tumours Flashcards

(31 cards)

1
Q

is primary or secondary brain tumours more common

A

secondary (mets)

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2
Q

symptoms of brain tumour

A

-headaches
-seizures
-N&V
-blurred vision
-weakness/paralysis
-speech problems
-mental/personality changes

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3
Q

CANCER headache

A

-worse on lying down or in morning
-associated N&V
-headache pattern in erratic
-tension like
-vomiting is prolonged and repetitive
-new motor weakness
-worsens with valsalva

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4
Q

where can the tumours come from

A

-mets
-meninges
-neuroepithelial tissue
-nerve sheath cells
-germ cells
-haemapoetic/lymphomas

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5
Q

astrocytoma WHO grading

A

I - pilocytic astrocytoma
II - low grade astrocytoma
III - anaplastic astrocytoma
IV - glioblastoma multiforme

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6
Q

pilocytic astrocytoma

A

-benign, slow growing
-most common in children
-often seen around cerebellum, brainstem

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7
Q

treatment for a pilocytic astrocytoma

A

surgical resection

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8
Q

low grade astrocytoma

A

benign
-vascular proliferation
-abnormal nucleus
-usually in temporal lobe or around central gyrus

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9
Q

treatment for a low grade astrocytoma

A

surgery +/- radiation or chemo

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10
Q

anaplastic astrocytoma

A

malignant
nucleus is rly rly weird
mitoses
can happen by itself or come from a lower grade one
survival 2 years

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11
Q

glioblastoma multiforme

A

-necrosis and neovascularisation
-BUTTERFLY appearance
-survival is less than 1 year
-rarely mets outside the brain

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12
Q

treatment

A

non-curative
-surgery
-radiotherapy
-cant drive after operation because of seizure risk

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13
Q

what type of tumour is an oligodendroglioma

A

glial tumour

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14
Q

where are oligodendrogliomas found

A

frontal lobes usually

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15
Q

features of oligodendrogliomas

A

-calcification
-cysts
-peritumoural haemorrhage
-greyish pink
-subarachnoid accumulations give TOOTHPASTE APPEARANCE

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16
Q

treatment for oligodendrogliomas

A

surgery
chemo
radiotherapy

17
Q

is a meningioma benign or malignant

18
Q

meningioma features

A

-extra-axial
-often asymptomatic
-headache, regional anatomical disturbance
-slow growing

19
Q

what is a meningioma en plaque

A

carpet/sheet like lesion infiltrating dura

20
Q

treatment for meningiomas

A

-surgery
-radiotherapy
-5 year survival 90%

21
Q

CT results for meningioma

A

-homogenous
-densely enhancing
-oedema

22
Q

MRI of a meningioma

A

-dural tail
-patent dural sinuses

23
Q

types of nerve sheath tumours

A

-shwannomas
-neurofibromas
-acoustic neuroma
-cerebellopontine angle tumour

24
Q

symptoms of nerve sheath tumours

A

-hearing loss
-tinnitus
-dysequilibrium
-can affect CN 5 and 7 (lose blink reflex)
-brainstem (hydrocephalus)

25
who gets germ cell (pineal) tumours
under 20 yrs males
26
what does a pineal tumour look like on CT
hyperdense and enhancing
27
two types of pineal tumour
germinomas and non-germinatous
28
what should be checked for any midline brain tumour in child
-AFP -beta-HCG -LDH
29
features of a hemangioblastoma
-bening -cystic -very vascular -associated VHL
30
name the low grade tumours
- Meningiomas - Acoustic neuromas - Pituiary tumours - Pineal tumours - Craniopharyngiomas - Neurofibromas
31
name the high grade tumours
- Gliomas and glioblastoma multiforme - Primary cerebral lymphomas - Medulloblastomas