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USMLE 1 > Biostatistics > Flashcards

Biostatistics Flashcards

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USMLE® Step 1 flashcards
0
Q

Effect of non-competitive antagonist on dose response curve

A

Shift curve down

-decr. Efficacy, decr, Vmax,

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1
Q

Effect of competitive antagonist on dose response curve

A

Shift curve to the right

-decr. Potency, incr. Km

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2
Q

Efficacy

A

Maximal effect a drug can produce

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3
Q

Potency

A

Amount of drug needed for a given effect

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4
Q

Therapeutic index

A

TD50/ ED50 = median toxic dose/median effective dose

-High TI= safer drug

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USMLE 1 (13 decks)

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