Tuberculosis Flashcards
What is the primary causative agent of tuberculosis?
Mycobacterium tuberculosis
True or False: Tuberculosis can be spread through the air.
True
Name the first-line drug commonly used to treat tuberculosis.
Isoniazid
Fill in the blank: The combination of Isoniazid and __________ is often used in tuberculosis treatment.
Rifampicin
What is the mechanism of action of Rifampicin?
Inhibition of bacterial RNA polymerase
Which drug is known to cause liver toxicity in tuberculosis treatment?
Isoniazid
What is the standard duration of treatment for drug-susceptible tuberculosis?
6 months
True or False: Ethambutol is effective against drug-resistant strains of Mycobacterium tuberculosis.
False
What is the role of Pyrazinamide in tuberculosis therapy?
To kill dormant bacteria in acidic environments
Which vitamin is often prescribed to counteract the side effects of Isoniazid?
Vitamin B6 (Pyridoxine)
Name a second-line drug used for multidrug-resistant tuberculosis.
Ciprofloxacin
What is the primary target of Isoniazid in Mycobacterium tuberculosis?
Mycolic acid synthesis
Fill in the blank: The Directly Observed Treatment, Short-course (DOTS) strategy is used to ensure __________ adherence.
treatment
What type of bacteria is Mycobacterium tuberculosis classified as?
Acid-fast bacillus
True or False: Rifampicin can interact with oral contraceptives, reducing their effectiveness.
True