Trypanosoma Flashcards
Trypanosoma is divided into mainly two types:
T. Sarcoraria and T. Salivaria
Life cycle finished, transmission, location & reservoir of T.stercoraria and T.salivaria:
Chagas disease is caused by:
Trypanosoma cruzi
T. STERCORARIA
Trypanosoma cruzi is found in which geographic region
T. STERCORARIA
Latin America
T. STERCORARIA:
Species, hosts (reservoir), vector, subgenus
T. SALIVARIA:
Species, hosts (reservoir), vector, subgenus
- What is the causative agent of chronic sleeping-sickness?
- Which geographic area does the disease occur?
- Trypanosoma brucei gambiense
- West Africa
(The disease is aka “West African sleeping sickness”)
T. SALIVARIA
- What is the causative agent of acute sleeping-sickness?
- Which geographic area does the disease occur?
- Trypanosoma brucei rhodensiense
- East Africa
(the disease is aka “East African sleeping sickness”)
T. SALIVARIA
African trypanosomiasis is also known as?
Sleeping-sickness
Life cycle of Salivaria
Trypomastigotes in blood –> tsetse fly –> binary fission –> salivary gland –> Epimastigotes – binary fission –> Trypomastigotes –> inoculation to the host + binary fission in blood and CNS
Life cycle of Stercoraria
Trypomastigotes in blood –> Reduviid bugs –> Epimastigotes – binary fission 8-10 days –> Trypomastigotes – faces –> skin lesion –> Macrophages –> amastigotes –> lnn. –> blood –> Trypomastigotes –> Epimastigotes –> Trypomastigotes
- Which species of Trypanosoma does not depend on vector?
- What is the host for this parasite?
- T. equiperdum
- Eq
(transmission by interourse - veneral transmission)
What is the life cycle stages of Trypanosoma?
- amastigote
- promastigote
- epimastigote
- trypomastigote
describe amastigote
- oval
- contain nucleus + kinetoplast
- no flagellum
describe promastigote
- elongated shape
- kinetoplast in front of the nucleus
- flagellum
describe epimastigote
- elongated shape
- kinetoplast in front of the nucleus
- flagellum
- undulating membrane
describe trypomastigote
- elongated shape
- kinetoplast behind the nucleus
- flagellum
- undulating membrane
What diagnostic methods are used to diagnose trypanosoma?
- Direct microscopy
- Concentration method
- Serol. examination
- PCR
Diagnostics of Trypanosoma: which methods are used for Direct microscopy?
- direct blood smear
- thick stained blood smear
- thin stained blood smear
Diagnostics of Trypanosoma -Concentration methods:
- microhematocrit – centrifugation method
- Buffy coat method
Diagnostics of Trypanosoma - Serological examination methods:
- IFAT
- ELISA
- CFT
- NHA
Diagnostic of Trypanosoma equiperdum (Dourine)
T. SALIVARIA
- clin. symptoms
- microscopy
- serol. examination
- pat.anat. signs
Clinical symptoms of Trypanosoma equiperdum:
T. SALIVARIA
- edema
- skin lesions
- pruritus
- CNS damage symptoms
Microscopy of Trypanosoma equiperdum - what is seen?
T. SALIVARIA
- lavage of reproductive tract + puncture of skin lesion (movement)
Serological examination of Trypanosoma equiperdum:
T. SALIVARIA
- CFT
- ELISA
- IFA
Pat.anat. signs of Trypanosoma equiperdum:
T. SALIVARIA
- anemia
- cachexia
- skin lesions
- changes to the genitals
Host/reservoir of Trypanosoma brucei rhodensiense?
T. SALIVARIA
- man
- animal
Host/reservoir of Trypanosoma brucei gambiense?
T. SALIVARIA
- man
- dog
- monkey
- su
Host (reservoir) of Trypanosoma brucei brucei:
T. SALIVARIA
- eq
- su
- ru
- rodents