Triacylglycerides and Phospholipids Flashcards
Phosphatidic acid
Complex lipid
1st chain is phosphoryl group
Other two chains are carbon chains
L glycerol 3 phosphate role
Precursor to phosphatidic acid
True for both pathways
L glycerol 3 phosphate structure details
No double bond
Alcohol in middle and top
In the name
Why is phosphatidic acid important?
Precursor to glycerolipids and phospholipids
Why are glycerolipids and phospholipids important?
Membrane lipids = regulate curvature
Sphingolipids = self vs non self
Glycerolipids = major energy storage
Triacylglycerol structure reminder
Glycerol backbone
3 fatty acid chains
No phosphate group!!!
Glycerophospholipid structure
Same as phosphatidic acid but on O of PO4 group
Head group attached
What is the precursor to glycerolipids and phospholipids?
Glycerol 3 phosphate
Backbone precursor
Alcohol makes ya fat
Phosphatidic acid
Long chains precursor and phosphorous for lipid precursor
Fussy acid = bubble of fat for protection
Glyceroneogenesis
What PEPCK catalyzes in adipose tissue
Pyruvate to glycerol 3 phosphate
Adipose tissue slack glycerol kinase
Adipose tissue lacks what enzyme?
Glycerol kinase
Needs to use glyceroneogenesis
Glucocorticoids
Glue = sticking together two different effects
Limits PEPCK in adipose = more free FA
Promotes PEPCK in liver = more triglycerol production
Thiazolidinediones
Tea = healing = diabetes treatment
Activates PEPCK in adipose
=more free FA
Rosiglitazone
Sig nasty man = heart attack
3 aromatic rings
1 at end is symmetrical looks like a fat man raising hands ONO with S = NS= nasty man
Cortisol
Glucocorticoid
Cort = cort
