Drug Delivery Flashcards
Drug delivery methods include
- Transdermal (drug patches applied to the skin)
- Injection based
- Carrier based
- Oral
State the different routes of administration via the GI tract.
- Buccal (cheeks)
- Oral
- Rectal
- Sublingual (under the tongue)
Absorption of drugs is most rapid where in the body?
Small intestine
State the route of administration via the GI tract for glyceryl trinitrate (GTN)
Sublingual
State the two advantages of using prodrugs.
- Prolongation of duration of action
- Avoidance of degradation of the drug in the gut
Insulin, heparin and narcotic analgesics use what type of injection?
Subcutaneous (45 degrees)
What does enteric coating do to a tablet?
Delays disintegration of the tablet until it reaches the small intestine (protects drug from the stomach acid and vice versa)
(examples include aspirin and omeprazole)
State 3 sustained release tablets
- Isosorbide
- Mononitrate
- Verapamil