Drug Delivery Flashcards

1
Q

Drug delivery methods include

A
  • Transdermal (drug patches applied to the skin)
  • Injection based
  • Carrier based
  • Oral
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2
Q

State the different routes of administration via the GI tract.

A
  • Buccal (cheeks)
  • Oral
  • Rectal
  • Sublingual (under the tongue)
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3
Q

Absorption of drugs is most rapid where in the body?

A

Small intestine

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4
Q

State the route of administration via the GI tract for glyceryl trinitrate (GTN)

A

Sublingual

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5
Q

State the two advantages of using prodrugs.

A
  • Prolongation of duration of action

- Avoidance of degradation of the drug in the gut

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6
Q

Insulin, heparin and narcotic analgesics use what type of injection?

A

Subcutaneous (45 degrees)

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7
Q

What does enteric coating do to a tablet?

A

Delays disintegration of the tablet until it reaches the small intestine (protects drug from the stomach acid and vice versa)
(examples include aspirin and omeprazole)

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8
Q

State 3 sustained release tablets

A
  • Isosorbide
  • Mononitrate
  • Verapamil
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