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Year 3 Exam Cue Cards > Tumours > Flashcards

Tumours Flashcards

1
Q

receptors in breast cancer

A

her 2 and er

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2
Q

extraaxial arachinoid cap

A

meningioma

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3
Q

what does lynch syndrome predispose you to

A

colorectal ovarian and endometrial carcinoma

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4
Q

lynch syndrome genetics

A

aut dom mutation in dna mismatch repair genes

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5
Q

haemangioma associated with what disease

A

vhl

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6
Q

describe locular breast cancer

A

atypical lobular hyperplasia <50% LCIS >50%

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7
Q

what are the three main classes of ovarian tumour@?

A

epithelial germ cell stromal cell

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8
Q

what are the main germ cell tumours of the ovaries?

A

dysgerminoma yolk sac choriocarcinoma teratoma embrinoma

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9
Q

microsatellite instability

A

lynch syndrome

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10
Q

indian file pattern seen in

A

invasive lobular carcinoma of the breast

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11
Q

where does ovarian cancer met to?

A

stomach colon breast pancreas

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12
Q

what are the two main tumours of the muscle of the uterus?

A

leiomyoma (benign uterine fibroid) leiomyosarcoma

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13
Q

what is the main symptom of a uterine pathology ?

A

post menopausal bleeding

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14
Q

treat ovarian cancer

A

paclitaxel carboplatin hrt

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15
Q

describe serous uterine cancer

A

most severe early peritoneal spread associated with a tp53 mutation high grade by nature derived from serous endometrial intraepithelial carcinoma

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16
Q

what is the pathway of investigations done for cervical cancer?

A

smear culposcopy actewhite punch biopsy

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17
Q

what is the most common form of endometrial cancer?

A

endometrioid

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18
Q

treat gbm with

A

temozolamide

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19
Q

what are the tumours associated with endometriosis and lynch syndrome?

A

clear cell endometrioid

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20
Q

treat cervical cancers with

A

lletz

21
Q

who grade 2

A

low grade astrocytoma – frontal and temporal lobes

22
Q

who grade 4

A

gbm – butterfly appearance older patienst

23
Q

meningioma associated with what disease

A

nf2

24
Q

phyllodes tumous

A

biphasic stromal overgrowth

25
Q

hpv types …. causes …. of the cervx

A

16 and 18 koilocytosis

26
Q

oligodendroglioma

A

toothpaste appearance frontal love

27
Q

how do you diagnose ovarian pathology?

A

ca125 cae brca 1/2 hcg afp biopsy

28
Q

what are the two main types of uterine cancer?

A

type one is endomteriod (adenocarninoma) type two is serous

29
Q

describe endomteriod cancer@?

A

most common least severe adenocarcinoma derived from atypical hyperplasia grows from unopposed oestrogen

30
Q

what is the biggest risk factor for endometrial uterine pathology?

A

obesity – unopposed oestrogen

31
Q

what are the epithelial ovarian tumours?

A

mucinous serous clear cell brenner - transitional cell endomterila

32
Q

toothpaste ppearance

A

oligodendroglioma

33
Q

what are the two main types of cervical cancer and what type of endothelium are they derived from?

A

squamous - ectocervix adenocarcinoma - endocervix

34
Q

what is cin

A

preinvasive cervical cancer of the transformation zone

35
Q

what are the types of endometrial hyperplasia

A

simple complex atypical

36
Q

fibrocystic change

A

blue domed metaplasia

37
Q

what are the main types of ovarian cyst?

A

epithelial mesothelial follicular luteal endomtetriotic

38
Q

test for dcis

A

stereotactic vacuum assisted core biopsy

39
Q

meningioma

A

extraaxial so usually do not infiltrate the brain arachinoid cap

40
Q

who grade 1

A

pilocytic astrocytoma – bipolar cells with long hair like projections

41
Q

what are the main stromal cell tumours of the ovaries?

A

Leydig/ Sertoli (thecal) granulosa fibroma

42
Q

what is the scoring system for ovarian pathology?

A

ca125 x menopause score x us score >200

43
Q

haemangioblastoma

A

benign cystic highly vascular posterior fossa - cerebellar dysfuction

44
Q

who grade 3

A

anaplastic astrocytoma a

45
Q

sclerosing

A

proliferation of acini and stroma radial scar

46
Q

describe ductal breast cancer

A

atypical hyperplasia or dcis

47
Q

bipolar cells with long hair like projections

A

pilocytic astrocytoma

48
Q

fibroademoa

A

aa woman

Year 3 Exam Cue Cards (21 decks)

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