Endo Flashcards

1
Q

treat pcos

A

pill cyprotetorne acetate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the three types of ovulation disorders?

A

hypothalamic pituitary - pcos hypothalamic ovarian

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

increased pth decreased ca increased phosphate

A

pseudohypoparathyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

hyperthyroid oatient in 1st trimester of preg

A

propyuracil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is pseudohypoparathyroidism

A

resistance to pth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

t4

A

dit and dit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

t3/4 high tsh low

A

primary hyperthyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

autoimmune hyperthyroid

A

graves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

diagnose di

A

water deprivation test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is dka

A

insulin deficiency then an increase in counter regulatory hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

t3/4 high tsh high

A

secondary hyperthyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

treat dka

A

insulin potassium and glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

follicular cells secrete ….

A

thyroglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

autoimmune hypothyroid

A

hashimoto

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

give what drug in mody

A

sulphonylureas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is primary hyperparathyodi

A

overactive gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

t1 autoantibodies

A

anti gad and anti islet cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

zona glomerulosa

A

aldosterone (raas)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

which thyroid nodule spreads via lymphatics

A

papillary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is primary aldosteronism

A

adrenal hyperplasia and conns (tumour of xona glomerulsoa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

low t3/4 low tsh

A

secondary hypothyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

diagnose diabetes on

A

fasting glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what moves on swallowing

A

thyroglossal duct cyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are the two types of cushings

A

actg dependent - adenoma in pituitary acth independent - adrenal carcinoma/ malignancy (lung/ thymus) / exogenous steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

parafollicular cells secrete

A

calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

which thyroid nodule spreads haematogenously

A

follicular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

eg ddp4i

A

gliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

what is hhs

A

hypovolaemia glucose >30 hyperosmolar >320

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

very very low thyroid hormones

A

myxoedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

diagnose adrenocortical hypofunction

A

short synacthen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

diagnose cushings

A

low dose dexamethasone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

treat addisons crisis

A

IV hydrocortisone IV saline IV sliding scale insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

treta hypothyroid

A

levothyroxine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

diagnose primary aldosteronis

A

saline suppression test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

medulla

A

catecholamines ( sympathetic ns)

36
Q

treat siadh

A

fluid restriction and tolvaptan

37
Q

what is siadh

A

adh secreted in response to a non osmoic stimulus causing water retention

38
Q

treat adrenocortical hypofunction

A

hydrocortisone and flurocortisone

39
Q

low t3/4 high tsk

A

primary hypothyroidism

40
Q

what is pcos

A

high testosterone high lh insulin resistance

41
Q

zona reticularis

A

sex hormones (androgens)

42
Q

treat hypoparathyroid

A

ca and vit d

43
Q

what secretes the catecholamines in phaeochromocytoma

A

chromaffin cells

44
Q

in phaechromocytoma what should you screen for

A

check the thyroid in case of men 2

45
Q

t3

A

mit and dit

46
Q

biochem in addissons

A

low na low h20 high k hypotension

47
Q

acromegaly

A

gh excess in adults

48
Q

treat cushings

A

metyrapone +/- ketoconazole

49
Q

diabetes is diagnosed with a fasting glucose over

A

7

50
Q

treat hyperthyroid

A

carbimazole

51
Q

treat HHS

A

K and may need insulin

52
Q

autoantibodies in hashimoto

A

anti tpo

53
Q

what diabetic drugs can you use in pregnancy?

A

metformin and insulin

54
Q

gigantism

A

gh excess in kids

55
Q

treat a high prolactin

A

bromocriptine quinagolide cabergoline

56
Q

diabetes is diagnosed with a random glucose over

A

11.1

57
Q

what is secondary hyperparathyroid

A

physiologicalresponse to low ca

58
Q

treat psuedohypopatathryroidism

A

ca and vit d suppl

59
Q

men 2

A

medullary thyroid parathyroid phaeochromoytoma

60
Q

what is a phaeochromocytoma

A

catecholamine secreting tumour

61
Q

hba1c in diabetics

A

48>

62
Q

diagnose addisons

A

short synacthen

63
Q

transcription factor mutations in diabetec

A

diabetes at later stage in life

64
Q

eg sglt2

A

dapagliflozin

65
Q

pth high calcium high

A

primary hyperparathyroid or tertiary

66
Q

what is the biochem like in primary aldosteronism

A

high nacl high h20 hypertension and hypokalakaemia

67
Q

what is di

A

lack of adh so kidneys cant reabsorb water so na increases

68
Q

which thyroid nodule secretes melatonin

A

medullary

69
Q

treat primary alodsteronism

A

spironolactone

70
Q

men 1

A

pituitary adenoma parathyroid hyperplasia pancreatic tumours

71
Q

c peptide is absent in

A

type 1 diabetics but present in type 2

72
Q

eg sulphonylurea

A

glicazie

73
Q

what is addisons disease?

A

primary adrenal insufficiency with autoimmune destruction of the adrenal cortex

74
Q

pth high ca lo

A

secondary hyperparathyroid

75
Q

what is tertiary hyperparathyroidism

A

many years of secondary

76
Q

treat addisons

A

hydrocortisone

77
Q

zone fasciculata

A

cortisol (acth)

78
Q

where is a craniopharyngioma usually

A

rathkes pouch

79
Q

treat phaechromoxytoma

A

alpha (phenoxybenzamine) then beta (propranolol) blockade

80
Q

very very very high thyroid hormoens

A

thyrotoxicosis

81
Q

treat gh excess

A

pegvisomant (also cabergoline if secreting prolactin or octreotide)

82
Q

ovulation induction in pcos

A

clomifene citrate and metformin

83
Q

diagnose gh excess

A

oral glucose tolerance test

84
Q

treat hypocalcaemia

A

iv calcium gluconate 10ml 10% over 10mins

85
Q

what is diagnostic of dk a

A

ketones>3 glucose >11 ph <7.3

86
Q

glucokinase mutation

A

altered glut 2 - glucose higher than norma l

87
Q

treat di

A

desmopressin