Tri B - Energy Metabolism Flashcards

1
Q

Describe catabolism and anabolism

A

Catabolism - Breakdown reactions releasing energy
Anabolism - Synthesis reactions consuming energy

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2
Q

Describe how energy is released from ATP

A

Energy stored in phosphate bonds
Released when bonds are broken

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3
Q

Describe the Krebs Cycle

A

Reactions occur in mitochondria
2 molecules of ATP are directly produced
Produces NADH and FADH2
- Donate to electrons to electron transport chain

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4
Q

Describe the Electron Transport Chain

A

Controlled release of energy
Carrier molecules - cytochromes
Electrons move from carrier to carrier –> from high energy to low energy

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5
Q

Name some uses of energy

A

Muscle contraction
Protein synthesis
Active transport

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6
Q

Describe energy balance

A

If intake > use, energy stored as fat
- Positive energy balance
If intake < use, fat stores mobilised
- Negative energy balance
If intake = use, energy balanced

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7
Q

What are the 4 sources of energy?

A
  1. Carbohydrate - 3.75 kcal/g
  2. Fat - 9 kcal/g
  3. Protein 4 kcal/g
  4. Alcohol - 7 kcal/g
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8
Q

Why is energy balance important

A

Obesity is a serious issue
BMI can measure
below 18.5 - underweight
Over 24.9 - overweight

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9
Q

What are some health risks of obesity?

A

Cardiovascular disease
Type 2 diabetes
Some cancer (breast, colon)
Problems with weight bearing joints
Respiratory problems

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10
Q

Name and describe some eating disorders

A

Anorexia nervosa - not eating enough
Bulimia - binging, making self sick
Binge eating disorder - losing control of eating

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11
Q

How much energy do we need?

A

25 yr female - 2080 kcal/day
25 yr male - 2600 kcal/day

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12
Q

What are the 3 components of energy expenditure?

A
  1. Basal Metabolic Rate
  2. Physical Activity
  3. Thermic Effect of Food
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13
Q

Describe how Basal Metabolic Rate uses energy

A

Minimum energy to survive
Accounts for 60-70% of total energy used

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14
Q

Describe how Physical Activity uses energy

A

Energy to move (standing, exercise)
Accounts for 15-30% of total energy used
Depends on duration and intensity

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15
Q

Describe prevalence of inactivity

A

69% of men and 59% of women meet current guidelines for physical activity (150 mins/week)
Sedentary behaviour - risk for cardiovascular disease and type 2 diabetes

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16
Q

Describe how the Thermic Effect of Food uses energy

A

Increased energy use after eating due to digestion and absorption of food
Accounts for ~10% of total energy use

17
Q

Name and describe some factors effecting BMR

A

Body weight - more weight, higher BMR
Body composition - higher fat %, lower BMR
Age - BMR highest in kids (growth)
Gender - BMR higher in males
- other factors : thyroid, genes, pregnancy

18
Q

Describe direct calorimetry

A

Heat given off is measured by temp in water
Very accurate but costly and doesn’t represent real life

19
Q

Describe indirect calorimetry

A

Based on relationship between energy production and O2 uptake
More energy required, more O2 uptake