Tri A - Muscle Flashcards
What are the 2 basic types of muscle?
Striated,
Smooth
Describe muscle structure
Filaments
–>Myofibrils
–>Striations
–>Muscle Fibres
–>Fascicles
–>Skeletal Muscle
What are thick and thin filaments composed of?
Thick –> Myosin
Thin –> Actin
Describe Filaments
Muscle Proteins
They overlap each other
Arranged in a 3 dimensional way
Describe the changes to a muscle when contracted
- Sarcomere is shortened
- Length of filaments remains the same
- Shortening has occurred as actin and myosin have slid past each other
- Actin/myosin overlap has increased
Describe the interaction between myosin and actin
- Relaxed: myosin heads seen
- Activated: myosin heads attach to actin, forming crossbridges
- Contracting: Myosin heads rotate, pulling the actin filaments
What causes rigor mortis?
No ATP is available so there is no detachment of the myosin heads
What prevents muscle contraction from happening all the time?
There are 2 regulatory proteins:
Troponin,
Tropomyosin
They regulate the sliding filament process but require Ca2+
Where are calcium ions released from?
The Sarcoplasmic Reticulum
What is a single muscle contraction known as?
A muscle twitch
What produces higher levels of muscle tension?
Increased frequency of stimulation
Describe the length-tension relationship
The length of muscle fibres is important in determining the force of contraction
Describe how length of filaments affects force of contraction
Too much overlap causes the filaments to interfere with each other
Not enough overlap means there are less crossbridges formed