Question 2

extraaxial arachinoid cap

Answer 2

meningioma

Question 3

what does lynch syndrome predispose you to

Answer 3

colorectal ovarian and endometrial carcinoma

Question 4

lynch syndrome genetics

Answer 4

aut dom mutation in dna mismatch repair genes

Question 5

haemangioma associated with what disease

Answer 5

vhl

Question 6

describe locular breast cancer

Answer 6

atypical lobular hyperplasia <50% LCIS >50%

Question 7

what are the three main classes of ovarian tumour@?

Answer 7

epithelial germ cell stromal cell

Question 8

what are the main germ cell tumours of the ovaries?

Answer 8

dysgerminoma yolk sac choriocarcinoma teratoma embrinoma

Question 9

microsatellite instability

Answer 9

lynch syndrome

Question 10

indian file pattern seen in

Answer 10

invasive lobular carcinoma of the breast

Question 11

where does ovarian cancer met to?

Answer 11

stomach colon breast pancreas

Question 12

what are the two main tumours of the muscle of the uterus?

Answer 12

leiomyoma (benign uterine fibroid) leiomyosarcoma

Question 13

what is the main symptom of a uterine pathology ?

Answer 13

post menopausal bleeding

Question 14

treat ovarian cancer

Answer 14

paclitaxel carboplatin hrt

Question 15

describe serous uterine cancer

Answer 15

most severe early peritoneal spread associated with a tp53 mutation high grade by nature derived from serous endometrial intraepithelial carcinoma

Question 16

what is the pathway of investigations done for cervical cancer?

Answer 16

smear culposcopy actewhite punch biopsy

Question 17

what is the most common form of endometrial cancer?

Answer 17

endometrioid

Question 18

treat gbm with

Answer 18

temozolamide

Question 19

what are the tumours associated with endometriosis and lynch syndrome?

Answer 19

clear cell endometrioid

Question 20

treat cervical cancers with

Answer 20

lletz

Question 21

who grade 2

Answer 21

low grade astrocytoma – frontal and temporal lobes

Question 22

who grade 4

Answer 22

gbm – butterfly appearance older patienst

Question 23

meningioma associated with what disease

Answer 23

nf2

Question 24

phyllodes tumous

Answer 24

biphasic stromal overgrowth

Question 25

hpv types …. causes …. of the cervx

Answer 25

16 and 18 koilocytosis

Question 26

oligodendroglioma

Answer 26

toothpaste appearance frontal love

Question 27

how do you diagnose ovarian pathology?

Answer 27

ca125 cae brca 1/2 hcg afp biopsy

Question 28

what are the two main types of uterine cancer?

Answer 28

type one is endomteriod (adenocarninoma) type two is serous

Question 29

describe endomteriod cancer@?

Answer 29

most common least severe adenocarcinoma derived from atypical hyperplasia grows from unopposed oestrogen

Question 30

what is the biggest risk factor for endometrial uterine pathology?

Answer 30

obesity -- unopposed oestrogen

Question 31

what are the epithelial ovarian tumours?

Answer 31

mucinous serous clear cell brenner - transitional cell endomterila

Question 32

toothpaste ppearance

Answer 32

oligodendroglioma

Question 33

what are the two main types of cervical cancer and what type of endothelium are they derived from?

Answer 33

squamous - ectocervix adenocarcinoma - endocervix

Question 34

what is cin

Answer 34

preinvasive cervical cancer of the transformation zone

Question 35

what are the types of endometrial hyperplasia

Answer 35

simple complex atypical

Question 36

fibrocystic change

Answer 36

blue domed metaplasia

Question 37

what are the main types of ovarian cyst?

Answer 37

epithelial mesothelial follicular luteal endomtetriotic

Question 38

test for dcis

Answer 38

stereotactic vacuum assisted core biopsy

Question 39

meningioma

Answer 39

extraaxial so usually do not infiltrate the brain arachinoid cap

Question 40

who grade 1

Answer 40

pilocytic astrocytoma -- bipolar cells with long hair like projections

Question 41

what are the main stromal cell tumours of the ovaries?

Answer 41

Leydig/ Sertoli (thecal) granulosa fibroma

Question 42

what is the scoring system for ovarian pathology?

Answer 42

ca125 x menopause score x us score \>200

Question 43

haemangioblastoma

Answer 43

benign cystic highly vascular posterior fossa - cerebellar dysfuction

Question 44

who grade 3

Answer 44

anaplastic astrocytoma a

Question 45

sclerosing

Answer 45

proliferation of acini and stroma radial scar

Question 46

describe ductal breast cancer

Answer 46

atypical hyperplasia or dcis

Question 47

bipolar cells with long hair like projections

Answer 47

pilocytic astrocytoma

Question 48

fibroademoa

Answer 48

aa woman