Antilipidemic Agents Flashcards
What are antilipidemic agents used for?
They are used to lower lipid levels in the blood, particularly cholesterol and triglycerides.
True or False: Statins are a type of antilipidemic agent.
True
Fill in the blank: The primary mechanism by which statins lower cholesterol is by inhibiting _______.
HMG-CoA reductase
Which class of antilipidemic agents is primarily used to lower triglycerides?
Fibrates
What is the primary side effect associated with statin use?
Muscle pain or myopathy
Name one example of a fibrate.
Fenofibrate
True or False: Bile acid sequestrants can help lower LDL cholesterol.
True
What is the mechanism of action of bile acid sequestrants?
They bind bile acids in the intestine, preventing their reabsorption and promoting cholesterol conversion to bile acids.
Which antilipidemic agent is known to increase HDL cholesterol levels?
Niacin
Multiple Choice: Which of the following is NOT a common antilipidemic agent? A) Atorvastatin B) Simvastatin C) Ibuprofen
C) Ibuprofen
What is the role of PCSK9 inhibitors in cholesterol management?
They lower LDL cholesterol by increasing the liver’s ability to remove LDL from the blood.
True or False: Omega-3 fatty acids are considered an antilipidemic agent.
True
Fill in the blank: Statins are most effective at lowering _______ cholesterol.
LDL
Name a potential side effect of fibrates.
Increased risk of gallstones
What is the recommended lifestyle change to complement antilipidemic therapy?
Adopting a heart-healthy diet and regular exercise
Multiple Choice: Which antilipidemic agent is primarily used for its triglyceride-lowering effects? A) Atorvastatin B) Gemfibrozil C) Ezetimibe
B) Gemfibrozil
What is the primary benefit of using combination therapy in antilipidemic treatment?
It can provide a more comprehensive lipid profile management.
Fill in the blank: Ezetimibe works by inhibiting the intestinal absorption of _______.
Cholesterol
True or False: Regular monitoring of liver enzymes is necessary for patients on statins.
True
What is a common brand name for atorvastatin?
Lipitor
What class of drug is ezetimibe?
Cholesterol absorption inhibitor
Multiple Choice: Which of the following is a risk factor for hyperlipidemia? A) Sedentary lifestyle B) Regular exercise C) Balanced diet
A) Sedentary lifestyle
Name one contraindication for using statins.
Active liver disease
What is the target LDL cholesterol level for most patients on antilipidemic therapy?
Below 70 mg/dL for high-risk patients
True or False: Niacin can cause flushing as a side effect.
True
Which antilipidemic agent is often used to treat familial hypercholesterolemia?
PCSK9 inhibitors
Fill in the blank: The primary goal of antilipidemic therapy is to reduce the risk of _______.
Cardiovascular disease
What is a key consideration when prescribing fibrates?
Assessing for potential drug interactions, especially with statins.
Multiple Choice: Which of the following is a common side effect of niacin? A) Constipation B) Flushing C) Insomnia
B) Flushing
What lifestyle modification can enhance the effectiveness of antilipidemic agents?
Weight loss
True or False: An increasing number of patients with dyslipidemia are being treated with lifestyle changes alone.
True
