Tumor Markers Flashcards
1
Q
Alkaline phosphatase
A
- Metastases to bone, liver
- Paget disease of bone
- Seminoma
2
Q
alpha-fetoprotein (AFP)
A
- Hepatocellular carcinoma
- Hepatoblastoma
- Yolk sac (endodermal sinus) tumor
- Testicular caner
- Mixed germ cell tumor (also B-hCG)
- Anencephaly
3
Q
B-hCG
A
- Hyatidiform moles
- Choriocarcinoma
- Testicular cancer
4
Q
CA-15-3/ CA-27-29
A
Breast cancer
5
Q
CA-19-9
A
Pancreatic adenocarcinoma
6
Q
CA-125
A
Ovarian cancer
7
Q
Calcitonin
A
Medullary thyroid carcinoma
8
Q
CEA
A
- Non-specific but produced by 70% of
- Colorectal and Pancreatic cancers
Also:
- Gastric carcinoma
- Breast carcinoma
- Medullary thyroid carcinoma
9
Q
PSA
A
- BPH, Prostatitis
- Prostate adenocarcinoma
10
Q
S-100
A
- Neural crest origin:
- Melanoma
- Neural crest tumor
- Schwannoma
Not neural crest:
-Langerhans cell histiocytes
11
Q
TRAP
A
Hairy cell leukemia (B-cell neoplasm)
12
Q
Bambesin
A
- Adrenal neuroblastoma
- Lung cancer
- Gastric cancer
