neurotransmission Flashcards
overview of neurotransmission
what is found in the membranes at the end of pre-synaptic neurons
active zone where vesicles cluster
what is found in the membranes at the end of post synaptic neurones
neurotransmitter receptors
inotropic receptors
direct gating
The receptor is an integral component of the molecule that forms the channel it controls. Gating of channel is rapid
metabotropic receptors
indirect gating
Receptor and the channel it controls are distinct. Gating of channel is slower
GABA A receptor
inotropic
-Cl channel
GABA B receptor
metabotropic receptor
often potassium channel
what is a quanta
the release of neurotransmitter from a single vesicle
what is spatial summation
many inputs converge along a neurone to determine its output
what is temporal summation
a single input may modulate output by variation in action potential frequency of that input
sensory coding
sensory systems code for modality, intensity, location, and duration of external stimuli.
what is transduction
the conversion of a physical stimulus into a change in membrane potential (electrochemical signal)
what do nocioceptors respond to
painful stimuli
what is the receptive field
that region of sensory space whose stimulation results in a change in discharge (usually firing rate) of the neuron