Antilipidemic Agents Flashcards

1
Q

What are antilipidemic agents used for?

A

They are used to lower lipid levels in the blood, particularly cholesterol and triglycerides.

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2
Q

True or False: Statins are a type of antilipidemic agent.

A

True

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3
Q

Fill in the blank: The primary mechanism by which statins lower cholesterol is by inhibiting _______.

A

HMG-CoA reductase

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4
Q

Which class of antilipidemic agents is primarily used to lower triglycerides?

A

Fibrates

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5
Q

What is the primary side effect associated with statin use?

A

Muscle pain or myopathy

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6
Q

Name one example of a fibrate.

A

Fenofibrate

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7
Q

True or False: Bile acid sequestrants can help lower LDL cholesterol.

A

True

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8
Q

What is the mechanism of action of bile acid sequestrants?

A

They bind bile acids in the intestine, preventing their reabsorption and promoting cholesterol conversion to bile acids.

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9
Q

Which antilipidemic agent is known to increase HDL cholesterol levels?

A

Niacin

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10
Q

Multiple Choice: Which of the following is NOT a common antilipidemic agent? A) Atorvastatin B) Simvastatin C) Ibuprofen

A

C) Ibuprofen

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11
Q

What is the role of PCSK9 inhibitors in cholesterol management?

A

They lower LDL cholesterol by increasing the liver’s ability to remove LDL from the blood.

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12
Q

True or False: Omega-3 fatty acids are considered an antilipidemic agent.

A

True

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13
Q

Fill in the blank: Statins are most effective at lowering _______ cholesterol.

A

LDL

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14
Q

Name a potential side effect of fibrates.

A

Increased risk of gallstones

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15
Q

What is the recommended lifestyle change to complement antilipidemic therapy?

A

Adopting a heart-healthy diet and regular exercise

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16
Q

Multiple Choice: Which antilipidemic agent is primarily used for its triglyceride-lowering effects? A) Atorvastatin B) Gemfibrozil C) Ezetimibe

A

B) Gemfibrozil

17
Q

What is the primary benefit of using combination therapy in antilipidemic treatment?

A

It can provide a more comprehensive lipid profile management.

18
Q

Fill in the blank: Ezetimibe works by inhibiting the intestinal absorption of _______.

A

Cholesterol

19
Q

True or False: Regular monitoring of liver enzymes is necessary for patients on statins.

A

True

20
Q

What is a common brand name for atorvastatin?

A

Lipitor

21
Q

What class of drug is ezetimibe?

A

Cholesterol absorption inhibitor

22
Q

Multiple Choice: Which of the following is a risk factor for hyperlipidemia? A) Sedentary lifestyle B) Regular exercise C) Balanced diet

A

A) Sedentary lifestyle

23
Q

Name one contraindication for using statins.

A

Active liver disease

24
Q

What is the target LDL cholesterol level for most patients on antilipidemic therapy?

A

Below 70 mg/dL for high-risk patients

25
Q

True or False: Niacin can cause flushing as a side effect.

A

True

26
Q

Which antilipidemic agent is often used to treat familial hypercholesterolemia?

A

PCSK9 inhibitors

27
Q

Fill in the blank: The primary goal of antilipidemic therapy is to reduce the risk of _______.

A

Cardiovascular disease

28
Q

What is a key consideration when prescribing fibrates?

A

Assessing for potential drug interactions, especially with statins.

29
Q

Multiple Choice: Which of the following is a common side effect of niacin? A) Constipation B) Flushing C) Insomnia

A

B) Flushing

30
Q

What lifestyle modification can enhance the effectiveness of antilipidemic agents?

A

Weight loss

31
Q

True or False: An increasing number of patients with dyslipidemia are being treated with lifestyle changes alone.

A

True