Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

USMLE 1 > Drug Side Effects > Flashcards

Drug Side Effects Flashcards

You may prefer our related Brainscape-certified flashcards:
USMLE® Step 1 flashcards
0
Q

Coronary vasospasm

A
  • Cocaine
  • Amphetamines
  • Methamphetamines
  • Triptans: sumatriptan
  • Ergotamines
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Anticholinergic

A
  • Atropine: prototypical anticholinergic
  • TCAs
  • H1 blockers: diphenhydramine
  • Digoxin
  • Low Potency Neuroleptics
  • Amantadine
  • Promethazine
  • dont give to PTs with potential for confusion/delirium or PTs with BPH, ileus problems or constipationo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cutaneous flushing

A
  • Vancomycin: red man syndrome
  • Niacin
  • Adenosine: potent vasodilation
  • Dihydropyridine CCBs: via smooth muscle relaxation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Dilated cardiomyopathy

A
  • Doxorubicin

- Daunorubicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Torsades de pointes

A

Drugs that prolong QT interval:

  • Class III K+ channel blockers
  • Class IA Na+ channel blockers
  • Macrolides
  • Haloperidol
  • Chloriquine
  • Protease inhibitors

*Tx: push IV magnesium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Agranulocytosis

A
  • Clozapine
  • Carbamazepine
  • Colchicine
  • PTU
  • Methimazole
  • Dapsone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Aplastic anemia

A
  • Chloramphenicol
  • Benzene
  • NSAIDs
  • PTU
  • Methimazole
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Thrombocytopenia

A
  • Heparin

- H2 blockers: -itidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Gray baby syndrome

A

Chloramphenicol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Hemolysis in G6PD patients

A
  • INH
  • Sulfonamides
  • Primaquine
  • High dose aspirin
  • Ibuprofen
  • Nitrofurantioin- UTI drug
  • Dapsone
  • Fava beans
  • Naphthalene
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Thrombosis

A

Oral Contraceptives

-Esp. If PT is a smoker >35 yrs of age

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pulmonary fibrosis

A
  • Bleomycin
  • Busulfan
  • Amiodarone: PFTs, LFTs, TFTs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Cough

A

ACE inhibitors

-d/t excess bradykinin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Focal to massive hepatic necrosis

A
  • Halothane
  • Acetaminophen
  • Valproic acid
  • Amanita phalloides (mushroom toxin)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pseudomembranous colitis

A
  • Clindamycin
  • Ampicillin
  • Any antibiotic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Adrenocortical insufficiency

A

Withdrawal of corticosteroids in a PT dependent on exogenous steroids

16
Q

Gynecomastia

A
  • Spironolactone
  • Digitalis
  • Cimetidine
  • Chronic alcohol use
  • Estrogens
  • Ketoconazole
  • Marijuana
17
Q

Hot flashes

A
  • Tamoxifen

- Clomiphene

18
Q

Hypothyroidism

A
  • Amiodarone
  • Lithium
  • Sulfonamides
19
Q

Gingival hyperplasia

A
  • Phenytoin

- Verapamil

20
Q

Gout

A
  • Furosemide
  • Thiazides
  • Niacin
  • Cyclosporine
  • Pyrazinamide
21
Q

Osteoporosis

A
  • Corticosteroids >3 mo

- Heparin

22
Q

Photosensitivity

A
  • Sulfonamides
  • Amiodarone
  • Tetracycline
23
Q

Stevens-Johnson syndrome

A
  • Seizure drugs: Ethosuximide, Carbamazepine, Lamotrigine, Phenytoin, Phenobarbital
  • Sulfa drugs
  • Penicillin
  • Allopurinol
24
Q

Drug-induced SLE

A
  • Sulfonamides
  • Hydralazine
  • INH
  • Phenytoin
  • Procainamide
25
Q

Tendon rupture/cartilage damage

A

Fluroquinolones

26
Q

Fanconi syndrome

A

Proximal tubular defect

  • Expired tetracycline
  • Heavy metal exposure

Also associated with Wilson’s disease

27
Q

Interstitial nephritis

A
  • Methicillin
  • NSAIDs
  • Furosemide
28
Q

Dizziness, nausea, headache, vision changes, tinnitus

A
  • Quinidine: Class IA anti-arrhythmic

- Quinine

29
Q

Nephrogenic diabetes insipidus

A
  • Lithium
  • Demeclocycline

*Tx: HCTZ

30
Q

Seizures

A
  • Bupropion
  • Imipenem/Cilastatin
  • INH
  • Tramadol
  • Metoclopramide
  • Alcohol withdrawal
  • Benzo withdrawal
31
Q

Tardive dyskinesia

A

High potency typical antipsychotics

32
Q

Disulfiram-like reaction

A
  • Metronidazole
  • certain Cephalosporins
  • Procarbazine
  • First generation sulfonylureas
  • Disulfiram
33
Q

Nephrotoxicity + Neurotoxicity

A
  • Aminoglycosides
  • Cisplatin
  • Polymyxins
34
Q

Nephrotoxicity + Ototoxicity

A
  • Aminoglycosides
  • Vancomycin
  • Loop diuretics
  • Cisplatin
35
Q

Hepatitis

A

INH

36
Q

Hemorrhagic cystitis

A
  • Cyclophosphamide

- Ifosfamide

37
Q

CYP450 inducers

A
  • Phenytoin
  • Rifampin
  • St. John’s wort
  • Barbiturates
  • Griseofulvin
  • Carbamazepine
38
Q

CYP450 inhibitors

A
  • Cimetidine
  • Ritonavir
  • Amiodarone
  • Ciprofloxacin
  • Ketoconazole
  • Acute alcohol use
  • Macrolides
  • INH
  • Grapefruit juice
  • Omeprazole
  • Sulfonamides

USMLE 1 (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions