Tumor Marker Quiz

Question 1

Enzyme Tumors

Answer 1

PSA
THYMIDINE KINASE
ARYL SULFATASE b
Ck-BB

Question 2

Hormone

Answer 2

Calcitonin
PRL
ACTH
hCG

Question 3

Oncofetal antigen

Answer 3

AFP
CEA
Squamous cell antigen
Tennessee antige.

Question 4

Carbohydrate marker

Answer 4

CA 125
Episialin
DU-PAN-2

CA-19

Question 5

Non enzyme protein

Answer 5

C-peptide
IgG
B2-microglobulin
Preganancy specific antigen

Question 6

Multiple myeloma

Answer 6

BJP

Question 7

Hydatidiform mole

Answer 7

hCG

Question 8

Liver CA

Answer 8

AFP

Question 9

Intestinal CA

Answer 9

CEA

Question 10

Prostatic CA

Answer 10

PSA

Question 11

Aldolase, Alcohol Dehydrogenase, Hexokinase

Answer 11

Liver only

Question 12

CA-12

Answer 12

Ovarian, endometrial

Question 13

ACTH, Bombesin, Neurophysins

Answer 13

Small-cell lung cancers

Question 14

PSA, CK-BB

Answer 14

Prostate

Question 15

LDH, tdt, thymidine kinase

Answer 15

Leukemias

Question 16

CA-15-3, CA549, MCA

Answer 16

Ovarian, Breast

Question 17

Alkaline Phosphatase

Answer 17

Ovarian, Lung, Bone, Liver

Question 18

CA-19-9, CA 19-5, CA 242, CA-50

Answer 18

Pancreatic, GIT

Question 19

hCG

Answer 19

Embyonal, choriocarcinomas

Question 20

CA-27, CA-29

Answer 20

Breast only

Question 21

Aryl sulfatase B

Answer 21

Colon, Breast

Question 22

Catecholamine metabolites

Question 23

Calcitonin

Answer 23

Medullary thyroid

Question 24

Tennessee antigen

Answer 24

Colon, GIT, gall bladder

Question 25

Amylase

Answer 25

Pancrease only

Question 26

Oncogene

Answer 26

N-Ras
K-ras, bcl-2
N-myc
c-erb B-2
c-abl/bcr
c-myc

Question 27

What are the potential uses of tumor markers in the clinical setting?

Answer 27

Screening in general population
Differential diagnosis in symptomatic patients Clinical staging of cancer

Question 28

N-ras

Answer 28

AML, NEUROBLASTOMA

Question 29

VHL

Answer 29

Kidney

Question 30

K-ras, bcl-2

Answer 30

Lymphoma, leukemia

Question 31

DCC, APC

Answer 31

colorectal

Question 32

N-myc

Answer 32

Nueroendocrine

Question 33

P16 E-cadheria, BRCA2, RB1

Answer 33

Breast

Question 34

c-erb B-2

Answer 34

breast, ovarian, GIT

Question 35

P53

Answer 35

breast, liver, bladder,sarcomas

Question 36

WT 1

Answer 36

Wilms tumor

Question 37

C-myc

Answer 37

c-myc T- & B-lymphoma, lung

Question 38

cdk a2

Answer 38

bladder, melanoma, glioblastoma

Question 39

Chronic myeloid leukemia (CML)

Answer 39

c-abl/bcr

Question 40

Chronic myeloid leukemia (CML)

Answer 40

meningioma, neurofibromatosis 2

Question 41

NF2

Answer 41

meningioma, neurofibromatosis 2

Question 42

RB1

Answer 42

retinoblastoma, osteosarcoma

Question 43

p16

Answer 43

bladder, melanoma, glioblastoma