Antifungals Flashcards
What is the primary purpose of antifungal drugs?
To treat fungal infections.
True or False: Antifungal drugs are effective against bacterial infections.
False
Name one common type of antifungal drug.
Azoles
Fill in the blank: The mechanism of action for polyene antifungals involves binding to __________.
ergosterol
What is the mechanism of action of azole antifungals?
Inhibition of ergosterol synthesis.
Which antifungal class does Amphotericin B belong to?
Polyene
True or False: Echinocandins are effective against Candida species.
True
What is a common side effect of Amphotericin B?
Nephrotoxicity
Which antifungal drug is often used as a first-line treatment for cryptococcal meningitis?
Fluconazole
What is the primary target of echinocandin antifungals?
Fungal cell wall synthesis.
True or False: Nystatin can be used systemically.
False
What is the main condition treated with terbinafine?
Onychomycosis (nail fungus)
Which antifungal drug class is known for causing liver toxicity?
Azoles
Fill in the blank: __________ are antifungal agents that inhibit the synthesis of β-(1,3)-D-glucan.
Echinocandins
What is the systemic antifungal drug typically used for treating invasive aspergillosis?
Voriconazole