Tumour pathology 3

Question 1

State the local effects of benign tumours.

Answer 1

Pressure and obstruction

Question 2

State the local effects of malignant tumours.

Answer 2

• Pressure
• Obstruction
• Tissue destruction (ulceration/infection)
• Bleeding (anaemia/haemorrhage)
• Pain

Question 3

List the systemic effects of malignant tumours

Answer 3

• Weight-loss cancer cachexia
• Secretion of hormones
• Paraneoplastic syndromes

Question 4

Excess ADH and ACTH hormones can lead both lead to what cancer?

Answer 4

Lung cancer

Question 5

List features of dysplasia.

Answer 5

Features include:

• Disorganisation of cells (Increased nuclear size, increased mitotic activity and abnormal mitosis)
• Non-invasive
• Can be graded (High grade, low grade)

Question 6

Detection at the pre-invasive stage of cancer is possible with the identification of

Answer 6

Dysplasia AND intraepithelial neoplasia